Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T40556 | Target Info | |||
| Target Name | Bromodomain-containing protein 4 (BRD4) | ||||
| Synonyms |
Protein HUNK1; HUNK1
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|
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| Target Type | Clinical trial Target | ||||
| Gene Name | BRD4 | ||||
| Biochemical Class | Bromodomain | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 126 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Vorinostat
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|
Approved | Compound Info | ||
| Synonyms |
NHNPODA; SAHA; SHH; Zolinza; Merck brand of Vorinostat; OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE; SAHA cpd; Suberanilohydroxamic acid; Suberoylanilide hydroxamic acid; Vorinostat MSD; Vorinostat [USAN]; M344; MK0683; SKI390; WIN64652; MK-0683; SAHA, Suberoylanilide hydroxamic acid; SW-064652; Zolinza (TN); Vorinostat (JAN/USAN); N1-hydroxy-N8-phenyloctanediamide; Zolinza, MK-0683, SAHA; N'-hydroxy-N-phenyloctanediamide; N-Hydroxy-N'-phenyl octanediamide; N-Hyrdroxy-N'-phenyloctanediamide; N-hydroxy-N'-phenyloctanediamide; N-hydroxy-N'-phenyl-octane-1,8-diotic acid diamide; Vorinostat (HDAC inhibitor)
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|
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
GSK2801
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|
Investigative | Compound Info | ||
| Synonyms |
KB-146016
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
PFI-4
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|
Investigative | Compound Info | ||
| Synonyms |
900305-37-5; PFI 4; CHEMBL3356143; N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide; N-(1,3-Dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methoxybenzamide; PFI4; GTPL8575; EX-A823; MolPort-004-921-423; BCP23818; ZINC6794685; BDBM50032927; s7906; STL436496; AKOS000482438; CS-4866; MCULE-9591292886; PFI-4, > NCGC00476204-01; HY-18664; FT-0700502; N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
Chembl4207347
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50458954
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Chembl4206870
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL16722302; BDBM50457131
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Chembl4285564
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50465299
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
4-[(E)-2-(2,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-enoyl]-1,3-dihydroquinoxalin-2-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3589481; BDBM50094890
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|
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4293399
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50465298
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
1-{1-[2-(Methylsulfonyl)phenyl]-7-Phenoxyindolizin-3-Yl}ethanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770277; BDBM50148290; Q27461524; IR6
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Chembl4213180
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL16721973; BDBM50457134
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Tert-butyl N-[[3-acetyl-1-(2-methylsulfonylphenyl)indolizin-7-yl]methyl]carbamate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770199; BDBM50148289
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-[7-Methoxy-1-(2-methylsulfonylphenyl)indolizin-3-yl]ethanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770214; BDBM50148334
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Chembl4289367
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50465301
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
1-[1-(2-Methylsulfonylphenyl)indolizin-3-yl]ethanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770847; BDBM50148281
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Chembl4288943
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50465311
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Chembl4290448
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50465303
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
8-{[(5-Amino-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-3-butyl-7-ethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775080; SCHEMBL19066323; BDBM50150714; ZINC12529942; AKOS034740442; MCULE-7211632755; Z96184056; 8-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-3-butyl-7-ethylpurine-2,6-dione
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|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
