Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T90751 | Target Info | |||
| Target Name | N-acetylglucosaminyltransferase I (NAGAT1) | ||||
| Synonyms |
N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; MGAT; GlcNAc-T I; GNT-I; GLCT1; GGNT1; Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
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| Target Type | Patented-recorded Target | ||||
| Gene Name | MGAT1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
[(3R)-1-[2-[(1S)-1-(4-Chloropyrazol-1-yl)ethyl]-1H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl]-pyrrolidin-1-ylmethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3893203; SCHEMBL15322898; BDBM215629; US9296745, 196-A; US9296745, 196-B
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Chembl4280459
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Investigative | Compound Info | ||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile. Medchemcomm. 2016 Nov 22;8(4):771-779. | ||||
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