Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T66040 | Target Info | |||
| Target Name | Bacterial Penicillin binding protein 2 (Bact mrdA) | ||||
| Synonyms |
PBP-2
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| Target Type | Successful Target | ||||
| Gene Name | Bact mrdA | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Sodium;(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(Z)-2-(1,3-thiazol-5-yl)ethenyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL332565
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| Activity |
IC50 = 143000 nM
|
[1] | |||
| Compound Name |
Sodium;(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(Z)-2-pyridin-2-ylethenyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL121924
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| Activity |
IC50 = 145000 nM
|
[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[(E)-3-pyridin-1-ium-1-ylprop-1-enyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;trifluoromethanesulfonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL123481
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| Activity |
IC50 = 297000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases. J Med Chem. 1996 Sep 13;39(19):3712-22. | ||||
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