Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T08198 | Target Info | |||
| Target Name | Oxidative stress responsive 1 (OXSR1) | ||||
| Synonyms | Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein; KIAA1101 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | OXSR1 | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: AMP-PNP | Ligand Info | |||||
| Structure Description | Structure of the OSR1 kinase, a hypertension drug target | PDB:2VWI | ||||
| Method | X-ray diffraction | Resolution | 2.15 Å | Mutation | No | [1] |
| PDB Sequence |
NRDDYELQEV
22 IGTAVVQAAY35 CEKVAIKRIN49 AMSQCHHPNI75 VSYYTSFVVK85 DELWLVMKLL 95 SGGSVLDIIK105 HIVAKGEHKS115 GVLDESTIAT125 ILREVLEGLE135 YLHKNGQIHR 145 DVKAGNILLG155 EDGSVQIADF165 GVSAFLAGTP190 CWMAPEVMEQ200 VRGYDFKADI 210 WSFGITAIEL220 ATGAAPYHKY230 PPMKVLMLTL240 QNDPPSLETE255 MLKKYGKSFR 265 KMISLCLQKD275 PEKRPTAAEL285 LRHKFFQ
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| Click to View More Binding Site Information of This Target and Ligand Pair | ||||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure of the OSR1 kinase, a hypertension drug target. Proteins. 2008 Dec;73(4):1082-7. | ||||
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