Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T82773 | Target Info | |||
| Target Name | Casein kinase I gamma-2 (CSNK1G2) | ||||
| Synonyms | Casein kinase I isoform gamma-2; CKI-gamma 2; CK1G2 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | CSNK1G2 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: 3-Sulfinoalanine | Ligand Info | |||||
| Structure Description | Structure of casein kinase 1 gamma 2 | PDB:2C47 | ||||
| Method | X-ray diffraction | Resolution | 2.40 Å | Mutation | No | [1] |
| PDB Sequence |
PNFRVGKKIE
59 LRLGKNLYTN69 EYVAIKLEPI79 KSRAPQLHLE89 YRFYKQLSAT99 EGVPQVYYFG 109 PGKYNAMVLE120 LLGPSLEDLF130 DLCDRTFTLK140 TVLMIAIQLI150 TRMEYVHTKS 160 LIYRDVKPEN170 FLVGRPGTKR180 QHAIHIIDFG190 LAKEYIDPET200 KKHIPYREHK 210 SLTGTARYMS220 INTHLGKEQS230 RRDDLEALGH240 MFMYFLRGSL250 PWQGLKADTL 260 KERYQKIGDT270 KRATPIEVLC280 ENFPEEMATY290 LRYVRRLDFF300 EKPDYDYLRK 310 LFTDLFDRSG320 FVFDYEYDWA330 GKPLPTPI
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| Ligand Name: 5'-iodotubercidin | Ligand Info | |||||
| Structure Description | Structure of casein kinase 1 gamma 2 | PDB:2C47 | ||||
| Method | X-ray diffraction | Resolution | 2.40 Å | Mutation | No | [1] |
| PDB Sequence |
PNFRVGKKIE
59 LRLGKNLYTN69 EYVAIKLEPI79 KSRAPQLHLE89 YRFYKQLSAT99 EGVPQVYYFG 109 PGKYNAMVLE120 LLGPSLEDLF130 DLCDRTFTLK140 TVLMIAIQLI150 TRMEYVHTKS 160 LIYRDVKPEN170 FLVGRPGTKR180 QHAIHIIDFG190 LAKEYIDPET200 KKHIPYREHK 210 SLTGTARYMS220 INTHLGKEQS230 RRDDLEALGH240 MFMYFLRGSL250 PWQGLKADTL 260 KERYQKIGDT270 KRATPIEVLC280 ENFPEEMATY290 LRYVRRLDFF300 EKPDYDYLRK 310 LFTDLFDRSG320 FVFDYEYDWA330 GKPLPTPI
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | The Structure of Casein Kinase 1 Gamma 2 | ||||
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