Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T60077 | Target Info | |||
| Target Name | Retinoic acid receptor RXR-beta (RXRB) | ||||
| Synonyms |
Retinoid X receptor beta; Nuclear receptor subfamily 2 group B member 2; NR2B2
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| Target Type | Successful Target | ||||
| Gene Name | RXRB | ||||
| Biochemical Class | Nuclear hormone receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-[(Z)-N-Ethoxy-C-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)carbonimidoyl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2110180; BDBM50408855
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| Activity |
EC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-[(Z)-N-[(2-Methylpropan-2-yl)oxy]-C-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)carbonimidoyl]benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2110182; BDBM50408856
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| Activity |
EC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-[[(E)-Tert-Butoxyimino]-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-methyl]-benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL162827; BDBM50074298
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| Activity |
EC50 ~ 100000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells. J Med Chem. 1999 Feb 25;42(4):742-50. | ||||
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