Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T78710 | Target Info | |||
| Target Name | Inward rectifier potassium channel Kir1.1 (KCNJ1) | ||||
| Synonyms |
ROMK1; Potassium channel, inwardly rectifying subfamily J member 1; Inward rectifier K(+) channel Kir1.1; ATP-sensitive inward rectifier potassium channel 1
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| Target Type | Patented-recorded Target | ||||
| Gene Name | KCNJ1 | ||||
| Biochemical Class | Inward rectifier potassium channel | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
5-[2-[4-[2-[3-Ethyl-4-(tetrazol-1-yl)phenyl]acetyl]piperazin-1-yl]ethyl]-3H-2-benzofuran-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2441413; BDBM50442623
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| Activity |
IC50 = 100000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5829-32. | ||||
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