Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T98642 | Target Info | |||
| Target Name | PDZ binding kinase (PBK) | ||||
| Synonyms |
TOPK; T-LAK cell-originated protein kinase; Spermatogenesis-related protein kinase; SPK protein; PDZ-binding kinase; Nori-3; MAPKK-like protein kinase; Lymphokine-activated killer T-cell-originated protein kinase; Cancer/testis antigen 84; CT84
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| Target Type | Literature-reported Target | ||||
| Gene Name | PBK | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
[1-(2-Thiophen-2-yl-1H-imidazo[4,5-b]pyridin-7-yl)piperidin-3-yl]methanamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3718855; SCHEMBL12963871
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| Activity |
IC50 = 77000 nM
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[1] | |||
| Compound Name |
N-(3-Aminophenyl)-2-thiophen-2-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL8221652; CHEMBL3718405
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| Activity |
IC50 = 96000 nM
|
[1] | |||
| Compound Name |
(S)-Tert-Butyl 3-(2-(5-bromothiophen-2-yl)-7-hydroxy-1H-benzo[d]imidazole-4-carboxamido)piperidine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2333779; CHEMBL3718349
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| Activity |
IC50 = 100000 nM
|
[2] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | WO patent application no. 2011002772A1, IMIDAZOPYRIDINE DERIVATIVES AND PBK INHIBITORS CONTAINING THE SAME | ||||
| REF 2 | US patent application no. 20110263566A1, 7-Hydroxy-benzoimidazole-4-yl-methanone Derivatives and PBK Inhibitors Containing the Same | ||||
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