Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T97174 | Target Info | |||
| Target Name | Mannose-6-phosphate receptor (M6PR) | ||||
| Synonyms |
MPRD; MPR46; MPR 46; Cation-dependent mannose-6-phosphate receptor; CDMan-6-P receptor; CD-MPR; CD Man-6-P receptor; 46kDa mannose 6-phosphate receptor; 46 kDa mannose 6-phosphate receptor
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| Target Type | Successful Target | ||||
| Gene Name | M6PR | ||||
| Biochemical Class | Mannose 6-phosphate receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Sodium;(E)-2-[(2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]ethenesulfonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL470778
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| Activity |
IC50 = 71000 nM
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[1] | |||
| Compound Name |
Sodium;2-[(2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]ethanesulfonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL469556
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| Activity |
IC50 = 150000 nM
|
[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Mannose 6-sulfonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL510805; SCHEMBL1119021; BDBM50293266
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| Activity |
IC50 = 230000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6240-3. | ||||
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