Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T87981 | Target Info | |||
| Target Name | IL-1 receptor-associated kinase 3 (IRAK3) | ||||
| Synonyms | Interleukin-1 receptor-associated kinase 3; IRAK-M; IRAK-3; IL-1 receptor-associated kinase M | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | IRAK3 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Phosphothiophosphoric acid-adenylate ester | Ligand Info | |||||
| Structure Description | The IRAK3 Pseudokinase Domain Bound To ATPgammaS | PDB:6ZIW | ||||
| Method | X-ray diffraction | Resolution | 2.18 Å | Mutation | Yes | [1] |
| PDB Sequence |
ISFQNIIEGT
162 RNFHKDFLIG172 EGEIFEVYRV182 EIQNLTYAVK192 LFKCKKHWKR208 FLSELEVLLL 218 FHHPNILELA228 AYFTFCLIYP242 YMRNGTLFDR252 LQCVGDTAPL262 PWHIRIGILI 272 GISKAIHYLH282 NVQPCSVICG292 SISSANILLD302 DQFQPKLTDF312 AMAHFRLWYM 341 PEEYIRQGKL351 SIKTDVYSFG361 IVIMEVLTGC371 RVVLDHIQLR384 DLLRELMEKR 394 GLDSCLSFLD404 KKVPPCPRNF414 SAKLFCLAGR424 CAATRAKLRP434 SMDEVLNTLE 444 STQASLY
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | The IRAK3 Pseudokinase Domain Bound To ATPgammaS | ||||
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