Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T54229 | Target Info | |||
| Target Name | Angiogenin (ANG) | ||||
| Synonyms |
Ribonuclease 5; RNase 5; RNASE5
Click to Show/Hide
|
||||
| Target Type | Literature-reported Target | ||||
| Gene Name | ANG | ||||
| Biochemical Class | Endoribonucleases | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 2 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate]
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL401150; U-PI-A-PI; BDBM50402338; DB03186; Q27464584; 3'-O-[(3'-O-Phosphono-5'-adenylyl)oxyphosphonyl]-2'-deoxy-5'-uridylic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 360000 nM
|
[1] | |||
| Compound Name |
[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL455775; BDBM50292713; 5''-phospho-2''-deoxyuridine 3-pyrophosphate (P''->5'') adenosine 3''-phosphate
Click to Show/Hide
|
||||
| Activity |
Ki = 360000 nM
|
[2] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg Med Chem. 2012 Dec 15;20(24):7184-93. | ||||
| REF 2 | Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J Med Chem. 2009 Feb 26;52(4):932-42. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.