Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T47101 | Target Info | |||
| Target Name | Fibroblast growth factor receptor 1 (FGFR1) | ||||
| Synonyms |
c-fgr; bFGF-R-1; bFGF-R; N-sam; HBGFR; Fms-like tyrosine kinase 2; FLT2; FLT-2; FLG; FGFR-1; FGFBR; CEK; CD331 antigen; CD331; Basic fibroblast growth factor receptor 1; BFGFR
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| Target Type | Successful Target | ||||
| Gene Name | FGFR1 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 157 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
1-Phenyl-1H-benzoimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenyl-1H-benzoimidazole; 2622-60-8; 1-phenyl-1H-benzo[d]imidazole; 1-phenylbenzimidazole; 1-Phenyl-1H-benzimidazole; 97542-80-8; 1H-Benzimidazole,1-phenyl-; BAS 00350928; 1H-Benzimidazole, 1-phenyl-; XNCMQRWVMWLODV-UHFFFAOYSA-N; 1-PHENYL-1H-1,3-BENZODIAZOLE; AK123264; AC1LCTXI; PubChem19972; 1-Phenyl benzoimidazole; 1-Phenylbenzimidazole 3; phenyl-1H- Benzimidazole; 1-phenyl-1,3-benzodiazole; MLS000765952; SCHEMBL157265; 1-Phenyl-1H-benzimidazole #; CHEMBL310080; BDBM3794; CTK4F7433; DTXSID10345732; 1-Phenylbenzimidazole deriv.
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
4-Benzoimidazol-1-yl-phenylamine
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Investigative | Compound Info | ||
| Synonyms |
4-(1H-benzimidazol-1-yl)aniline; 52708-36-8; 4-(1H-Benzo[d]imidazol-1-yl)aniline; 4-(1H-1,3-benzodiazol-1-yl)aniline; 4-benzimidazolylphenylamine; AC1NS4KU; 4-(benzimidazol-1-yl)aniline; AC1Q51W1; SCHEMBL1208951; BDBM3829; CHEMBL346870; CTK1H4832; DTXSID80416160; 1-Phenylbenzimidazole deriv. 46; MolPort-000-892-003; ZINC2538824; 7454AB; STK122023; 1-(4-Aminophenyl)-1H-benzimidazole; SBB022485; AKOS000200797; MCULE-3811873515; AJ-38769; DA-18573; Benzenamine, 4-(1H-benzimidazol-1-yl)-; KB-237102; ST45055167; FT-0748937; EN300-14992
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL327300; Ki-6783; 6,7-Dimethoxy-4-(3,4-dimethoxyphenoxy)quinoline; SCHEMBL925876; 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline; ZQSHUGGLESWJFP-UHFFFAOYSA-N
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
3-Substituted indolin-2-one 11c
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Investigative | Compound Info | ||
| Synonyms |
SU5402 analog 11c; BDBM4889; CHEMBL146697; SCHEMBL4407240; 3-[4-Methyl-5-(2-oxo-5-sulfamoyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic Acid
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| Activity |
IC50 ~ 50000 nM
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[4] | |||
| Compound Name |
3-(Benzimidazol-1-yl)phenol
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 27; BDBM3810; CHEMBL348706; SCHEMBL7993245; AKOS013758843; 3-(1H-1,3-benzodiazol-1-yl)phenol
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| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
Pyrido[2,3-d]pyrimidin-7(8H)-one deriv. 6d
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Investigative | Compound Info | ||
| Synonyms |
BDBM4202; CHEMBL107177; 6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]amino}-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(1-methylpiperidin-4-yl)oxyquinazolin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
Anilinoquinazoline deriv. 32; 4-Anilinoquinazoline 14; CHEMBL26050; BDBM4649; SCHEMBL1467367; 4-(4-chloro-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yloxy)quinazoline; 4-(4chloro-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yloxy)quinazoline; 7-(1-Methyl-4-piperidinyloxy)-6-methoxy-4-(2-fluoro-4-chloroanilino)quinazoline
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| Activity |
IC50 = 50000 nM
|
[6] | |||
| Compound Name |
3-Phenylbenzimidazol-5-ol
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 77; BDBM3860; CHEMBL153106; 1-phenyl-6-hydroxybenzimidazole; SCHEMBL12730486; 1-phenyl-1H-1,3-benzodiazol-6-ol; DS-021982
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(1H-Benzimidazol-1-yl)benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
SBB025753; Benzonitrile, 2-(1H-benzimidazol-1-yl)-; 2-benzimidazolylbenzenecarbonitrile; 1-Phenylbenzimidazole deriv. 23; 2-(benzimidazol-1-yl)benzonitrile; SCHEMBL840022; BDBM3806; CHEMBL359358; CTK0J3827; DTXSID30416155; MFCD09834175; STK352681; ZINC12397829; 1-(2-Cyanophenyl)-1H-benzoimidazole; AKOS000261998; MCULE-7319441304; 2-(1H-benzo[d]imidazol-1-yl)benzonitrile; 2-(1H-1,3-benzodiazol-1-yl)benzonitrile; ST45134698
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Butoxy-1-phenylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 10; CHEMBL80510; BDBM3921; SCHEMBL7993339; 5-Butoxy-1-phenyl-1H-benzimidazole; 5-butoxy-1-phenyl-1H-1,3-benzodiazole; 5-butoxy-1-phenylbenzimidazole hydrochloride
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
p38 MAP Kinase Inhibitor IX
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL259922; Kinome_3519; SCHEMBL16576573; CTK8G2239; BDBM50376226; 4-methyl-N-(1,2-oxazol-3-yl)-3-[(1-phenylpyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
1-Phenyl-1H-benzimidazole-5-thiol
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Investigative | Compound Info | ||
| Synonyms |
1-phenyl-1h-benzo[d]imidazole-5-thiol; 1-phenylbenzimidazole-5-thiol; 5-Substituted 1-Phenylbenzimidazole 23; BDBM3934; CHEMBL419653; SCHEMBL7975709; DTXSID80416165; ZINC13798298; 1-phenyl-1H-1,3-benzodiazole-5-thiol; 5-Mercapto-1-phenylbenzimidazole Hydrochloride
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-(2-Nitrophenyl)benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_111368; MLS000711112; BDBM3802; CHEMBL355950; SCHEMBL6298248; 1-Phenylbenzimidazole deriv. 19; HMS2647A22; ZINC297682; 1-(2-Nitrophenyl)-1H-benzimidazole; AKOS000665590; MCULE-6394078115; 1-(2-nitrophenyl)-1H-1,3-benzodiazole; SMR000280879; SR-01000312641; SR-01000312641-1
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzotriazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenyl-1H-benzo[d][1,2,3]triazole; 1H-Benzotriazole, 1-phenyl-; 1-Phenyl-1,2,3-benzotriazole; 1-Phenyl-1H-1,2,3-benzotriazole; 1-Phenyl-1H-benzotriazole; 1 -Phenylbenzotriazole; MLS000701318; SCHEMBL165333; BDBM3793; CHEMBL153275; 1-Phenylbenzimidazole deriv. 10; DTXSID20236940; HMS2232C05; HMS3373L11; ZINC5948185; MFCD01924397; AKOS005144667; 1-Phenyl-1H-1,2,3-benzotriazole #; DS-9238; KS-00000S76; NCGC00247176-01; AK149942; SMR000526286; AF-628/30886025; Z2186883242
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-Phenylbenzimidazole-4-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 88; SCHEMBL696547; BDBM3871; CHEMBL347553; phenyl-1H-benzo[d]imidazole-7-carboxylic acid; 1-phenyl-1H-1,3-benzodiazole-7-carboxylic acid
