Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T22945 | Target Info | |||
| Target Name | Antigen peptide transporter 1 (TAP1) | ||||
| Synonyms | Y3; Really interesting new gene 4 protein; RING4; Peptide transporter involved in antigen processing 1; Peptide transporter TAP1; Peptide transporter PSF1; Peptide supply factor 1; PSF1; PSF-1; ATP-binding cassette sub-family B member 2; ABCB2 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | TAP1 | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: adenosine diphosphate | Ligand Info | |||||
| Structure Description | Crystal Structure of the C-terminal ATPase domain of human TAP1 | PDB:1JJ7 | ||||
| Method | X-ray diffraction | Resolution | 2.40 Å | Mutation | No | [1] |
| PDB Sequence |
GLLTPLHLEG
501 LVQFQDVSFA511 YPNRPDVLVL521 QGLTFTLRPG531 EVTALVGPNG541 SGKSTVAALL 551 QNLYQPTGGQ561 LLLDGKPLPQ571 YEHRYLHRQV581 AAVGQEPQVF591 GRSLQENIAY 601 GLTQKPTMEE611 ITAAAVKSGA621 HSFISGLPQG631 YDTEVDEAGS641 QLSGGQRQAV 651 ALARALIRKP661 CVLILDDATS671 ALDANSQLQV681 EQLLYESPER691 YSRSVLLITQ 701 HLSLVEQADH711 ILFLEGGAIR721 EGGTHQQLME731 KKGCYWAMVQ741 A |
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. EMBO J. 2001 Sep 3;20(17):4964-72. | ||||
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