Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59686 | Target Info | |||
| Target Name | Methyl cpg binding protein 2 (MECP2) | ||||
| Synonyms |
MethylCpGbinding protein 2; Methyl-CpG-binding protein 2; MeCp2 protein; MeCp2; MeCp-2 protein
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| Target Type | Clinical trial Target | ||||
| Gene Name | MECP2 | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 6 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-(4-Ethoxyphenyl)-4-pyridin-2-yl-1,3-thiazol-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CBMicro_027146; Oprea1_346974; CHEMBL3687969; SCHEMBL13390220; ZINC88233; CCG-2831; AKOS000565393; MCULE-7098152254; BIM-0027141.P001; EU-0076446; SR-01000477171; SR-01000477171-1
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| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
US9034574, Xviii
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3687964; SCHEMBL13390316; BDBM158509; BIM-0026554.P001
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| Activity |
IC50 > 200000 nM
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[1] | |||
| Compound Name |
5-(2-Methoxyphenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
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Investigative | Compound Info | ||
| Synonyms |
CBMicro_028107; ACMC-209ied; CHEMBL3687967; SCHEMBL13390295; SCHEMBL17071967; CTK4H3978; DTXSID30401086; ZINC4568533; ANW-28115; MFCD01152910; AKOS003816594; BIM-0028066.P001; V5423
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| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
3-Phenyl-1-(phenylthioxomethyl)-5-(trifluoromethyl)-2-pyrazolin-5-ol
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Investigative | Compound Info | ||
| Synonyms |
CBMicro_027560; CHEMBL3687965; SCHEMBL13390504; BDBM158510; AKOS024364267; US9034574, XX; MCULE-3288464196; BIM-0027821.P001; ST50996331; AG-205/33644043; 1-benzothioyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol
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| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
9-Methyl-2-(4-nitrophenyl)-9H-imidazo[1,2-a]benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CBMicro_027629; Oprea1_220837; Oprea1_252991; CHEMBL3687962; SCHEMBL13390176; SCHEMBL13408418; US9034574, Add; BDBM158507; ZINC275080; US9034574, III; 8-Methyl-2-(4-nitro-phenyl)-8H-1,3a,8-triaza-cyclopenta[a]indene; NSC751859; STK035593; AKOS000560201; MCULE-5548198789; NSC-751859; BIM-0027736.P001; EU-0038888; SR-01000439552; SR-01000439552-1; 9-Methyl-2-(4-nitrophenyl)-9H-benzo[d]imidazo[1,2-a]imidazole
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| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol
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Investigative | Compound Info | ||
| Synonyms |
KCC 07; KCC-07; 3-{[4-(pyridin-2-yl)-1,3-thiazol-2-yl]amino}phenol; CBMicro_027305; Oprea1_718651; CHEMBL3687961; SCHEMBL13390238; ZINC88152; BDBM158506; NSC752630; AKOS000563408; US9034574, II; MCULE-7998134036; NSC-752630; NS-04313; BIM-0027370.P001; HY-131031; CS-0120742; ST50028583; SR-01000477166; SR-01000477166-1; 3-[(4-(2-pyridyl)-1,3-thiazol-2-yl)amino]phenol; 3-{[4-(2-pyridinyl)-1,3-thiazol-2-yl]amino}phenol
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| Activity |
IC50 > 200000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | US patent application no. 9034574B2, Agents for reversing epigenetic silencing of genes | ||||
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