Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T99160 | Target Info | |||
| Target Name | MAP kinase signal-integrating kinase 2 (MKNK2) | ||||
| Synonyms |
Mnk2; MAPK signal-integrating kinase 2
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| Target Type | Clinical trial Target | ||||
| Gene Name | MKNK2 | ||||
| Biochemical Class | Protein kinase superfamily. CAMK Ser/Thr protein kinase family | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Melk-TI
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355059; MELK-T1; GTPL9366; BCP26188; BDBM50043341; compound 7 [PMID: 25589925]; JNJ47117096; JNJ-47117096
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| Activity |
IC50 = 760000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase. ACS Med Chem Lett. 2014 May 23;6(1):25-30. | ||||
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