Binding Site Information of Target

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Target General Information
Drug Binding Sites of Target
References
Target General Information  Top
Target ID T03644 Target Info
Target Name Synuclein alpha (SNCA)
Synonyms PARK1; Non-A4 component of amyloid precursor; Non-A beta component of AD amyloid; NACP; Alpha-synuclein
Target Type Clinical trial Target
Gene Name SNCA
Biochemical Class Synuclein
UniProt ID
SYUA_HUMAN
Drug Binding Sites of Target  Top
Ligand Name: Coenzyme A Ligand Info
Structure Description Cryo-EM structure of human NatB in complex with CoA-Alpha-Synuclein PDB:7STX
Method Electron microscopy Resolution 3.14 Å Mutation No [1]
PDB Sequence
MDVFM
Residue
Distance (Å)
MET1
2.683
Residue
Distance (Å)
References  Top
REF 1 Cryo-EM structure of human NatB in complex with CoA-Alpha-Synuclein

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