Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T56272 | Target Info | |||
| Target Name | G protein coupled receptor 81 (HCAR1) | ||||
| Synonyms |
Hydroxycarboxylic acid receptor 1; HCAR1; Gprotein coupled receptor 81; Gprotein coupled receptor 104
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| Target Type | Literature-reported Target | ||||
| Gene Name | HCAR1 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-Bromo-5-hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
Benzoic acid, 3-bromo-5-hydroxy-; 3-bromo-5-hydroxy benzoic acid; CHEMBL2146909; 3-BROMO-5-HYDROXYBENZOICACID; Benzoic acid,3-bromo-5-hydroxy-; ACMC-209ckn; SCHEMBL200289; 3-bromo-5-hydroxy-benzoic acid; 5-hydroxy-3-bromo-benzoic acid; CTK4C2222; DTXSID10577677; KS-000017MM; ANW-20565; BBL103606; BDBM50391815; MFCD06797980; STL557416; ZINC12956775; 3-Bromo-5-hydroxybenzoic acid, 97%; 5-BROMO-3-HYDROXYBENZOIC ACID; AKOS015834264; AB29744; AS06301; CM10203; CS-W014828; AK-59149; AS-19422; SC-53216; AB0033968; B4740; X8047; B-3141; J-007395
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| Activity |
EC50 = 129000 nM
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[1] | |||
| Compound Name |
3-Hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
M-HYDROXYBENZOIC ACID; m-Salicylic acid; 3-Carboxyphenol; Benzoic acid, 3-hydroxy-; m-Hba; Benzoic acid, m-hydroxy-; meta-Hydroxybenzoic acid; Acido m-idrossibenzoico; 3-Hydroxy benzoic acid; Kyselina 3-hydroxybenzoova; 3-hydroxy-benzoic acid; UNII-2ZFW40OJ7U; MFCD00002506; NSC 55746; 2ZFW40OJ7U; CHEMBL65369; m-hydroxybenzoate; 3-Hydroxybenzoic acid, 99%; Acido m-idrossibenzoico [Italian]; Kyselina 3-hydroxybenzoova [Czech]; EINECS 202-726-5; BRN 0508160; m-salicylate; AI3-03110; 3-hydroxy benzoate; meta-hydroxybenzoate; meta-salicylic acid; Benzoic acid, 3-hydroxy-, ion(1-); 3-hydroxybenzoic-acid; metahydroxybenzoic acid; PubChem9161; 3-Hydroxybenzoate, II; Enamine_005356; DSSTox_CID_1610; bmse000324; DSSTox_RID_76235; DSSTox_GSID_21610; SCHEMBL40078; KSC349K8N; DTXSID6021610; HMS1409D10; ZINC388754; ACMC-209795; KS-000000YX; NSC55746; Tox21_200527; ANW-13671; BBL011983; BDBM50336491; KM3494; NSC-55746; s6367; SBB058844; STL163473; AKOS000118958; CS-W004049; HY-W004049; MCULE-3607182166; PS-5406; NCGC00248676-01; NCGC00258081-01; AK-50288; SC-07532; 3-Hydroxybenzoic acid, analytical standard; AB0007855; DB-028515; FT-0600874; ST51038596; 3-Hydroxybenzoic acid, ReagentPlus(R), 99%; C00587; AE-562/40227537; Q2823216; W-100054; 3-Hydroxybenzoic acid, Vetec(TM) reagent grade, 98%; F9995-1635; UNII-I3P9R8317T component IJFXRHURBJZNAO-UHFFFAOYSA-N; 713EC407-4844-477D-8207-DBD66E398D2C
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| Activity |
EC50 = 184000 nM
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[1] | |||
| Non Binders of This Target (in total, 11 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
5-Hydroxynicotinic acid
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Investigative | Compound Info | ||
| Synonyms |
5-hydroxypyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-hydroxy-; 5-Hydroxy-nicotinic acid; 5-Hydroxy-3-pyridinecarboxylic acid; 5-hydroxy nicotinic acid; MFCD00129117; CHEMBL2146902; 5-hydroxynicotinicacid; BRN 0115847; NICOTINIC ACID, 5-HYDROXY-; PubChem2415; ACMC-209gz9; Oprea1_058796; Oprea1_193943; 5-22-05-00113 (Beilstein Handbook Reference); KSC202E8T; SCHEMBL186161; 5-Hydroxynicotinic acid, 97%; CTK1A2289; 5-hydroxypyridinium-3-carboxylate; DTXSID50182143; 5-hydroxypyridine-3-carboxylicacid; HMS1671H22; ZINC332673; ACT02416; BCP27371; EBD49093; KS-000006OW; 3-Hydroxypyridine-5-carboxylic acid; ANW-26275; BBL010930; BDBM50391823; NSC606891; RW1130; SBB010273; STK531022; STK801985; 3-pyridinecarboxylic acid, 5-hydroxy; AKOS000272822; AKOS005463460; AC-2839; ACN-049106; CS-W009148; LS20727; MCULE-4896018532; NSC-606891; PB33816; PS-5446; NCGC00342404-01; AK-25698; BP-21442; BR-25698; SC-03080; SY003082; 3-HYDROXY-5-PYRIDINECARBOXYLIC ACID; AB0006010; DB-009085; 3-PYRIDINECARBOXYLIC ACID,5-HYDROXY-; AM20051033; FT-0602367; FT-0621168; ST50258394; 3-Pyridinecarboxylic acid, 5-hydroxy- (9CI); EN300-73559; C-5668; AB01334129-02; 828H713; AE-848/00984004; J-400705; Q27455772; Z57124104
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3-Hydroxy-5-(trifluoromethyl)benzoic Acid
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Investigative | Compound Info | ||
| Synonyms |
