Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T47107 | Target Info | |||
| Target Name | Protein kinase C gamma (PRKCG) | ||||
| Synonyms | PRKCG; PKCG; PKC-gamma | ||||
| Target Type | Successful Target | ||||
| Gene Name | PRKCG | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: D-serine | Ligand Info | |||||
| Structure Description | Crystal structure of the C2 domain of human protein kinase C gamma. | PDB:2UZP | ||||
| Method | X-ray diffraction | Resolution | 2.00 Å | Mutation | No | [1] |
| PDB Sequence |
MHTERRGRLQ
162 LEIRAPTADE172 IHVTVGEARN182 LIPMDPNGLS192 DPYVKLKLIP202 DPRNLTKQKT 212 RTVKATLNPV222 WNETFVFNLK232 PGDVERRLSV242 EVWDWDRTSR252 NDFMGAMSFG 262 VSELLKAPVD272 GWYKLLNQEE282 GEYYNVPVAD292 A
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| Ligand Name: Pyridoxal phosphate | Ligand Info | |||||
| Structure Description | Crystal structure of the C2 domain of human protein kinase C gamma. | PDB:2UZP | ||||
| Method | X-ray diffraction | Resolution | 2.00 Å | Mutation | No | [1] |
| PDB Sequence |
MHTERRGRLQ
162 LEIRAPTADE172 IHVTVGEARN182 LIPMDPNGLS192 DPYVKLKLIP202 DPRNLTKQKT 212 RTVKATLNPV222 WNETFVFNLK232 PGDVERRLSV242 EVWDWDRTSR252 NDFMGAMSFG 262 VSELLKAPVD272 GWYKLLNQEE282 GEYYNVPVAD292 A
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal Structure of C2 Domain of Protein Kinase C Gamma | ||||
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