Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T17291 | Target Info | |||
| Target Name | Ammonium transporter Rh type C (RHCG) | ||||
| Synonyms | Tumor-related protein DRC2; Rhesus blood group family type C glycoprotein; Rh type C glycoprotein; Rh glycoprotein kidney; Rh family type C glycoprotein; RHGK; PDRC2; CDRC2; C15orf6 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | RHCG | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: B-Octylglucoside | Ligand Info | |||||
| Structure Description | Crystal Structure of the Human Rhesus Glycoprotein RhCG | PDB:3HD6 | ||||
| Method | X-ray diffraction | Resolution | 2.10 Å | Mutation | No | [1] |
| PDB Sequence |
SAWNTNLRWR
10 LPLTCLLLQV20 IMVILFGVFV30 RYDFENEFYY58 RYPSFQDVHV68 MVFVGFGFLM 78 TFLQRYGFSA88 VGFNFLLAAF98 GIQWALLMQG108 WFHFLQDRYI118 VVGVENLINA 128 DFCVASVCVA138 FGAVLGKVSP148 IQLLIMTFFQ158 VTLFAVNEFI168 LLNLLKVKDA 178 GGSMTIHTFG188 AYFGLTVTRI198 LYRRNLEQSK208 ERQNSVYQSD218 LFAMIGTLFL 228 WMYWPSFNSA238 ISYHGDSQHR248 AAINTYCSLA258 ACVLTSVAIS268 SALHKKGKLD 278 MVHIQNATLA288 GGVAVGTAAE298 MMLMPYGALI308 IGFVCGIIST318 LGFVYLTPFL 328 ESRLHIQDTC338 GINNLHGIPG348 IIGGIVGAVT358 AASDWTARTQ390 GKFQIYGLLV 400 TLAMALMGGI410 IVGLILRLPF420 WGQPSDENCF430 EDAVYWEMPE440 GNS |
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Function of human Rh based on structure of RhCG at 2.1 A. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9638-43. | ||||
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