Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T60514 | Target Info | |||
| Target Name | Platelet glycoprotein VI (GP6) | ||||
| Synonyms | Glycoprotein 6; GPVI | ||||
| Target Type | Clinical trial Target | ||||
| Gene Name | GP6 | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: 2,5,8,11,14,17-Hexaoxaoctadecane | Ligand Info | |||||
| Structure Description | Crystal structure of the Glycoprotein VI loop truncation mutant PAVS-PAPYKN | PDB:5OU7 | ||||
| Method | X-ray diffraction | Resolution | 1.90 Å | Mutation | No | [1] |
| PDB Sequence |
SGPLPKPSLQ
11 ALPSSLVPLE21 KPVTLRCQGP31 PGVDLYRLEK41 LSSSRYQDQA51 VLFIPAMKRS 61 LAGRYRCSYQ71 NGSLWSLPSD81 QLELVATGVF91 AKPSLSAQPG101 SGGDVTLQCQ 111 TRYGFDQFAL121 YKEGDPERWY131 RASFPIITVT141 AAHSGTYRCY151 SFSSRDPYLW 161 SAPSDPLELV171 VTG
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structural insights into collagen-binding by platelet receptor Glycoprotein VI | ||||
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