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Benzyl-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-benzylbenzimidazole; 1-Benzylbenzoimidazole; 1-Benzyl-1H-benzoimidazole; 1-(phenylmethyl)benzimidazole; 1H-Benzimidazole, 1-(phenylmethyl)-; benzylbenzimidazole; F0852-0025; 1-(Benzyl)benzimidazole; N-Benzyl-1H-benzimidazole; MLS000526503; 1-Benzyl-1H-benzimidazole #; SCHEMBL230002; 1-benzyl-1H-benzo[d]imidazole; BDBM3787; CHEMBL347547; IFLab1_003893; 1-Phenylbenzimidazole deriv. 4; (Phenylmethyl)-1H-benzimidazole; 1-benzyl-1H-1,3-benzodiazole; 1-benzyl-1H-1,3-benzimidazole; CTK1D0377; DTXSID60340297; HMS1423A21; HMS2493C03; N-(phenylmethyl)-1H-benzimidazole; ZINC167633; CCG-17389; SBB094065; STK804589; AKOS000283139; MCULE-5796565689; (S)-2-Benzyl-2-N-Bocamino-ethylthiol; AS-10099; SMR000116977; ST50056383; AE-907/30533008; SR-01000446470; SR-01000446470-1; Q27188896; (S)-tert-butyl 1-mercapto-3-phenylpropan-2-ylcarbamate
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-(1H-Benzo[d]imidazol-1-yl)aniline
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Investigative | Compound Info | ||
| Synonyms |
3-(benzimidazol-1-yl)aniline; 1-Phenylbenzimidazole deriv. 33; BDBM3816; CHEMBL155505; SCHEMBL2306019; 1-(3-Aminophenyl)benzimidazole; DTXSID10416158; 1175AB; ZINC13782567; AKOS015924851; 3-(1H-1,3-benzodiazol-1-yl)aniline; S-1324
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 31
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Investigative | Compound Info | ||
| Synonyms |
BDBM3814; CHEMBL358881; SCHEMBL22583692; 3-(1H-1,3-benzodiazol-1-yl)benzamide
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
1-(4-Methoxyphenyl)-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-(4-Methoxyphenyl)-1H-benzoimidazole; 1-(4-methoxyphenyl)benzimidazole; 1-(4-methoxyphenyl)-1h-benzo[d]imidazole; SMR000140586; Cambridge id 5657731; MLS000533148; BDBM3822; CHEMBL153101; SCHEMBL10695254; CTK4F7434; 1-Phenylbenzimidazole deriv. 39; DTXSID90353512; HMS2500E13; ZINC184073; AKOS004113064; 1H-Benzimidazole,1-(4-methoxyphenyl)-; 1-(4-Methoxy-phenyl)-1H-benzoimidazole; SC-63506; 1-(4-methoxyphenyl)-1H-1,3-benzodiazole; AB00092084-01; SR-01000216114; SR-01000216114-1
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
1-(4-Chlorophenyl)benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 41; BDBM3824; CHEMBL153624; 1-(4-Chlorophenyl)-1H-benzimidazole; 1-(4-chlorophenyl)-1H-1,3-benzodiazole
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
2-Phenylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
2-phenyl-1H-benzo[d]imidazole; 2-Phenyl-1H-benzimidazole; Phenizidole; Phenzidole; Phenzidol; Gainex; 2-Phenylbenzimdazole; 1H-Benzimidazole, 2-phenyl-; 2-Phenyl-1H-benzoimidazole; BENZIMIDAZOLE, 2-PHENYL-; UNII-CB9ZJ140SB; MFCD00005592; NSC 251956; CB9ZJ140SB; 2-phenyl-1H-1,3-benzodiazole; EINECS 211-939-2; BRN 0007087; phenylbenzimidazole; phenyl benzimidazole; PubChem7617; 2-phenyl benzimidazole; 2-phenyl-benzimidazole; ACMC-209ojn; 1H-Benzimidazole, phenyl-; DSSTox_CID_31033; DSSTox_GSID_52460; 2-Phenylbenzimidazole, 97%; 5-23-08-00437 (Beilstein Handbook Reference); cid_12855; KSC490O7P; MLS000701325; BIDD:GT0186; SCHEMBL105095; 1-Phenylbenzimidazole Analog 6; BDBM3789; CHEMBL153535; ZINC1932; DTXSID5052460; 2-phenyl-1H-1,3-benzimidazole; CTK3J0777; KS-00000DDD; HMS1728H19; HMS2235H23; HMS3372F02; ALBB-033235; BCP27606; Tox21_303711; ANW-36081; BBL000186; g 570; NSC251956; SBB046161; STK227880; AKOS000275572; AC-7237; CS-W010651; LS40925; MCULE-1408232727; NSC-251956; NCGC00247174-01; NCGC00357026-01; AK-50903; AS-11952; SC-06481; SMR000526282; ST097862; SY005301; BB 0241957; FT-0613322; P1105; Z-3918; AB00876270-08; 716P790; AF-407/01228019; Q-101090; BRD-K90551865-001-05-1; Q27275387; Z50129842; F0853-0315
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
6-(2,3,5,6-Tetramethylphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine
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Investigative | Compound Info | ||
| Synonyms |
6-arylpyrido[2,3-d]pyrimidine deriv. 22; BDBM3440; CHEMBL293592; SCHEMBL8129482; ZINC13862909; 6-(2,3,5,6-Tetramethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
1-[4-(1H-Benzimidazol-1-yl)phenyl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
1-[4-(benzimidazol-1-yl)phenyl]ethanone; 1-[4-(1h-benzo[d]imidazol-1-yl)phenyl]ethanone; 1-(4-(1H-Benzo[d]imidazol-1-yl)phenyl)ethanone; 1-[4-(1H-1,3-benzodiazol-1-yl)phenyl]ethan-1-one; 1-Phenylbenzimidazole deriv. 47; BDBM3830; CHEMBL153682; SCHEMBL7383547; DTXSID60407016; 4'-(1-benzimidazolyl)acetophenone; ZINC3888764; MFCD06655584; AKOS000221176; 1-(4-Acetylphenyl)-1H-benzoimidazole; CCG-291674; MCULE-4405843397; DA-31130; FT-0734342; V4716; EN300-12952; K-6712; 1-[4-(1H-Benzimidazol-1-yl)phenyl]ethan-1-one; SR-01000067600; SR-01000067600-1; Z85939917
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
Ethyl 2-(benzimidazol-1-yl)benzoate
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 17; BDBM3800; CHEMBL436465; ethyl 2-(1H-1,3-benzodiazol-1-yl)benzoate
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
1-(2-Pyridinyl)-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-pyridin-2-ylbenzimidazole; 1H-Benzimidazole, 1-(2-pyridinyl)-; 1-(pyridine-2-yl)-1H-benzo[d]imidazole; SMR000477872; N-pyridylbenzimidazole; 2-pyridinylbenzoimidazole; 2-pyridyl-1H-benzimidazole; MLS000701324; MLS001180942; BDBM3807; CHEMBL155161; SCHEMBL1346814; CTK0J3867; 1-Phenylbenzimidazole deriv. 24; DTXSID70357371; HMS2842D19; ZINC387472; 1-(2-Pyridyl)-1H-benzoimidazole; MCULE-5586216155; 1-(pyridin-2-yl)-1H-1,3-benzodiazole; 1-(Pyridin-2-yl)-1H-benzo[d]imidazole; AQ-776/42801717
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
1-Phenylbenzimidazole-5-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 73; BDBM3856; CHEMBL358384; SCHEMBL7975682; 1-phenyl-1H-1,3-benzodiazole-5-carbaldehyde
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
6-Chloro-1-phenylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 78; BDBM3861; CHEMBL153328; SCHEMBL7986437; 1-Phenyl-6-chloro-1H-benzoimidazole; 6-chloro-1-phenyl-1H-1,3-benzodiazole
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 84
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Investigative | Compound Info | ||
| Synonyms |
BDBM3867; CHEMBL153527; SCHEMBL17691570; 7-Methyl-1-phenyl-1H-benzimidazole; 7-methyl-1-phenyl-1H-1,3-benzodiazole
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9p
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Investigative | Compound Info | ||
| Synonyms |
BDBM4198; CHEMBL323017; 3-(2,6-Dichlorophenyl)-7-[(4-methoxyphenyl)amino]-1-methyl-1,8-naphthyridin-2(1H)-one; 3-(2,6-dichlorophenyl)-7-[(4-methoxyphenyl)amino]-1-methyl-1,2-dihydro-1,8-naphthyridin-2-one
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
1-Phenylbenzimidazol-4-ol
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Investigative | Compound Info | ||
| Synonyms |
4-Hydroxy-1-phenylbenzimidazole Hydrochloride; 1-Phenylbenzimidazole deriv. 56; 1-Phenylbenzimidazole 4; CHEMBL75964; BDBM3839; SCHEMBL7986692; 1-Phenyl-1H-benzimidazole-4-ol; 1-phenyl-1H-1,3-benzodiazol-4-ol
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
4-Phenyl-2,3-dihydro-1H-1,5-benzodiazepine
