Binding Site Information of Target
Target General Information | Top | ||||
---|---|---|---|---|---|
Target ID | T64410 | Target Info | |||
Target Name | Bacterial DD-carboxypeptidase (Bact vanYB) | ||||
Synonyms | vanYB; DD-peptidase; DD-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase-transpeptidase | ||||
Target Type | Successful Target | ||||
Gene Name | Bact vanYB | ||||
Biochemical Class | Peptidase | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
---|---|---|---|---|---|---|
Ligand Name: D-Alanine | Ligand Info | |||||
Structure Description | VanYB in complex with D-Alanine-D-Alanine | PDB:5ZHW | ||||
Method | X-ray diffraction | Resolution | 2.18 Å | Mutation | No | [1] |
PDB Sequence |
EWSLILVNRQ
97 NPIPAQYDVE107 LEQLSNGERI117 DIRISPYLQD127 LFDAARADGV137 YPIVASGYRT 147 TEKQQEIDEK158 VAEYKAKGYT168 SAQAKAEAET178 WVAVPGTSEH188 QLGLAVDINA 198 DGIHSTGNEV208 YRWLDENSYR218 FGFIRRYPPD228 KTEITGVSNE238 PWHYRYVGIE 248 AATKIYHQGL258 CLEEYLNTEK268
|
|||||
|
||||||
Click to View More Binding Site Information of This Target and Ligand Pair | ||||||
Ligand Name: Selenomethionine | Ligand Info | |||||
Structure Description | VanYB in complex with D-Alanine-D-Alanine | PDB:5ZHW | ||||
Method | X-ray diffraction | Resolution | 2.18 Å | Mutation | No | [1] |
PDB Sequence |
EWSLILVNRQ
97 NPIPAQYDVE107 LEQLSNGERI117 DIRISPYLQD127 LFDAARADGV137 YPIVASGYRT 147 TEKQQEIDEK158 VAEYKAKGYT168 SAQAKAEAET178 WVAVPGTSEH188 QLGLAVDINA 198 DGIHSTGNEV208 YRWLDENSYR218 FGFIRRYPPD228 KTEITGVSNE238 PWHYRYVGIE 248 AATKIYHQGL258 CLEEYLNTEK268
|
|||||
|
References | Top | ||||
---|---|---|---|---|---|
REF 1 | Structural basis for the substrate recognition of peptidoglycan pentapeptides by Enterococcus faecalis VanY(B). Int J Biol Macromol. 2018 Nov;119:335-344. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.