Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T71398 | Target Info | |||
| Target Name | Guanylate cyclase (GC) | ||||
| Synonyms |
Guanylyl Cyclase
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|
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| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| Biochemical Class | Phosphorus-oxygen lyase | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 6 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
1-[[(2S,4R)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL552550; SCHEMBL408339
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
1-[[2-(2-(4-Chlorophenyl)ethyl)-1,3-dithiolan-2-yl]methyl]imidazole hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL537200; 2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dithiolane hydrochloride; SCHEMBL410505
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
1-[[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL535614; SCHEMBL411620
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
1-[[(2R,4S)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL535613; SCHEMBL408546
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
1-[[2-(2-(4-Chlorophenyl)ethyl)-1,3-dioxolan-2-yl]methyl]imidazole hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL541899; SCHEMBL410852
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|
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| Activity |
IC50 > 1000000 nM
|
[1] | |||
| Compound Name |
1-[[(2R,4R)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL536056; SCHEMBL410679
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| Activity |
IC50 > 1000000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors. J Med Chem. 2006 Jul 13;49(14):4437-41. | ||||
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