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Investigative | Compound Info | ||
| Synonyms |
1H-1,5-Benzodiazepine,2,3-dihydro-4-phenyl-; 1-Phenylbenzimidazole Analog 7; BDBM3790; CHEMBL358447; CTK4E5480; DTXSID70377993; KS-00001OQ3; ZINC6732099; MFCD06245350; AKOS005254938; MCULE-2529152208; 2,3-Dihydro-4-phenyl-1H-1,5-benzodiazepine; 4-phenyl-2,3-dihydro-1h-benzo-1,5-diazepine; 2-ETHYL-2-METHYLACETOACETICACIDETHYLESTER; (E)-4-phenyl-2,3-dihydro-1H-benzo[b][1,4]diazepine
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-(1H-Benzimidazol-1-yl)Benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 36; BDBM3819; CHEMBL356027; SCHEMBL8188627; 1-(3-Cyanophenyl)-1H-benzimidazole; ZINC13782606; DA-07620; 3-(1H-1,3-benzodiazol-1-yl)benzonitrile; FT-0740915
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 85
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Investigative | Compound Info | ||
| Synonyms |
BDBM3868; CHEMBL153526; 7-methoxy-1-phenyl-1H-1,3-benzodiazole
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| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
6-Methyl-1-phenylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 75; BDBM3858; CHEMBL347777; SCHEMBL13993884; 6-methyl-1-phenyl-1H-1,3-benzodiazole; 6-Methyl-1-phenylbenzimidazole Hydrochloride
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 26
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Investigative | Compound Info | ||
| Synonyms |
BDBM3937; CHEMBL309270; 1-Phenyl-1H-benzimidazole-5-ol dimethylthiocarbamate; N,N-dimethyl-1-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]methanethioamide
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-(2-Methylphenyl)benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 12; BDBM3795; CHEMBL153145; SCHEMBL12138417; 1-(2-Methylphenyl)-1H-benzimidazole; 1-(2-methylphenyl)-1H-1,3-benzodiazole
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-(3-Methylphenyl)-3-[4-(3-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4103605; BDBM50238308
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
2-[2-Methoxy-4-(7-methyl-4-oxo-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-2-yl)phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597990; BDBM50307261; AKOS000599737; MCULE-4038640465
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[10] | |||
| Compound Name |
1-(2-Methoxyphenyl)-1H-benzoimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 13; 1-(2-Methoxy-phenyl)-1H-benzoimidazole; BDBM3796; CHEMBL345775; CTK5D9461; DTXSID10416153; ZINC13782596; 1H-Benzimidazole,1-(2-methoxyphenyl)-; SC-63505; 1-(2-methoxyphenyl)-1h-benzo[d]imidazole; 1-(2-methoxyphenyl)-1H-1,3-benzodiazole; 1-(2-Methoxyphenyl)benzimidazole Hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Methyl 20-methoxy-3,10-dioxo-12-oxapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-1(13),2(11),4,6,8,14,16,18,20-nonaene-21-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL201840; BDBM50178493; 5-methoxy-7,12-dioxo-7,12-dihydro-dinaphtho[1,2-b;2'',3''-d]furan-6-carboxylic acid methyl ester
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
1-Phenyl-1H-benzoimidazol-2-ylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-phenyl-1H-1,3-benzodiazol-2-amine; 1-phenylbenzimidazol-2-amine; 1-Phenyl-1h-benzimidazol-2-amine; 1-PHENYL-1H-BENZO[D]IMIDAZOL-2-AMINE; 1-Phenylbenzimidazole deriv. 53; 2-amino-N-phenylbenzimidazole; 2-amino-1-phenylbenzimidazole; 2-amino-3-phenylbenzimidazole; 2-amino-N-phenyl-benzimidazole; BDBM3836; CHEMBL356228; SCHEMBL2309144; CTK4I6894; DTXSID60378277; 1-Phenyl-1H-benzimidazole-2-amine; ZINC13782609; AKOS000365315; MB04242; MCULE-9998473641; NE13443; 1-phenyl-1h-benzo[d]imidazol-2-ylamine; CS-0117097; EN300-43667; AB00999088-01; Z449369006
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 87
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3870; CHEMBL150899; 7-chloro-1-phenyl-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
4-Benzoimidazol-1-yl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(benzimidazol-1-yl)benzamide; 1-Phenylbenzimidazole deriv. 44; BDBM3827; CHEMBL345730; SCHEMBL20604030; CTK4E8399; DTXSID70416159; 4-benzo[d]imidazol-1-ylbenzamide; 4-(1H-benzimidazol-1-yl)benzamide; 1-(4-Carboxamidophenyl)benzimidazole; MFCD08437159; ZINC13782573; 4-(1H-Benzoimidazole-1-yl)benzamide; Benzamide,4-(1H-benzimidazol-1-yl)-; 4-(1H-1,3-benzodiazol-1-yl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
4-(1H-1,3-Benzodiazol-1-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(1H-benzimidazol-1-yl)benzoic acid; 4-(benzimidazol-1-yl)benzoic acid; 1-Phenylbenzimidazole deriv. 42; BDBM3825; CHEMBL345546; SCHEMBL1816262; CTK7I7990; HMS1749E10; ZINC3888400; AKOS000260665; CCG-291145; MCULE-3936533459; NE62360; 4-(1H-Benzoimidazole-1-yl)benzoic acid; EN300-13040; SR-01000068157; SR-01000068157-1; Z89271000
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenyl-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-phenylindole; 1H-Indole, 1-phenyl-; N-phenylindole; 1H-Indole, phenyl-; phenylindol; Indole, phenyl-; PubChem23692; 1H-Indole,1-phenyl-; SCHEMBL170890; BDBM3791; CHEMBL149746; 1-Phenylbenzimidazole deriv. 8; CTK0H3555; KS-00000MCW; DTXSID80185041; ACN-P000828; ZINC3083155; ANW-72258; MFCD00123280; AKOS006271861; CS-W006833; DS-2622; MP-1565; QC-9729; AC-17817; AK-45364; AB0052514; DB-005754; FT-0646940; FT-0698211; P2503; Z4239; A810206
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Methyl-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 63; BDBM3846; CHEMBL152934; SCHEMBL7986978; 5-methyl-1-phenyl-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 81
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3864; CHEMBL356679; 1-phenyl-1H-1,3-benzodiazole-6-carboxamide
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|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 32
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3943; CHEMBL310243; SCHEMBL7991043; 4-bromo-5-allyloxy-1-phenylbenzimidazole; 4-bromo-1-phenyl-5-(prop-2-en-1-yloxy)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
6-Methoxy-3-phenylbenzimidazole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 40; CHEMBL80171; BDBM3951; SCHEMBL7986304; 5-methoxy-1-phenylbenzimidazole-6-carboxylic acid; 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4194; CHEMBL107372; 1-Methyl-7-amino-3-(2,6-dichlorophenyl)-1,8-naphthyridine-2(1H)-one; 7-Amino-3-(2,6-dichlorophenyl)-1-methyl-1,8-naphthyridin-2(1H)-one; 7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydro-1,8-naphthyridin-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
1,6-Naphthyridine 45
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM6173; CHEMBL189628
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||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
3-(Benzimidazol-1-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 35; BDBM3818; CHEMBL151956; SCHEMBL7986951; 1-(3-formylphenyl)benzimidazole; AKOS013256528; 3-(1H-1,3-benzodiazol-1-yl)benzaldehyde
