Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T46508 | Target Info | |||
| Target Name | Voltage-gated potassium channel (VGKC) | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | NO-GeName | ||||
| Biochemical Class | Voltage-gated ion channel | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 6 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
6-Methoxytryptamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(6-methoxy-1H-indol-3-yl)ethanamine; 3-(2-Aminoethyl)-6-methoxyindole; 1H-INDOLE-3-ETHANAMINE, 6-METHOXY-; 2-(6-Methoxy-1H-indol-3-yl)-ethylamine; 2-(2-Aminoethyl)-5-methoxyindole; CHEMBL337825; 1H-Indole-3-ethanamine,6-methoxy-; 6-Methoxytryptamine hydrochloride; 2-(6-methoxy-1H-indol-3-yl)ethylamine; 6-Methoxytryptamine, 99%; 2-(6-methoxyindol-3-yl)ethylamine; CBDivE_000653; EINECS 222-778-2; 6-methoxy tryptamine; PubChem24288; 6-MeOT; ChemDiv2_004125; Oprea1_535398; SCHEMBL379337; 6-Methoxytryptamine, free base; CTK4H5895; ZINC77360; DTXSID80189680; HMS1380L11; ALBB-021005; KS-000025XF; ANW-46721; BDBM50028124; MFCD00005663; PDSP1_001697; PDSP2_001680; SBB000286; STL281843; AKOS000265357; AB00465; CCG-112234; GS-3335; MCULE-1065608717; VZ30813; 6-Methoxytryptamine, analytical standard; IDI1_002840; NCGC00163351-01; SC-78655; AB0076679; DB-048919; A6266; EU-0011857; FT-0621205; ST45021221; W-6181; 610M364; 2-(6-METHOXY-1H-INDOL-3-YL)ETHAN-1-AMINE
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.91E+12 nM
|
[1] | |||
| Compound Name |
N1-(5-Chloro-6-methyl-2-pyridin-3-YL-pyrimidin-4-YL)-ethane-1,2-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL386028; SCHEMBL9999638; CTK7E9018; CCG-1349; BDBM50476059
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.20E+13 nM
|
[1] | |||
| Compound Name |
1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-phenoxyethanamine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218975; BDBM50476061
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.48E+13 nM
|
[1] | |||
| Compound Name |
Piperazine, 1-[2-[(4-chlorophenyl)sulfonyl]ethyl]-4-(phenylmethyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219249; Maybridge3_004133; Oprea1_730634; NPE159; CTK3B4388; DTXSID80384936; HMS1442L19; BDBM50476062; CCG-50996; ZINC20443805; AKOS008012226; MCULE-1456024115; IDI1_015520; SR-01000640327-1; T5470812
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.66E+13 nM
|
[1] | |||
| Compound Name |
N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219301; N-(2-aminoethyl)-5-chloro-1-naphthalenesulfonamide; Tocris-0366; CBiol_002054; BSPBio_001382; SCHEMBL2739414; CTK3D3017; DTXSID00274345; Bio1_000340; Bio1_000829; Bio1_001318; HMS1791F04; HMS1989F04; HMS3402F04; N-(2-AMINOETHYL)-5-CHLORO-NAPHTHALENE-1-SULFONAMIDE; ZINC2555126; BDBM50375645; SDCCGSBI-0633780.P001; NCGC00024555-01; NCGC00024555-02; NCGC00024555-03; NCGC00024555-04; NCGC00024555-05; NCGC00024555-06; 1-Naphthalenesulfonamide, N-(2-aminoethyl)-5-chloro-; BRD-K51215422-001-02-3; BRD-K51215422-003-01-1; Q27185988; 5-Chloro-naphthalene-1-sulfonic acid, (2-amino-ethyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 5.50E+13 nM
|
[1] | |||
| Compound Name |
[(4-Methylphenyl)sulfonyl](2-{2-[2-(2-{[(4-methylphenyl)sulfonyl]amino}ethoxy) ethoxy]ethoxy}ethyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375083; SCHEMBL9066249; ZINC4256046; BDBM50476060; AKOS001586342; MCULE-9617533838; ST50759389; N,N'-[oxybis(ethane-2,1-diyloxyethane-2,1-diyl)]bis(4-methylbenzenesulfonamide)
Click to Show/Hide
|
||||
| Activity |
IC50 = 4.79E+14 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay. J Med Chem. 2007 Jan 11;50(1):83-93. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.