Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59550 | Target Info | |||
| Target Name | CI Man-6-P receptor (IGF2R) | ||||
| Synonyms |
MPRI; MPR 300; M6PR; M6P/IGF2R; M6P/IGF2 receptor; Insulinlike growth factor II receptor; Insulinlike growth factor 2 receptor; Insulin-like growth factor II receptor; Insulin-like growth factor 2 receptor; IGFII receptor; IGF-II receptor; Cationindependent mannose6phosphate receptor; Cation-independent mannose-6-phosphate receptor; CIMPR; CI-MPR; CD222; 300 kDa mannose 6phosphate receptor; 300 kDa mannose 6-phosphate receptor
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| Target Type | Clinical trial Target | ||||
| Gene Name | IGF2R | ||||
| Biochemical Class | Mannose 6-phosphate receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(Z)-3-(4-Hydroxyphenyl)-2-pyridin-2-ylprop-2-enenitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL43689; ZINC4347852; BDBM50409195; AKOS001301581; AB00757746-01
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| Activity |
IC50 = 77100 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structural studies on bioactive compounds. 32. Oxidation of tyrphostin protein tyrosine kinase inhibitors with hypervalent iodine reagents. J Med Chem. 2000 Apr 20;43(8):1550-62. | ||||
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