4-[3-(Benzylamino)-5-methoxybenzoyl]-1,3-dihydroquinoxalin-2-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3589490; BDBM50094919
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|
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4206807
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455503
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[9] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)pyridine-4-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828546; BDBM50189350
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)acetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828426; BDBM50189343
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
3-(2-Oxo-3-methyl-1,2-dihydroquinoline-8-ylamino)propionic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3586695; BDBM50093468
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[10] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperidin-1-ylbenzimidazol-5-yl)-2-methylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1357836; HMS1821F17; ZINC8594568; BDBM50032916; MCULE-2644205696; NCGC00107510-01; C301-5896
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-[1,3-Dimethyl-6-(4-methylpiperazin-1-yl)-2-oxobenzimidazol-5-yl]-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828504; BDBM50189381
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
Chembl4210130
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455495
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[9] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)oxane-4-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827158; BDBM50189346
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)pyrrolidine-3-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828186; BDBM50189345
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
Chembl4204600
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455488
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[9] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828684; BDBM50189409
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)butanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827710; BDBM50189344
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-[1,3-Dimethyl-6-[(3S)-3-methylpiperazin-1-yl]-2-oxobenzimidazol-5-yl]-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828354; BDBM50189405
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperidin-4-ylbenzimidazol-5-yl)-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827434; BDBM50189382
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
3-Methoxy-N-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356147; ZINC9607429; BDBM50032910; MCULE-2447239824
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
Chembl4211914
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455486
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[9] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)pyridine-3-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827941; BDBM50189349
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827629; BDBM50189347
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperazin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827560; BDBM50189357
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
3-Methyl-8-(2-methoxyethylamino)quinoline-2(1H)-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3586694; BDBM50093467
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[10] | |||
| Compound Name |
3-Methyl-8-(propylamino)quinoline-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3586690; BDBM50093463
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[10] | |||
| Compound Name |
N-[1,3-Dimethyl-6-[(2S)-2-methylpiperazin-1-yl]-2-oxobenzimidazol-5-yl]-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828026; BDBM50189404; ZINC653823139
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
Chembl4210762
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455498
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|
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| Activity |
IC50 ~ 50118.72 nM
|
[9] | |||
| Compound Name |
N'-(1,1-Dioxothian-4-yl)-4-oxo-5-propan-2-yl-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770716; BDBM50148455
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[12] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-2-methoxy-benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1702128; MLS001208963; HMS2835F05; ZINC4487941; BDBM50032926; STL119295; AKOS000392437; MCULE-4273441443; SMR000524844; N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-2-methoxybenzamide
