Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T73476 | Target Info | |||
| Target Name | Antithrombin-III (ATIII) | ||||
| Synonyms |
SERPINC1; ATIII; AT3
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|
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| Target Type | Successful Target | ||||
| Gene Name | SERPINC1 | ||||
| Biochemical Class | Serpin protein | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 15 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethylbenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL611972; SCHEMBL13286823; BDBM50310306
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N-Cyclohexyl-N-(3,4-dihydroxyphenylsulfonyl)-3,4-dihydroxybenzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL601265; SCHEMBL13286829; BDBM50310311
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N-(3,4-Dihydroxyphenylsulfonyl)-N-hexyl-3,4-dihydroxybenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL596879; SCHEMBL2789250; BDBM50310309; N-(3,4-dihydroxyphenyl)sulfonyl-N-hexyl-3,4-dihydroxybenzenesulfonamide
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N,N''-Bis(3,4-dihydroxybenzenesulfonyl)piperazine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL597509; SCHEMBL13286817; BDBM50310312
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethyl-3,4-dimethoxybenzenesulfonamide)
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL599342; SCHEMBL4177072; BDBM50310299; N-[2-[(3,4-dimethoxyphenyl)sulfonyl-ethylamino]ethyl]-N-ethyl-3,4-dimethoxybenzenesulfonamide
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethyl-2,5-dihydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596860; SCHEMBL13286968; BDBM50310313
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|
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethyl-4-hydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596859; SCHEMBL13286927; BDBM50310305
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N-Benzyl-N-(3,4-dihydroxyphenylsulfonyl)-3,4-dihydroxybenzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596880; SCHEMBL13286828; BDBM50310310
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|
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| Activity |
IC50 > 300000 nM
|
[1] | |||
| Compound Name |
N-(3,4-Dihydroxyphenylsulfonyl)-3,4-dihydroxy-N-propylbenzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597478; SCHEMBL13286916; BDBM50310308
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|
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| Activity |
IC50 > 1000000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethyl-3,4-dihydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL599742; SCHEMBL13286815; BDBM50310301
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|
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| Activity |
IC50 > 1000000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethyl-3-hydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597510; SCHEMBL13286885; BDBM50310304
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|
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| Activity |
IC50 > 1000000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(N-ethyl-3,5-difluoro-4-hydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596861; SCHEMBL13286822; BDBM50310307
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|
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| Activity |
IC50 > 3000000 nM
|
[1] | |||
| Compound Name |
N,N''-(Butane-1,4-diyl)bis(3,4-dihydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL611992; SCHEMBL13287068; BDBM50310302
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|
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| Activity |
IC50 > 3000000 nM
|
[1] | |||
| Compound Name |
N,N''-(Ethane-1,2-diyl)bis(3,4-dihydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL606451; SCHEMBL13286760; BDBM50310300
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|
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| Activity |
IC50 > 3000000 nM
|
[1] | |||
| Compound Name |
N,N''-(Hexane-1,6-diyl)bis(3,4-dihydroxybenzenesulfonamide)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL599769; SCHEMBL13286937; BDBM50310303
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|
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| Activity |
IC50 > 3000000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Novel bis-arylsulfonamides and aryl sulfonimides as inactivators of plasminogen activator inhibitor-1 (PAI-1). Bioorg Med Chem Lett. 2010 Feb 1;20(3):966-70. | ||||
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