3-Hydroxy-5-trifluoromethylbenzoic acid; CHEMBL2146907; Benzoic acid, 3-hydroxy-5-(trifluoromethyl)-; MFCD07368783; 3-Hydroxy-5-trifluoromethyl-benzoic acid; 3-hydroxy-5-trifluoromethylbenzoicacid; ACMC-1CPRZ; KSC496I2D; SCHEMBL477824; CTK3J6421; KS-00000NMX; DTXSID00382459; ACT00885; ANW-72881; BBL101599; BDBM50391821; CL8089; SBB093590; STL555395; ZINC15442784; AKOS005259697; AB32076; AM84002; CM12815; CS-W015347; FS-2057; 5-hydroxy-3-trifluoromethyl-benzoic acid; AC-26052; AK-34710; BR-34710; SC-52492; 5-hydroxy-3-(trifluoromethyl)benzoic acid; AB0024236; A5872; FT-0651162; W5461; S-5405; 328H698; Z1741967079
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3-Hydroxyphenylboronic acid
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Investigative | Compound Info | ||
| Synonyms |
(3-hydroxyphenyl)boronic Acid; 3-Hydroxybenzeneboronic acid; MFCD01074603; 3-Hydroxyphenylboronicacid; M-HYDROXYPHENYLBORONIC ACID; Boronic acid, (3-hydroxyphenyl)-; CHEMBL2146990; 3-Hydroxyphenylboronic acid, 97%; PubChem1728; 3-BORONOPHENOL; ACMC-209qip; 3-hydroxyphenyboronic acid; SCHEMBL8884; 3-hydroxy phenylboronic acid; 3-hydroxy-phenylboronic acid; 3-hydroxyphenyl boronic acid; 3-hydroxyphenyl-boronic acid; 3-hydroxy benzeneboronic acid; 3-hydroxylphenyl boronic acid; KSC447S9P; 3-hydroxy phenyl boronic acid; (3-hydroxyphenyl) boronic acid; (3-hydroxyphenyl)-boronic acid; (3-hydroxy-phenyl)-boronic acid; CTK3E7997; WFWQWTPAPNEOFE-UHFFFAOYSA-; DTXSID90370249; M-HYDROXYBENZENEBORONIC ACID; ACN-S003923; ACT02211; BCP03518; Boronicacid, B-(3-hydroxyphenyl)-; KS-000000KW; ANW-38639; BBL100525; BDBM50391826; SBB052523; STL554319; AKOS004116323; HEX-2-ENEDIOICACIDDIMETHYLESTER; ZINC169743259; AB08061; AS-2488; CS-W002734; LS10839; QC-1420; VB10320; 3-Hydroxyphenylboronic acid, >=95.0%; NCGC00249443-01; AC-24801; AK-44803; BP-20369; BR-44803; SC-07076; SY003747; AB0010406; DB-031699; (3-(Boc-aminomethyl)-3-hydroxyoxetan-3-ol; AM20050286; FT-0615831; B-5047; 199H186; Q-102215
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3-Hydroxy-5-methoxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2146904; Benzoic acid, 3-hydroxy-5-methoxy-; SCHEMBL618373; CTK0A0561; DTXSID30428677; 3-hydroxy-5-methoxy-benzoic acid; ZINC5046498; BDBM50391818; MFCD06655980; AKOS000277131; AB25434; AK134172; AS-50131; DA-08627; SC-71286; FT-0721622
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
5-Hydroxy-3-phenylbenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
5-Hydroxy-[1,1'-biphenyl]-3-carboxylic acid; CHEMBL2146906; ACMC-209ih9; 3-hydroxy-5-phenylbenzoic acid; SCHEMBL18706550; CTK4H4648; DTXSID50688498; 4430AB; ANW-28219; BDBM50391816; MFCD18086680; ZINC65349369; AKOS015856249; 5-Hydroxy-1,1'-biphenyl-3-carboxylic acid; 5-Hydroxy[1,1'-biphenyl]-3-carboxylic acid; A-3342
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3-t-Butyl-5-hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
3-TERT-BUTYL-5-HYDROXYBENZOIC ACID; CHEMBL2146485; 3-(tert-Butyl)-5-hydroxybenzoic acid; Benzoic acid,3-(1,1-dimethylethyl)-5-hydroxy-; 3-T-BUTYL-5-HYDROXYBENZOICACID; SCHEMBL1188570; CTK4J1756; DTXSID20618227; BDBM50391817; ZINC14986119; AKOS006326249; MB07578; W-2747; Benzoic acid, 3-(1,1-dimethylethyl)-5-hydroxy-
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
5-(2H-Tetrazol-5-yl)benzene-1,3-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2146993; BDBM50391829
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3-Cyano-5-hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
Benzoic acid, 3-cyano-5-hydroxy-; CHEMBL2146908; SCHEMBL2562951; 2257AJ; BDBM50391820; ZINC95558795; AB71614; AS06302; CM10204; MCULE-2254411035; NE40937; DA-23707; FT-0708661; Z1815157430
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
5-Hydroxy-1-oxidopyridin-1-ium-3-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2146903; BDBM50391824
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3,5-Dihydroxyphenylphosphonic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2146991; SCHEMBL6395721; BDBM50391827; (3,5-dihydroxyphenyl)phosphonic acid
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Compound Name |
3,5-Dihydroxyphenyl(Methyl)Phosphinic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2146992; SCHEMBL20518823; BDBM50391828; (3,5-dihydroxyphenyl)-methylphosphinic acid
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| Activity |
EC50 > 1000000 nM
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[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects. ACS Med Chem Lett. 2012 Jun 11;3(8):637-9. | ||||
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