Click to Show/Hide
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||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 18
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3801; CHEMBL153812; SCHEMBL12822399; 2-(1H-benzimidazol-1-yl)benzamide; ZINC13782600; MCULE-8424588934; 2-(1H-1,3-benzodiazol-1-yl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Ethoxy-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 7; CHEMBL77407; BDBM3918; SCHEMBL7986395; 5-Ethoxy-1-phenyl-1H-benzimidazole; 5-ethoxy-1-phenyl-1H-1,3-benzodiazole; 5-ethoxy-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-(3-Bromophenyl)-3-[4-(3-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079338; BDBM50238319
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 79
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3862; CHEMBL149401; AKOS017555170; 1-phenyl-1H-1,3-benzodiazole-6-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
4,5-Dimethoxy-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 30; CHEMBL80558; BDBM3941; SCHEMBL7989444; 4,5-dimethoxy-1-phenyl-1H-1,3-benzodiazole; 4,5-dimethoxy-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Methyl 6-methoxy-3-phenylbenzimidazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 42; BDBM3953; CHEMBL311574; SCHEMBL7993243; methyl 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-carboxylate; methyl 5-methoxy-1-phenylbenzimidazole-6-carboxylate hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9h
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4196; CHEMBL104532; 3-(2,6-Dichlorophenyl)-1-methyl-7-[[3-(4-methylpiperazinyl)propyl]amino]-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 90
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3873; CHEMBL150934; 1-phenyl-1H-1,3-benzodiazole-7-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-[5-Amino-4-(1H-indole-2-carbonyl)pyrazol-1-yl]-1,3-dihydrobenzimidazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3952373; BDBM50197688
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
2-(Benzimidazol-1-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 16; 2-Benzoimidazol-1-yl-benzoic acid; Oprea1_459441; BDBM3799; CHEMBL152521; SCHEMBL2810948; ZINC86654; AKOS000260667; MCULE-4229145757; 2-(1H-1,3-benzodiazol-1-yl)benzoic acid
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-(2-Benzoimidazol-1-yl-phenyl)-ethanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 21; BDBM3804; CHEMBL153477; ZINC13782601; AKOS000221178; DA-31498; FT-0760182; 1-[2-(1H-1,3-benzodiazol-1-yl)phenyl]ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
6-(2,6-Dichlorophenyl)-2-(dimethylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299347; 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 28; BDBM3061; SCHEMBL5761783; 2-(Dimethylamino)-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidine-7(8H)-one; 6-(2,6-dichlorophenyl)-2-(dimethylamino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one; 6-(2,6-Dichlorophenyl)-2-dimethylamino-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
Methyl 4-(benzimidazol-1-yl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 43; BDBM3826; CHEMBL434312; SCHEMBL1812955; ZINC13782572; methyl 4-(1H-benzimidazol-1-yl)benzoate; DB-101314; methyl 4-(1H-1,3-benzodiazol-1-yl)benzoate; 4-(1H-Benzimidazole-1-yl)benzoic acid methyl ester
Click to Show/Hide
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||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
3,4-Dihydro-1,6-naphthyridine analogue 53
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM6186; CHEMBL192668; ZINC13647891
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 33
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3944; CHEMBL307817; 4-Allyl-5-hydroxy-1-phenylbenzimidazole; 1-phenyl-4-(prop-2-en-1-yl)-1H-1,3-benzodiazol-5-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2-Benzoimidazol-1-yl-phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(benzimidazol-1-yl)phenol; Phenol, 1H-benzimidazolyl-; 2-(1H-Benzimidazol-1-yl)phenol; 1-Phenylbenzimidazole deriv. 14; 2-(1H-Benzo[d]imidazol-1-yl)phenol; ACMC-20lrg8; SCHEMBL56852; 2-benzo[d]imidazol-1-ylphenol; BDBM3797; CHEMBL358240; CTK2I9137; 2-hydroxyphenyl-1h-benz-imidazole; DTXSID801001954; ZINC13782597; AKOS013758625; 2-(1H-1,3-benzodiazol-1-yl)phenol; DA-28816; FT-0703378; 3-(1-(2-Chlorophenyl)ethyl)pentane-2,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-(2-Fluoro-5-methylphenyl)-3-[4-(3-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4074713; BDBM50238293
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
3,4-Dihydro-1,6-naphthyridine analogue 48
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BDBM6181; CHEMBL188431
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
Anilinoquinazoline deriv. 31
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BDBM4648; CHEMBL151948; N-[4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-quinazolinyl]-2-methoxyacetamide hydrochloride; N-{4-[(4-chloro-2-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}-2-methoxyacetamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9q
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4199; CHEMBL106379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
1-Pyridin-3-ylbenzimidazole
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
N-(3-pyridinyl)benzimidazole; 1-Phenylbenzimidazole deriv. 37; BDBM3820; CHEMBL153571; SCHEMBL4106400; 1-(3-Pyridyl)-1H-benzoimidazole; 1-(pyridin-3-yl)-1H-1,3-benzodiazole; 1-(Pyridin-3-yl)-1H-benzo[d]imidazole; DA-07627; FT-0705645
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Nitro-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-nitro-1-phenyl-1H-benzimidazole; 1H-Benzimidazole, 5-nitro-1-phenyl-; MLS000553360; 5-Nitro-1-phenyl-1H-benzoimidazole; Cambridge id 5659846; Oprea1_293142; Oprea1_793806; BDBM3853; CHEMBL153208; SCHEMBL3342620; CTK0E8374; 1-Phenylbenzimidazole deriv. 70; DTXSID00353386; HMS2558A08; ZINC174449; ALBB-023827; CCG-46050; MFCD00179556; STK003475; AKOS000562552; MCULE-8383436610; 5-nitro-1-phenyl-1H-benzo[d]imidazole; 5-nitro-1-phenyl-1H-1,3-benzodiazole; SMR000175668; ST088191; R2454; AB00092174-01; SR-01000439600; SR-01000439600-1; SR-01000439600-2
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-Methyl-1-phenyl-1H-benzo[d]imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-methyl-1-phenyl-1H-benzimidazole; 2-methyl-1-phenylbenzimidazole; 2-Methyl-1-phenyl-1H-benzoimidazole; 2-methyl-1-phenyl-1H-1,3-benzodiazole; 1-phenyl-2-methylbenzimidazole; 1H-benzimidazole, 2-methyl-1-phenyl-; CBMicro_004833; Cambridge id 5119817; 1-phenyl-2methylbenzimidazole; MLS000104811; SCHEMBL540947; BDBM3834; CHEMBL150809; CTK4C5807; ZINC90644; 1-Phenylbenzimidazole deriv. 51; DTXSID90348645; HMS1607G17; HMS2324O15; SMSF0003517; 1-Phenyl-2-methyl-1H-benzimidazole; 7391AA; ANW-73124; BBL003863; MFCD00227220; STK396328; 1H-Benzimidazole,2-methyl-1-phenyl-; AKOS000622868; CB06807; CCG-103103; MCULE-2162222590; SMR000054744; BIM-0004997.P001; EU-0066724; ST50036707; T7416; SR-01000389013; SR-01000389013-1; BRD-K21465339-001-09-8; Z56754526
