Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T97637 | Target Info | |||
| Target Name | Glutathione S-transferase LANCL1 (LANCL1) | ||||
| Synonyms | p40; LanC-like protein 1; GPR69A; 40 kDa erythrocyte membrane protein | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | LANCL1 | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Glutathione | Ligand Info | |||||
| Structure Description | Crystal Structure of Human LanCL1 complexed with GSH | PDB:3E73 | ||||
| Method | X-ray diffraction | Resolution | 2.80 Å | Mutation | No | [1] |
| PDB Sequence |
SMDIEFMAQR
4 AFPNPYADYN14 KSLAEGYFDA24 AGRLTPEFSQ34 RLTNKIRELL44 QQMERGLKSA 54 DPRDGTGYTG64 WAGIAVLYLH74 LYDVFGDPAY84 LQLAHGYVKQ94 SLNCLTKRSI 104 TFLCGDAGPL114 AVAAVLYHKM124 NNEKQAEDCI134 TRLIHLNKID144 PHAPNEMLYG 154 RIGYIYALLF164 VNKNFGVEKI174 PQSHIQQICE184 TILTSGENLA194 RKRNFTAKSP 204 LMYEWYQEYY214 VGAAHGLAGI224 YYYLMQPSLQ234 VSQGKLHSLV244 KPSVDYVCQL 254 KFPSGNYPPC264 IGDNRDLLVH274 WCHGAPGVIY284 MLIQAYKVFR294 EEKYLCDAYQ 304 CADVIWQYGL314 LKKGYGLCHG324 SAGNAYAFLT334 LYNLTQDMKY344 LYRACKFAEW 354 CLEYGEHGCR364 TPDTPFSLFE374 GMAGTIYFLA384 DLLVPTKARF394 PAFEL |
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione. Genes Dev. 2009 Jun 15;23(12):1387-92. | ||||
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