Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T85188 | Target Info | |||
| Target Name | Reticulon-4 receptor (RTN4R) | ||||
| Synonyms | UNQ330/PRO526; RTN4R; Nogo-66 receptor; Nogo receptor; NgR | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | RTN4R | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: 2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose | Ligand Info | |||||
| Structure Description | Crystal structure of Nogo-66 Receptor | PDB:1P8T | ||||
| Method | X-ray diffraction | Resolution | 3.20 Å | Mutation | No | [1] |
| PDB Sequence |
CPGACVCYNE
36 PKVTTSCPQQ46 GLQAVPVGIP56 AASQRIFLHG66 NRISHVPAAS76 FRACRNLTIL 86 WLHSNVLARI96 DAAAFTGLAL106 LEQLDLSDNA116 QLRSVDPATF126 HGLGRLHTLH 136 LDRCGLQELG146 PGLFRGLAAL156 QYLYLQDNAL166 QALPDDTFRD176 LGNLTHLFLH 186 GNRISSVPER196 AFRGLHSLDR206 LLLHQNRVAH216 VHPHAFRDLG226 RLMTLYLFAN 236 NLSALPTEAL246 APLRALQYLR256 LNDNPWVCDC266 RARPLWAWLQ276 KFRGSSSEVP 286 CSLPQRLAGR296 DLKRLAANDL306 QGCAV
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J. 2003 Jul 1;22(13):3291-302. | ||||
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