Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T89772 | Target Info | |||
| Target Name | Vesicular acetylcholine transporter (SLC18A3) | ||||
| Synonyms |
VAChT; Solute carrier family 18 member 3
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| Target Type | Discontinued Target | ||||
| Gene Name | SLC18A3 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-(2-Hydroxycyclohexyl)-9-methoxy-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL20571; BDBM50018093
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
4-Phenylpiperidine
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Investigative | Compound Info | ||
| Synonyms |
4-Phenyl-piperidine; 4-Phenyl piperidine; Piperidine, 4-phenyl-; MFCD00006002; 4-(phenyl)piperidine; UNII-8V8IM567WT; CHEMBL20969; 8V8IM567WT; 4-Phenylpiperidine 97%; 4-Phenylpiperidine, 98%; 4-phenypiperdine; 4-phenyl piperidin; EINECS 212-243-1; NSC 89743; (4-phenyl)piperidine; PubChem8009; 4-Phenylpiperidine, 97%; SCHEMBL4574; KSC490S6L; AMPD00098; CTK3J0965; UTBULQCHEUWJNV-UHFFFAOYSA-; DTXSID40227890; ALBB-005772; CS-D0605; NSC89743; STR04023; ZINC1575604; ANW-36973; BBL011820; BDBM50007408; NSC-89743; SBB014484; STK500866; 4-phenyl-1,2,3,5-tetrahydropyridine; AKOS000208931; AB00564; ACN-048438; AM85909; LF-0512; MCULE-6590774354; AC-23131; AK-44099; BR-44099; SC-06733; SY005151; AB0007441; DB-031653; ST4026652; A9776; BB 0237057; FT-0619411; P1555; B-1340; 771P993; Q-102142; Q4637198
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| Activity |
IC50 = 90000 nM
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[1] | |||
| Compound Name |
4a,9-Dihydroxy-3-(2-hydroxycyclohexyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282727; BDBM50018118
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis, in vitro acetylcholine-storage-blocking activities, and biological properties of derivatives and analogues of trans-2-(4-phenylpiperidino)cyclohexanol (vesamicol). J Med Chem. 1989 Jun;32(6):1217-30. | ||||
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