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-pyrrolidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-2-phenylacetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356144; BDBM50032923; ZINC20991656; AKOS000482301; MCULE-6276980762
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-[1,3-Dimethyl-6-[(2r)-2-Methylpiperazin-1-Yl]-2-Oxidanylidene-Benzimidazol-5-Yl]-2-Methoxy-Benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
GSK6853; GSK-6853; CHEMBL3828191; GSK 6853; BCP18335; EX-A1080; BDBM50189403; MFCD30489734; s8265; AKOS032944954; ZINC575623806; CCG-268758; CS-5847; BP-25354; BS-16390; GSK6853, >=98% (HPLC); HY-100220; A16330; Q27462469
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
2-Methoxy-N-(1-methyl-2-oxo-6-piperidin-1-yl-3H-benzimidazol-5-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356138; BDBM50032920
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-(1,3-Dimethyl-6-morpholin-4-yl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-3-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1361770; MLS000950489; HMS2943P11; ZINC6794912; BDBM50032909; AKOS000481635; MCULE-9271273220; SMR000622135
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
Chembl4209650
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455485
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[9] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperidin-1-ylbenzimidazol-5-yl)-2,2-dimethylpropanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356141; HMS1624A15; BDBM50032915; CCG-129975; MCULE-2958694388
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-3-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356140; BDBM50032918; ZINC20853236; AKOS000481042; MCULE-4221509383
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1724375; MLS001096186; HMS2943F17; ZINC6915266; BDBM50032917; AKOS000480232; MCULE-3549438228; SMR000630958
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
3-Methyl-8-(1H-imidazole-2-ylmethylamino)quinoline-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3586693; BDBM50093466
Click to Show/Hide
|
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| Activity |
IC50 = 50118.72 nM
|
[10] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-pyrrolidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-3-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1701516; MLS000950529; HMS2937O06; ZINC6794927; BDBM50032922; AKOS000482357; MCULE-9757227560; SMR000622139; J-690386
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
Chembl4246286
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50464132
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[13] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-piperidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-2-phenylacetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356142; BDBM50032914; ZINC20178421; AKOS000481003; MCULE-2004784022
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
N-(1,3-Dimethyl-2-oxo-6-propan-2-yloxybenzimidazol-5-yl)-2,6-dimethoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828299; BDBM50189355
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-[1,3-Dimethyl-2-oxo-6-(1,2,3,6-tetrahydropyridin-4-yl)benzimidazol-5-yl]-2-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828357; BDBM50189386
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
N-(1,3-Dimethyl-6-morpholin-4-yl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-2-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1396002; HMS1821P21; ZINC8594629; BDBM50032924; AKOS000481255; MCULE-4904227087; NCGC00107584-01; C301-6021
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50118.72 nM
|
[11] | |||
| Compound Name |
2-Methoxy-N-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356146; ZINC9607466; BDBM50032925; MCULE-7142170424
Click to Show/Hide
|
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| Activity |
IC50 ~ 50118.72 nM
|
[3] | |||
| Compound Name |
4-(3,5-Diaminophenyl)-3H-1,3-thiazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2349345; BDBM50432489
Click to Show/Hide
|
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| Activity |
IC50 = 50700 nM
|
[14] | |||
| Compound Name |
Chembl4160166
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50406030
Click to Show/Hide
|
||||
| Activity |
IC50 = 50750 nM
|
[15] | |||
| Compound Name |
