Binding Site Information of Target

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Target General Information
Drug Binding Sites of Target
References
Target General Information  Top
Target ID T73908 Target Info
Target Name Wnt-7a protein (WNT7A)
Synonyms Protein Wnt-7a
Target Type Literature-reported Target
Gene Name WNT7A
UniProt ID
WNT7A_HUMAN
Drug Binding Sites of Target  Top
Ligand Name: Palmitoleic acid Ligand Info
Structure Description STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A PDB:4UZQ
Method X-ray diffraction Resolution 1.50 Å Mutation Yes [1]
PDB Sequence
S
Residue
Distance (Å)
SER206
1.344
Residue
Distance (Å)
References  Top
REF 1 Notum deacylates Wnt proteins to suppress signalling activity. Nature. 2015 Mar 12;519(7542):187-192.

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