Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T79747 | Target Info | |||
| Target Name | Protein-serine O-palmitoleoyltransferase porcupine (PORCN) | ||||
| Synonyms |
Protein-cysteine N-palmitoyltransferase porcupine; Protein MG61; PORCN
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| Target Type | Clinical trial Target | ||||
| Gene Name | PORCN | ||||
| Biochemical Class | Acyltransferase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-(4-Biphenylyl)-2-(4-(1H-pyrazole-5-yl)phenoxy)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091543; SCHEMBL16198016; BDBM50233643
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
N-(4-Phenylphenyl)-2-(4-pyrrol-1-ylphenoxy)acetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091274; SCHEMBL16197962; BDBM50233638; N-(4-Biphenylyl)-2-(4-(1H-pyrrole-1-yl)phenoxy)acetamide
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery and Optimization of a Porcupine Inhibitor. J Med Chem. 2015 Aug 13;58(15):5889-99. | ||||
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