N-(2,5-Dimethylphenyl)-3,3-diphenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4068849; Oprea1_492579; ZINC995007; BDBM50238044; STK416597; AKOS001078650; MCULE-7432501839; ST45144119; AK-968/11842299
Click to Show/Hide
|
||||
| Activity |
IC50 = 50750 nM
|
[16] | |||
| Compound Name |
N-{4-[Acetyl(methyl)amino]phenyl}-2-(4-bromo-2-chlorophenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4071717; ARONIS004303; KS-00003X3Q; ZINC6304119; BDBM50238035; STK064311; AKOS000493933; MCULE-2939001972; AN-329/41675140; N-(4-{[(4-bromo-2-chlorophenoxy)acetyl]amino}phenyl)-N-methylacetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 50920 nM
|
[16] | |||
| Compound Name |
4-(4-Aminophenyl)-3H-1,3-thiazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2349343; SCHEMBL11491535; BDBM50432491; AKOS017518295
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[14] | |||
| Compound Name |
3-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-5-Ethoxybenzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1828984; BDBM50353594; Q27462090; KRG
Click to Show/Hide
|
||||
| Activity |
IC50 = 51200 nM
|
[17] | |||
| Compound Name |
N-Tert-butyl-2-[6-(3,5-dimethyl-1,2-oxazol-4-yl)pyridin-3-yl]imidazo[1,2-a]pyrazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356566; SCHEMBL16424672; BDBM50030899
Click to Show/Hide
|
||||
| Activity |
IC50 = 51900 nM
|
[18] | |||
| Compound Name |
6-Acetyl-3-(3-chlorophenyl)-1-(cyclopropylmethyl)-7,8-dihydro-5H-1,6-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4077375; BDBM50250887
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[19] | |||
| Compound Name |
4-Methyl-1,3,4,5-tetrahydro-1-benzazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3814217; ACMC-20le6h; 2H-1-Benzazepin-2-one, 1,3,4,5-tetrahydro-4-methyl-, (R)-; SCHEMBL1347231; BDBM50178195; 2H-1-Benzazepin-2-one, 1,3,4,5-tetrahydro-4-methyl-
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[20] | |||
| Compound Name |
1-(3-Phenylazanyl-1,4,6,7-Tetrahydropyrazolo[4,3-C]pyridin-5-Yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3959584; SCHEMBL17794885; BDBM50200385; J3.616.625H; N-Phenyl-5-acetyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-amine; 1-(3-(PHENYLAMINO)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL)ETHAN-1-ONE
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[21] | |||
| Compound Name |
Chembl4127306
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50273495; ZINC69568297; AKOS034728189; MCULE-1971809011; Z955345716; 3-(2,5-dimethoxyphenyl)-N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)propanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[22] | |||
| Compound Name |
5-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-1,3,6-trimethylpyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3824351; SCHEMBL19869785; BDBM50183452
Click to Show/Hide
|
||||
| Activity |
IC50 = 61917 nM
|
[23] | |||
| Compound Name |
COc1cccc(c1)C(=O)Nc2ncnc3[nH]cnc23
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3398334; BDBM50103492
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[24] | |||
| Compound Name |
6-(3,5-Dimethyl-1,2-oxazol-4-yl)-2,3-dihydroinden-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3220851; BDBM50496795
Click to Show/Hide
|
||||
| Activity |
IC50 = 63095.73 nM
|
[25] | |||
| Compound Name |
3,5 Dimethyl-4-Phenyl-1,2-Oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,5-dimethyl-4-phenyl-1,2-oxazole; CHEMBL1828979; 4-Phenyl 3,5-Dimethyl Isoxazole; Isoxazole, 3,5-dimethyl-4-phenyl-; 3,5-Dimethyl-4-phenylisoxazole; SCHEMBL12134072; DTXSID00416046; BDBM50353589; ZINC33836256; AKOS015951136; Q27457171; Z1939437573
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[18] | |||
| Compound Name |
7-N,5-Dimethyl-7-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-2,7-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2436006; BDBM50441762; N',5-Dimethyl-N'-(4-methylbenzyl)[1,2,4]triazolo[1,5-a]pyrimidine-2,7-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[26] | |||
| Compound Name |
5-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-1,3,4-trimethylpyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823551; SCHEMBL19869776; BDBM50183451
Click to Show/Hide
|
||||
| Activity |
IC50 = 67479 nM
|
[23] | |||
| Compound Name |
Chembl4172354
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50406022
Click to Show/Hide
|
||||
| Activity |
IC50 = 69230 nM
|
[15] | |||
| Compound Name |