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1,6-Naphthyridine 46
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM6174; CHEMBL365133
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
4-(1H-1,3-Benzimidazol-1-yl)benzenecarbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(benzimidazol-1-yl)benzaldehyde; 4-(1h-benzimidazol-1-yl)benzaldehyde; 4-Benzoimidazol-1-yl-benzaldehyde; 4-(1H-Benzo[d]imidazol-1-yl)benzaldehyde; 4-(1H-1,3-benzodiazol-1-yl)benzaldehyde; 4-benzimidazolylbenzaldehyde; BDBM3831; CHEMBL153512; SCHEMBL2568999; CTK7H9430; 1-Phenylbenzimidazole deriv. 48; 4-(1-benzimidazolyl)benzaldehyde; DTXSID90353279; ZINC168834; KS-00001VY4; 2758AF; MFCD03425762; SBB018175; AKOS000260443; 1-(4-Formylphenyl)-1H-benzoimidazole; MCULE-9808897711; VZ27641; DB-057208; FT-0642172; ST50289670; Z-0322; 3T-0322; A843569; SR-01000065925; J-513212; SR-01000065925-1; 4-(1H-1,3-benzimidazol-1-yl)benzenecarbaldehyde, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-Phenylimidazo[4,5-b]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Phenyl-3H-imidazo[4,5-b]pyridine; 1-Phenylbenzimidazole deriv. 93; BDBM3876; CHEMBL153110; SCHEMBL1858815; CTK2D8117; DTXSID60416163; ZINC13782593; 3h-imidazo[4,5-b]pyridine,3-phenyl-; 3H-Imidazo[4,5-b]pyridine, 3-phenyl-; 1-Phenyl-1H-imidazo[5,4-b]pyridine Dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 34
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3817; CHEMBL155093; ZINC13782568; AKOS017719293; DA-25486; 1-[3-(1H-1,3-benzodiazol-1-yl)phenyl]ethan-1-one
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 83
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3866; CHEMBL152995; SCHEMBL19848656; 1-phenyl-1H-1,3-benzodiazol-6-amine; 6-Amino-1-phenylbenzimidazole Dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-(3-Chlorophenyl)benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 28; BDBM3811; CHEMBL150573; 1-(3-Chlorophenyl)-1H-benzoimidazole; 1-(3-chlorophenyl)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
6-(2,6-Dichlorophenyl)-2-hydroxy-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 20; BDBM3053; CHEMBL109725; SCHEMBL5763230; ZINC13780919; 6-(2,6-dichlorophenyl)-8-methyl-1H-pyrido[2,3-d]pyrimidine-2,7-dione; DA-36906; 2-Hydroxy-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidine-7(8H)-one; 6-(2,6-dichlorophenyl)-2-hydroxy-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
3-Substituted indolin-2-one 16d
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4898; CHEMBL150177
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
1-Phenyl-1H-indazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-phenylindazole; phenyl 1h indazole; NSC195336; SCHEMBL729956; BDBM3792; CHEMBL151537; 1-Phenylbenzimidazole deriv. 9; DTXSID50307854; ZINC402178; AKOS006275470; MB00797; MCULE-1676225437; NSC-195336; AC-17963; DA-17343; FT-0691149
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-(2-Chlorophenyl)benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 15; BDBM3798; CHEMBL153417; SCHEMBL7211112; 1-(2-Chlorophenyl)-1H-benzoimidazole; 1-(2-chlorophenyl)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 92
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3875; CHEMBL357368; 7-Amino-1-phenyl-1H-benzimidazole; 1-phenyl-1H-1,3-benzodiazol-7-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9n
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4197; CHEMBL420473; 3-(2,6-dichlorophenyl)-1-methyl-7-(phenylamino)-1,2-dihydro-1,8-naphthyridin-2-one; 3-(2,6-Dichlorophenyl)-1-methyl-7-(phenylamino)-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 19
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL51573; BDBM3052; SCHEMBL5763098; 2,8-Dimethyl-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidine-7(8H)-one; 6-(2,6-dichlorophenyl)-2,8-dimethyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
3,4-Dihydro-1,6-naphthyridine analogue 50
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM6183; CHEMBL190443; ZINC14945363
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 86
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3869; CHEMBL357347; 1-phenyl-1H-1,3-benzodiazol-7-ol
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
1-Phenyl-5-propan-2-yloxybenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 9; CHEMBL79328; BDBM3920; SCHEMBL7975892; 5-Isopropoxy-1-phenyl-1H-benzimidazole; 5-isopropoxy-1-phenylbenzimidazole hydrochloride; 1-phenyl-5-(propan-2-yloxy)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
1-(4-Nitrophenyl)-1H-benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(4-nitrophenyl)-1H-1,3-benzodiazole; SBB024797; 1H-Benzimidazole, 1-(4-nitrophenyl)-; (4-nitrophenyl)benzimidazole; 1-(4-nitrophenyl)benzimidazole; 1-(p-nitrophenyl)benzimidazole; BDBM3828; CHEMBL345970; SCHEMBL3834819; CTK0J6358; 1-Phenylbenzimidazole deriv. 45; DTXSID70401969; KS-000023RT; ZINC4676136; MFCD03937392; STK120236; 1-(4-Nitrophenyl)-1H-benzoimidazole; AKOS005167722; CF-0282; MCULE-8275445926; ST45127986
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Benzoyl-1H-benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1H-Benzimidazole, 1-benzoyl-; benzimidazol-1-yl(phenyl)methanone; N-benzoylbenzimidazole; benzimidazolyl phenyl ketone; Cambridge id 5172830; TimTec1_000806; CBDivE_006382; BDBM3788; CHEMBL153600; SCHEMBL3477048; 1-Phenylbenzimidazole deriv. 5; 1-benzoyl-1H-1,3-benzodiazole; CTK2B7068; DTXSID10351818; HMS1536E14; HMS3448I12; ZINC101715; STK014967; 1H-benzimidazol-1-yl(phenyl)methanone; AKOS000506064; MCULE-1764470572; ST010700; (1H-Benzo[d]imidazol-1-yl)(phenyl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-(2,6-Dichlorophenyl)-7-(dimethylamino)-1-methyl-1,6-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridin-2(1H)-one deriv. 7c; BDBM4170; CHEMBL108170; SCHEMBL6638893; 1-Methyl-7-(dimethylamino)-3-(2,6-dichlorophenyl)-1,6-naphthyridine-2(1H)-one; 3-(2,6-dichlorophenyl)-7-(dimethylamino)-1-methyl-1,2-dihydro-1,6-naphthyridin-2-one; 3-(2,6-Dichlorophenyl)-7-(dimethylamino)-1-methyl-1,6-naphthyridin-2(1H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
5-Methoxy-6-methyl-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 38; CHEMBL77712; BDBM3949; SCHEMBL7986240; 1-Phenyl-5-methoxy-6-methyl-1H-benzimidazole; 5-methoxy-6-methyl-1-phenyl-1H-1,3-benzodiazole; 5-methoxy-6-methyl-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
4-Methoxy-1-phenylbenzimidazol-5-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 29; BDBM3940; CHEMBL308385; SCHEMBL7975839; 5-hydroxy-4-methoxy-1-phenylbenzimidazole; 4-methoxy-1-phenyl-1H-1,3-benzodiazol-5-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3,4-Dihydro-1,6-naphthyridine analogue 51
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM6184; CHEMBL363304
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
