Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T10844 | Target Info | |||
| Target Name | Immunoglobulin gamma Fc receptor I (FCGR1) | ||||
| Synonyms | IgG Fc receptor I; FcRI; Fc-gamma RI; FCGR1A; CD64 antigen; CD64 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | FCGR1A | ||||
| Biochemical Class | Immunoglobulin | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: 3,6,9,12,15,18-Hexaoxaicosane-1,20-diol | Ligand Info | |||||
| Structure Description | Crystal structure of Fc RI and its implication to high affinity immunoglobulin G binding | PDB:3RJD | ||||
| Method | X-ray diffraction | Resolution | 2.65 Å | Mutation | No | [1] |
| PDB Sequence |
KAVITLQPPW
30 VSVFQEETVT40 LHCEVLHLPG50 SSSTQWFLNG60 TATQTSTPSY70 RITSASVNDS 80 GEYRCQRGLS90 GRSDPIQLEI100 HRGWLLLQVS110 SRVFTEGEPL120 ALRCHAWKDK 130 LVYNVLYYRN140 GKAFKFFHWN150 SNLTILKTNI160 SHNGTYHCSG170 MGKHRYTSAG 180 ISVTVKELFP190 APVLNASVTS200 PLLEGNLVTL210 SCETKLLLQL225 YFSFYMGSKT 235 LRGRNTSSEY245 QILTARREDS255 GLYWCEAATE265 DGNVLKRSPE275 LELQVLG |
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal structure of FcGamma receptor I and its implication in high affinity Gamma-immunoglobulin binding. J Biol Chem. 2011 Nov 25;286(47):40608-13. | ||||
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