Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T94594 | Target Info | |||
| Target Name | Pseudomonas Nicotinate-nucleotide adenylyltransferase (Pseudo nadD) | ||||
| Synonyms | nadD of Pseudomonas aeruginosa; Nicotinic acid mononucleotide adenylyltransferase of Pseudomonas aeruginosa; Nicotinatemononucleotide adenylyltransferase of Pseudomonas aeruginosa; Nicotinate-nucleotide adenylyltransferase of Pseudomonas aeruginosa; NaMN-Atase; NaMN adenylyltransferase of Pseudomonas aeruginosa; NaMN AT of Pseudomonas aeruginosa; Deamido-NAD(+) pyrophosphorylase of Pseudomonas aeruginosa; Deamido-NAD(+) diphosphorylase of Pseudomonas aeruginosa | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | Pseudo nadD | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Adenosine triphosphate | Ligand Info | |||||
| Structure Description | Crystal Structure of Nicotinic Acid Mononucleotide Adenylyltransferase from Pseudomonas aeruginosa | PDB:1YUN | ||||
| Method | X-ray diffraction | Resolution | 2.00 Å | Mutation | No | [1] |
| PDB Sequence |
GKRIGLFGGT
11 FDPVHIGHMR21 SAVEMAEQFA31 LDELRLLPNA41 RPPHRETPQV51 SAAQRLAMVE 61 RAVAGVERLT71 VDPRELQRDK81 PSYTIDTLES91 VRAELAADDQ101 LFMLIGWDAF 111 CGLPTWHRWE121 ALLDHCHIVV131 LQRPDADSEP141 PESLRDLLAA151 RSVADPQALK 161 GPGGQITFVW171 QTPLAVSATQ181 IRALLGAGRS191 VRFLVPDAVL201 NYIEAHHLYR 211
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| Ligand Name: Namn | Ligand Info | |||||
| Structure Description | Crystal Structure of Nicotinic Acid Mononucleotide Adenylyltransferase from Pseudomonas aeruginosa | PDB:1YUM | ||||
| Method | X-ray diffraction | Resolution | 1.70 Å | Mutation | No | [1] |
| PDB Sequence |
GKRIGLFGGT
11 FDPVHIGHMR21 SAVEMAEQFA31 LDELRLLPNA41 RPPHRETPQV51 SAAQRLAMVE 61 RAVAGVERLT71 VDPRELQRDK81 PSYTIDTLES91 VRAELAADDQ101 LFMLIGWDAF 111 CGLPTWHRWE121 ALLDHCHIVV131 LQRPDADSEP141 PESLRDLLAA151 RSVADPQALK 161 GPGGQITFVW171 QTPLAVSATQ181 IRALLGAGRS191 VRFLVPDAVL201 NYIEAHHLYR 211 AP
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal structure of nicotinic acid mononucleotide adenylyltransferase from Pseudomonas aeruginosa in its Apo and substrate-complexed forms reveals a fully open conformation. J Mol Biol. 2005 Aug 12;351(2):258-65. | ||||
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