4-(1H-1,3-Benzodiazol-1-yl)benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(1H-benzimidazol-1-yl)Benzonitrile; 1-Phenylbenzimidazole deriv. 49; 4-(benzimidazol-1-yl)benzonitrile; 1-(4-cyanophenyl)benzimidazole; BDBM3832; CHEMBL356237; SCHEMBL2039920; CTK7C7845; 4-benzimidazolylbenzenecarbonitrile; 1-(4-Cyanophenyl)-1H-benzimidazole; STL412451; ZINC13782574; AKOS000222376; CCG-291204; MCULE-6102674544; NE19880; DA-07619; FT-0723696; ST45255832; EN300-59571
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 34
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75637; BDBM3945; 4,5-Dihydro-5-methyl-1-phenylfuro[3,2-e]benzimidazole Hydrochloride; 11-methyl-5-phenyl-10-oxa-3,5-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,3,6,8-tetraene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-Substituted indolin-2-one 16c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4897; CHEMBL149073
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
3-(1h-Benzo[d]imidazol-1-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(benzimidazol-1-yl)benzoic acid; 1-Phenylbenzimidazole deriv. 29; BDBM3812; CHEMBL150575; SCHEMBL1354830; ZINC13782603; AKOS013257353; 3-(1H-1,3-benzodiazol-1-yl)benzoic acid; W-3719
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 59
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3842; CHEMBL154978; methyl 1-phenyl-1H-1,3-benzodiazole-4-carboxylate; Methyl 1-Phenylbenzimidazole-4-carboxylate Hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-[9-(4-Amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-N-(4-morpholin-4-ylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL395080; BDBM50218700
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 22
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3805; CHEMBL150790; AKOS000260396; 2-(1H-1,3-benzodiazol-1-yl)benzaldehyde
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-Substituted indolin-2-one 11b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SU5402 analog 11b; BDBM4888; CHEMBL435227; SCHEMBL4409949
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
4-Chloro-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 57; BDBM3840; CHEMBL348189; 4-chloro-1-phenyl-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
4-Nitro-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 61; BDBM3844; CHEMBL150579; 4-nitro-1-phenyl-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4195; CHEMBL107247; 3-(2,6-Dichlorophenyl)-7-[[3-(diethylamino)propyl]amino]-1-methyl-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
4-Methoxy-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-methoxy-1-phenylbenzimidazole hydrochloride; 1-Phenylbenzimidazole deriv. 55; BDBM3838; CHEMBL149458; SCHEMBL7975806; ZINC13782576; 4-methoxy-1-phenyl-1H-1,3-benzodiazole; DA-39252; FT-0717154
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
ClC1=C(C(=C(C=C1OC)OC)Cl)NC(N(C)C1=CC(=NC=N1)NC1=C(C=CC=C1)NC(C(=C)F)=O)=O
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3968830; SCHEMBL16665375; BDBM249397; US9434697, 110
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 54
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3837; CHEMBL149635; SCHEMBL17691571; 4-methyl-1-phenyl-1H-1,3-benzodiazole; 4-Methyl-1-phenylbenzimidazole Hydrochloride
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
PD089828 analog 12
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49658; BDBM4831; 1-{2-amino-6-[3,5-bis(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-yl}-3-tert-butylurea; N-[2-Amino-6-[3,5-bis(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidine-7-yl]-N'-tert-butylurea
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
Methyl 1-phenylbenzoimidazole-6-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Methyl 1-phenyl-1H-benzo[d]imidazole-6-carboxylate; methyl 3-phenylbenzimidazole-5-carboxylate; 1-Phenylbenzimidazole deriv. 80; BDBM3863; CHEMBL359055; SCHEMBL7975748; MFCD13195708; ZINC13782586; AKOS015840723; V4431; K-6254; methyl 1-phenyl-1H-1,3-benzodiazole-6-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl)-1H-pyrazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290746; SCHEMBL14097139; BDBM50331629
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[19] | |||
| Compound Name |
1-(3-Methylphenyl)benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(3-Methylphenyl)-1H-benzimidazole; 1-Phenylbenzimidazole deriv. 25; BDBM3808; CHEMBL346000; SCHEMBL16147463; ZINC13782562; 1-(3-methylphenyl)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-Benzoimidazol-1-yl-phenylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(benzimidazol-1-yl)aniline; 2-(1H-benzimidazol-1-yl)aniline; 2-benzimidazolylphenylamine; 1-Phenylbenzimidazole deriv. 20; 2-(1H-benzo[d]imidazol-1-yl)benzenamine; N-(o-aminophenyl)benzimidazole; BDBM3803; CHEMBL153365; SCHEMBL4944401; CTK4F7532; DTXSID70416154; 2-benzo[d]imidazol-1-ylphenylamine; ZINC2538825; 1-(2-Aminophenyl)-1H-benzimidazole; BBL040094; MFCD04971067; SBB022486; STK349843; AKOS000137260; 2-(1H-Benzo[d]imidazol-1-yl)aniline; CCG-317179; MCULE-4622008356; 2-(1H-1,3-benzodiazol-1-yl)aniline; DA-28817; ST070803; FT-0712231
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(thiophen-3-ylmethoxy)quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Anilinoquinazoline deriv. 25; BDBM4642; CHEMBL151067; SCHEMBL7454326; N-(2-Fluoro-4-chlorophenyl)-6-methoxy-7-(3-thienylmethoxy)quinazoline-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
1-Pyridin-4-yl-1H-benzoimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-pyridin-4-ylbenzimidazole; 1-Phenylbenzimidazole deriv. 50; 1-(4-pyridyl)benzimidazole; SCHEMBL900306; BDBM3833; CHEMBL358429; ZINC13782575; 1-(pyridin-4-yl)-1H-1,3-benzodiazole; DA-07978; FT-0706484
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Methyl 3,10-dioxo-20-propoxy-12-oxapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-1(13),2(11),4,6,8,14,16,18,20-nonaene-21-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202216; BDBM50178496; 7,12-dioxo-5-propoxy-7,12-dihydro-dinaphtho[1,2-b;2'',3''-d]furan-6-carboxylic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
1-(4-Methylphenyl)-1H-benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(4-methylphenyl)-1H-1,3-benzodiazole; Enamine_002933; 1-(4-methylphenyl)benzimidazole; 1-p-Tolyl-1H-benzimidazole; BDBM3821; CHEMBL347769; 1-(p-tolyl)-1H-benzoimidazole; SCHEMBL10053918; CTK2F1578; 1-Phenylbenzimidazole deriv. 38; DTXSID20364237; HMS1402F07; ZINC1470611; 1H-Benzimidazole, 1-(4-methylphenyl)-; SR-01000032590; SR-01000032590-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
4-Bromo-1-phenylbenzimidazol-5-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-Bromo-5-Hydroxy-1-phenylbenzimidazole hydrochloride; 5-Substituted 1-Phenylbenzimidazole 31; CHEMBL76839; BDBM3942; SCHEMBL7989967; 4-bromo-1-phenyl-1H-1,3-benzodiazol-5-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