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-5-methyl-2-phenyl-1,3-dioxane-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1698814; MLS000729342; HMS2719G04; ZINC1431459; BDBM50238034; STK267351; AKOS003395071; SMR000307620; AO-080/42330320
Click to Show/Hide
|
||||
| Activity |
IC50 = 69230 nM
|
[16] | |||
| Compound Name |
4-[4-[6-(4-Methoxyphenyl)-2-phenylpyrimidin-4-yl]phenyl]-3,5-dimethyl-1,2-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356542; BDBM50030925
Click to Show/Hide
|
||||
| Activity |
IC50 = 69900 nM
|
[18] | |||
| Compound Name |
4-Acetyl-2-methylisoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1443641; 4-Acetyl-2-methyl-2H-isoquinolin-1-one; MLS001049353; SCHEMBL13209949; HMS2784I14; ZINC440341; BDBM50461598; STK835346; AKOS001582523; MCULE-4016073560; 4-acetyl-2-methylisoquinolin-1(2H)-one; SMR000427339; SR-01000388356; SR-01000388356-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 71000 nM
|
[27] | |||
| Compound Name |
Chembl4226129
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50461601
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[27] | |||
| Compound Name |
1-Methyl-2-quinolone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-METHYL-2-QUINOLINONE; 1-METHYLQUINOLIN-2(1H)-ONE; N-Methylcarbostyril; 1-methylquinolin-2-one; 1-Methyl-2(1H)-quinolinone; 2(1H)-Quinolinone, 1-methyl-; 1-Methylcarbostyril; Carbostyril, 1-methyl-; 1-Methyl-2(1H)-quinolone; 1-methyl-1,2-dihydroquinolin-2-one; UNII-UQ470VV48X; 2(1H)-Quinolinone, methyl-; MLS002637847; CHEMBL216146; UQ470VV48X; MFCD00024051; 1-methylhydroquinolin-2-one; NSC 5873; N-methyl-2-quinolone; PubChem15912; AI3-24119; 1-methyl-quinolin-2-one; N-Methyl-quinolin-2-one; C3b N-Methyl-2-quinolone; 2-Hydroxy-1-methylquinoline; ACMC-1BH74; 1-methyl-1H-quinolin-2-one; SCHEMBL248619; DTXSID1060552; Carbostyril, 1-methyl- (8CI); CTK2I8695; QYEMNJMSULGQRD-UHFFFAOYSA-; NSC5873; HMS3604D09; ZINC336851; ALBB-032305; NSC-5873; BBL019043; BDBM50157646; SBB087359; STK736383; AKOS000276919; CS-W023164; DB04580; HR-0330; MCULE-8485036701; SMR001547359; DB-053678; ST4129070; FT-0632523; H2834; 606M439; A832822; AO-840/40233519; Q27095322; F3308-4039
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[28] | |||
| Compound Name |
CID 90388523
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3581652; SCHEMBL16010461; BDBM50092327; 4-(1-chloro-8-methoxy-5H-pyrido[4,3-b]indol-7-yl)-3,5-diethyl-1,2-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 73970 nM
|
[29] | |||
| Compound Name |
4-Fluoro-2-methyl-N-(1-propionyl-1,2,3,4-tetrahydroquinolin-6-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4097164; BDBM50250894; ZINC17248182; AKOS004993610; MCULE-1086892379; F2041-0379
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[19] | |||
| Compound Name |
5-Methyl-7-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-2,7-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2436007; BDBM50441761
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[26] | |||
| Compound Name |
3-Chloro-5-[2-(2,3-dihydro-1,4-benzodioxin-5-yl)-5-(2-methylpropyl)-1,2,4-triazol-3-yl]-1H-pyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2436003; BDBM50441764
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[26] | |||
| Compound Name |
2,3-Dimethoxy-N-(7H-purin-6-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3398330; BDBM50103494
Click to Show/Hide
|
||||
| Activity |
IC50 = 78600 nM
|
[24] | |||
| Compound Name |
4-[[(1S,3R)-3-Benzyl-6-(3,5-dimethyl-1,2-oxazol-4-yl)-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-1-yl]methyl]morpholine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4103824; BDBM50238141
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[30] | |||
| Compound Name |
2-Methyl-3,5-dihydro-2H-1,5-benzoxazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2282031; CTK7H2473; HMS1664N06; BDBM50178199; CCG-41880; MCULE-6071554607; 2,3-dihydro-2-methyl-1,5-benzoxazepin-4(5h)-one; SR-01000631926-1; 2-methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one; 2-Methyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one #; 6-Methyl-6,7-dihydro-9H-5-oxa-9-azabenzocyclohepten-8-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[20] | |||
| Compound Name |
3-Methyl-4-[3-(trifluoromethyl)phenyl]-5-isoxazolamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2436014; 3-methyl-4-[3-(trifluoromethyl)phenyl]-1,2-oxazol-5-amine; CTK6C4979; KS-00001RBH; ZINC3883285; BDBM50441765; MFCD03791146; SBB099552; AKOS005069279; MCULE-2005169448; 10T-0381; 3-Methyl-4-(3-(trifluoromethyl)phenyl)isoxazol-5-amine; 3-Methyl-4-[3-(trifluoromethyl)phenyl]isoxazole-5-amine; 3-methyl-4-[3-(trifluoromethyl)phenyl]isoxazole-5-ylamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 80900 nM
