Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T43206 | Target Info | |||
| Target Name | Nuclear receptor ROR-alpha (RORA) | ||||
| Synonyms |
Retinoid-related orphan receptor-alpha; Retinoic acid-related orphan receptor alpha; RZRA; RAR-related orphan receptor A; Nuclear receptor subfamily 1 group F member 1; Nuclear receptor RZR-alpha; NR1F1
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| Target Type | Preclinical Target | ||||
| Gene Name | RORA | ||||
| Biochemical Class | Nuclear hormone receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-[4-[Hydroxy(dimethyl)silyl]phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3781062; BDBM50152147
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| Activity |
IC50 = 53000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | Altered activity profile of a tertiary silanol analog of multi-targeting nuclear receptor modulator T0901317. Bioorg Med Chem Lett. 2016 Apr 1;26(7):1817-20. | ||||
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