6-Methoxy-1-phenyl-1H-benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-methoxy-1-phenylbenzimidazole; CBMicro_030429; MLS000077152; BDBM3859; CHEMBL356169; cid_652633; SCHEMBL3063006; 1-phenyl-6-methoxybenzimid-azole; 1-Phenylbenzimidazole deriv. 76; HMS2383F20; ZINC361259; 6-Methoxy-1-phenyl-1H-benzoimidazole; AKOS002783908; 6-methoxy-1-phenyl-1H-1,3-benzodiazole; SMR000001075; BIM-0030561.P001
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 62
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3845; CHEMBL405050; 1-phenyl-1H-1,3-benzodiazol-4-amine; 4-Amino-1-phenylbenzimidazole Hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenyl-1H-benzo[d]imidazol-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-phenyl-1H-benzimidazol-2-one; 2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl-; 1-Phenylbenzimidazolin-2-one; 1-phenyl-1,3-dihydro-benzoimidazol-2-one; 2-Benzimidazolinone, 1-phenyl-; 1,3-Dihydro-1-phenyl-2H-benzimidazol-2-one; 1-Phenylbenzimidazole deriv. 52; 1-Phenylbenzimidazolon; 1-Phenyl-2-benzimidazolinone; hydroxyphenyl 1h benzimidazole; SCHEMBL699273; BDBM3835; CHEMBL150912; SCHEMBL12252055; CTK4C5712; KS-00000QXH; 1-Phenyl-1H-benzoimidazol-2-ol; 1-Phenyl-2(3H)-benzimidazolone; DTXSID20163888; MFCD01658803; ZINC13782608; 1-phenyl-1H-1,3-benzodiazol-2-ol; AKOS004910623; 1-Phenyl-1H-benzimidazole-2(3H)-one; CS-W021364; FS-3786; 1-Phenyl-1,3-dihydrobenzoimidazol-2-one; 1-phenyl-2,3-dihydro-benzimidazol-2-one; AK126036; DA-10077; FT-0737557; Z4181; 2H-Benzimidazol-2-one,1,3-dihydro-1-phenyl-; M-8491; 1-Phenyl-1,3-dihydro-2H-benzimidazol-2-one #; 1-phenyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
(Z)-3-(2,4-Dimethyl-5-((2-oxo-6-phenylindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SU 16F; CHEMBL149201; SU-16F; 3-substituted indolin-2-one 16f; BDBM4900; SCHEMBL4408682; ZINC3834020; AKOS015994588; ES-0059; NCGC00370874-01; HY-108628; CS-0029344; J-015830; PDGFR Tyrosine Kinase Inhibitor VII - CAS 251356-45-3
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
1-Phenylbenzimidazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 60; BDBM3843; CHEMBL149573; 1-phenyl-1H-1,3-benzodiazole-4-carboxamide; 1-Phenylbenzimidazole-4-carboxamide Hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Methoxy-1-phenylbenzimidazol-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 28; CHEMBL77412; BDBM3939; SCHEMBL7975887; ZINC13798306; 4-hydroxy-5-methoxy-1-phenylbenzimidazole; 5-Methoxy-1-phenyl-1H-benzimidazole-4-ol; 5-methoxy-1-phenyl-1H-1,3-benzodiazol-4-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-[4-(3-Methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065800; BDBM50238302
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 58
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3841; CHEMBL150765; 1-phenyl-1H-1,3-benzodiazole-4-carboxylic acid; 1-Phenylbenzimidazole-4-carboxylic Acid Hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
6-Methyl-1-phenylbenzimidazol-5-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 39; BDBM3950; CHEMBL311913; SCHEMBL7989577; 1-Phenyl-6-methyl-1H-benzimidazole-5-ol; 6-methyl-1-phenyl-1H-1,3-benzodiazol-5-ol; 5-hydroxy-6-methyl-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 89
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3872; CHEMBL154750; methyl 1-phenyl-1H-1,3-benzodiazole-7-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenylbenzimidazole deriv. 30
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3813; CHEMBL358241; ethyl 3-(1H-1,3-benzodiazol-1-yl)benzoate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-(3-Methoxyphenyl)-1H-benzoimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(3-methoxyphenyl)benzimidazole; 1-Phenylbenzimidazole deriv. 26; BDBM3809; CHEMBL346611; SCHEMBL18280702; CTK5D9460; DTXSID90416156; ZINC13782563; 1H-Benzimidazole,1-(3-methoxyphenyl)-; 1-(3-methoxyphenyl)-1h-benzo[d]imidazole; 1-(3-methoxyphenyl)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
3,4-Dihydro-1,6-naphthyridine analogue 52
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM6185; CHEMBL191372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
5-Chloro-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylbenzimidazole deriv. 66; 5-chloro-1-phenyl-1H-1,3-benzodiazole; BDBM3849; CHEMBL436455; SCHEMBL6756590; ZINC405539
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[2] | |||
| Compound Name |
N-(2,4-Difluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(2,4-difluorophenyl)-6,7-dimethoxy-4-quinazolinamine; Anilinoquinazoline deriv. 8; Oprea1_400575; BDBM4625; CHEMBL346200; KS-00002ZTK; ZINC1386780; AKOS005078510; MCULE-2267071705; 11N-061; N-(2,4-Difluorophenyl)-6,7-dimethoxyquinazoline-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[15] | |||
| Compound Name |
N=1C=2C(C(=O)NC)=CC=CC=2NC=1C(C1=CC=2)=Nnc1=CC=2C1=CC=C(O)C=C1OC
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL5249604; CHEMBL3976302
Click to Show/Hide
|
||||
| Activity |
Ki = 70000 nM
|
[21] | |||
| Compound Name |
6-Phenyl-1H-indazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1H-Indazole, 6-phenyl-; CHEMBL4170644; PubChem22855; SCHEMBL2460902; DTXSID40717100; BDBM50280102; MFCD11109933; ZINC75629442; AKOS006306916; AS-57658; QC-11274; DB-023244; AM20080840; FT-0746234
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[22] | |||
| Compound Name |
Chembl4163123
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50280106
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[22] | |||
| Compound Name |
6-Pyridin-3-YL-1H-indazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-(pyridin-3-yl)-1h-indazole; CHEMBL4159996; 1H-Indazole,6-(3-pyridinyl)-; SCHEMBL16935421; CTK5G0269; DTXSID30696293; 6027AH; BDBM50280103; ZINC64033491; AKOS006295679; AB18777; DB-077436; FT-0751523
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[22] | |||
| Compound Name |
Coc1=CC(O)=CC=C1C1=CC=C(C(=NN2)C=3NC4=CC=C(C=C4N=3)N(C)C)C2=C1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL5251093; CHEMBL3915814
Click to Show/Hide
|
||||
| Activity |
Ki = 91000 nM
|
[21] | |||
| Compound Name |
N-(5-Chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzodioxole deriv. 19; BDBM6210; CHEMBL369360; N-(5-chloro-2H-1,3-benzodioxol-4-yl)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
N-(4-Chloro-2-fluorophenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Anilinoquinazoline deriv. 14; BDBM4631; CHEMBL148869; N-(2-Fluoro-4-chlorophenyl)-6,7-bis(2-methoxyethoxy)quinazoline-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
N-[4-(2-Fluoro-5-hydroxy-4-methylanilino)-6-methoxyquinazolin-7-yl]-2-methoxyacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Anilinoquinazoline deriv. 33; BDBM4650; CHEMBL151015; N-{4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6-methoxyquinazolin-7-yl}-2-methoxyacetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
Chembl4173432
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50280107
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-ethylbenzo[de]isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2407517; BDBM50437562
