Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T50914 | Target Info | |||
| Target Name | Protein phosphatase 1D (PPM1D) | ||||
| Synonyms |
p53-induced protein phosphatase 1; WIP1; Protein phosphatase magnesium-dependent 1 delta; Protein phosphatase 2C isoform delta; PP2C-delta
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| Target Type | Literature-reported Target | ||||
| Gene Name | PPM1D | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
6-[2-(4-Fluoro-2-methylphenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3314467; SCHEMBL17004758; BDBM50046575
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3469-74. | ||||
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