Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T91390 | Target Info | |||
| Target Name | Staphylococcus Dehydrosqualene desaturase (Stap-coc crtN) | ||||
| Synonyms |
Dehydrosqualene desaturase; 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)
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| Target Type | Literature-reported Target | ||||
| Gene Name | Stap-coc crtN | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(E)-N-Methyl-N-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-ylmethyl)but-2-en-1-amine;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827033; BDBM50188058
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN). J Med Chem. 2016 May 26;59(10):4831-48. | ||||
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