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-hexadecylbenzo[de]isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2407635; BDBM50437557
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Gefitinib Impurity 10; CHEMBL301018; Anilinoquinazoline deriv. 9; BDBM4626; SCHEMBL2099106; ZINC16978; AKOS002350953; MCULE-5998118475; DS-015821; N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
N-(5-Chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Chlorobenzodioxole deriv. 27; AZD0530 analogue 34; BDBM6218; CHEMBL170984; SCHEMBL3186214
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-methylbenzo[de]isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2407516; BDBM50437563
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-(4-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Anilinoquinazoline deriv. 3; Oprea1_804297; 4-Quinazolinamine,N-(4-chlorophenyl)-6,7-dimethoxy-; BDBM4620; CHEMBL147138; SCHEMBL5477771; ZINC1387036; MCULE-4942579265; AR-434/43382608; N-(4-Chlorophenyl)-6,7-dimethoxyquinazoline-4-amine; N-(4-chlorophenyl)-N-(6,7-dimethoxy-4-quinazolinyl)amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
2-Butyl-6-[2-[2-(dimethylamino)ethylamino]ethylamino]benzo[de]isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2407518; BDBM50437561
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[2-(triazol-1-yl)ethoxy]quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ZD-4190; ZD4190; SCHEMBL173259; BDBM4651; CHEMBL281872; BCP30854; ZINC1490292; HY-U00002; s6543; CS-6801; ZD 4190;ZD4190
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
N-(5-Chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Chlorobenzodioxole deriv. 28; BMCL182776 Compound 1; BDBM6219; CHEMBL169186; SCHEMBL3210014; DB07249; KX2-328; Q27096474
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
N-(2-Fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL150581; Anilinoquinazoline deriv. 2; BDBM4619; SCHEMBL5864529; DTXSID90877960; 6,7-DIMETHOXY-4-(O-FLUOROANILINO)-QUINAZOLINE; N-(2-Fluorophenyl)-6,7-dimethoxy-4-quinazolinylamine; N-(2-Fluorophenyl)-6,7-dimethoxyquinazoline-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
Chembl4276946
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GTPL9965; compound 3a [Pipionne et al, 2018]; 1-[5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl]ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-hexylbenzo[de]isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2407519; BDBM50437560
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 3 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(Z)-5-(4-(3-(3,5-Dimethylphenoxy)propoxy)-3-ethoxybenzylidene)-2-thioxoimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598601; BDBM50307262
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[26] | |||
| Compound Name |
Chembl4165338
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50280111
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[22] | |||
| Compound Name |
(Z)-5-(4-(3-(3,5-Dimethylphenoxy)propoxy)-3-(methoxymethyl)benzylidene)-2-thioxoimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597374; BDBM50307263
Click to Show/Hide
|
||||
| Activity |
IC50 = 3300000 nM
|
[26] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure-activity relationships for 5-substituted 1-phenylbenzimidazoles as selective inhibitors of the platelet-derived growth factor receptor. J Med Chem. 1999 Jul 1;42(13):2373-82. | ||||
| REF 2 | Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor. J Med Chem. 1998 Dec 31;41(27):5457-65. | ||||
| REF 3 | A novel series of 4-phenoxyquinolines: potent and highly selective inhibitors of PDGF receptor autophosphorylation. Bioorg Med Chem Lett. 1997 Dec 2;7(23):2935-40. | ||||
| REF 4 | Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and P... J Med Chem. 1999 Dec 16;42(25):5120-30. | ||||
| REF 5 | Synthesis and structure-activity relationships of 7-substituted 3-(2, 6-dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as selective inhibitors of pp60(c-src). J Med Chem. 2000 Aug 10;43(16):3134-47. | ||||
| REF 6 | Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors. J Med Chem. 2002 Mar 14;45(6):1300-12. | ||||
| REF 7 | Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2652-7. | ||||
| REF 8 | Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity. J Med Chem. 2001 Jun 7;44(12):1915-26. | ||||
| REF 9 | Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFRalpha) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs). J Med Chem. 2017 Jun 22;60(12):5099-5119. | ||||
| REF 10 | Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe. Eur J Med Chem. 2017 Sep 29;138:1053-1065. | ||||
| REF 11 | Naphthofuroquinone derivatives: inhibition of receptor tyrosine kinases. Bioorg Med Chem Lett. 2006 Feb;16(3):737-42. | ||||
| REF 12 | Synthesis and structure-activity relationships of soluble 7-substituted 3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-amines and related ureas as dual inhibitors of the fibroblast growth factor receptor-1 and vascular endothelial growth factor receptor-2 tyrosine kinases. J Med Chem. 2005 Jul 14;48(14):4628-53. | ||||
| REF 13 | Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor. J Med Chem. 2016 Dec 8;59(23):10586-10600. | ||||
| REF 14 | 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. J Med Chem. 1998 Aug 13;41(17):3276-92. | ||||
| REF 15 | Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J Med Chem. 1999 Dec 30;42(26):5369-89. | ||||
| REF 16 | Design, synthesis, and biological activity of 5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one-based potent and selective Chk-1 inhibitors. J Med Chem. 2007 Aug 23;50(17):4162-76. | ||||
| REF 17 | US patent application no. 9434697B2, Pyrimidine FGFR4 inhibitors | ||||
| REF 18 | Discovery and structure-activity studies of a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. Bioorg Med Chem Lett. 1997 Sep 23;7(18):2415-20. | ||||
| REF 19 | 5-amino-pyrazoles as potent and selective p38alpha inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6886-9. | ||||
| REF 20 | Novel inhibitor for fibroblast growth factor receptor tyrosine kinase. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4812-8. | ||||
| REF 21 | US patent application no. 6531491B1, Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | ||||
| REF 22 | Identification of an Indazole-Based Pharmacophore for the Inhibition of FGFR Kinases Using Fragment-Led de Novo Design. ACS Med Chem Lett. 2017 Nov 11;8(12):1264-1268. | ||||
| REF 23 | Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src. J Med Chem. 2004 Feb 12;47(4):871-87. | ||||
| REF 24 | Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs). Eur J Med Chem. 2013 Jul;65:477-86. | ||||
| REF 25 | N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK. Medchemcomm. 2018 Apr 12;9(6):963-968. | ||||
| REF 26 | Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening. J Med Chem. 2010 Feb 25;53(4):1662-72. | ||||
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