|
[26] | |||
| Compound Name |
Chembl4228900
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50461604
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[27] | |||
| Compound Name |
5-[4-[(Dimethylamino)methyl]-3-methoxyphenyl]-1,3-dimethylpyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822988; SCHEMBL19869840; BDBM50183572
Click to Show/Hide
|
||||
| Activity |
IC50 = 81300 nM
|
[23] | |||
| Compound Name |
N-Methyl-7-pyrrolidin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3448459; BDBM50250893
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 84000 nM
|
[19] | |||
| Compound Name |
4-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methylisoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3824133; SCHEMBL19869876; BDBM50183450
Click to Show/Hide
|
||||
| Activity |
IC50 = 86973 nM
|
[23] | |||
| Compound Name |
Chembl4226431
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50461596; 2-Ethyl-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[27] | |||
| Compound Name |
8-[4-[(Dimethylamino)methyl]-3,5-dimethoxyphenyl]-6-methylpyrido[4,3-d]pyrimidin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3824312; SCHEMBL19869879; BDBM50183453
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-[4-[(Dimethylamino)methyl]-3,5-Dimethoxy-Phenyl]-2-Methyl-2,7-Naphthyridin-1-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BI-7273; CHEMBL3823478; BI7273; GTPL9146; SCHEMBL19869878; EX-A990; BCP17545; BDBM50183448; MFCD30489736; s8179; ZINC575448880; CCG-268068; CS-5887; HY-100351; J3.533.936A; A16068; Q27075221
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4059509; BDBM50249797
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
3-Methyl-6-amino-2(3H)-benzothiazolone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-Amino-3-methylbenzo[d]thiazol-2(3H)-one; 6-AMINO-3-METHYL-2,3-DIHYDRO-1,3-BENZOTHIAZOL-2-ONE; CHEMBL4072960; 6-amino-3-methyl-1,3-benzothiazol-2(3H)-one; Oprea1_024205; SCHEMBL3035789; BDBM50250886; MFCD00848405; STL507403; AKOS037489236; 6-amino-3-methyl-2(3H)-benzothiazolone; AS-68875; 6-amino-3-methyl-1,3-benzothiazol-2-one; DB-100479; CS-0060742
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
Chembl4127934
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ZINC4539465; BDBM50273484; AKOS001358705; MCULE-2195630011; UPCMLD0ENAT5851246:001; ST50165757; Z111781466; 5-chloro-1-(3-phenoxypropyl)benzo[d]azolidine-2,3-dione; 5-chloro-1-(3-phenoxypropyl)-2,3-dihydro-1H-indole-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
Chembl4126540
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50270480; AKOS001373205; AKOS016846412; MCULE-9131531526
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
(3R)-1-[4-(3,5-Dimethyl-1,2-oxazol-4-yl)phenyl]-2,5-diethyl-3-methyl-4,6-dioxo-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356136; BDBM50030928
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
Chembl4128551
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50273479; ZINC10577092; AKOS033836463; MCULE-3188113450; AB00783370-01; Z226429830; 4-methyl-3-nitro-N-[2-(pyrrolidin-1-yl)-1,3-benzothiazol-6-yl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
Cc1noc(C)c1-c1ccc(cc1)-c1nc2cnccn2c1NCC(O)=O
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356553; SCHEMBL16415660; BDBM50030914; 2-((2-(4-(3,5-Dimethylisoxazol-4-yl)phenyl)imidazo[1,2-a]pyrazin-3-yl)amino)acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(2R)-N,2,7-Trimethyl-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4089325; BDBM50269854; ZINC75403643; 9UG
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
Methyl indole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Methyl 1H-indole-3-carboxylate; Indole-3-carboxylic Acid Methyl Ester; Methyl 3-indolecarboxylate; 1H-Indole-3-carboxylic acid, methyl ester; 3-carbomethoxyindole; 3-methoxycarbonylindole; 1H-Indole-3-carboxylic acid methyl ester; methylindole-3-carboxylate; MFCD00189407; Indole-3-carboxylic acid, methyl ester; CHEMBL2270066; 3-carbomethoxy indole; PubChem7506; ACMC-209rqq; methyl indole 3-carboxylate; 3-methoxycarbonyl-1H-indole; KSC490C1F; SCHEMBL1093530; CTK3J0112; KS-00000BOI; ZINC66126; DTXSID10343334; HMS1661G01; Methyl 1H-indole-3-carboxylate #; Methyl indole-3-carboxylate, 99%; BCP00917; CS-D1229; ANW-40224; BBL010669; BDBM50250885; HTS001783; METHYL INDOLE-3- CARBOXYLATE; SBB012373; STK397421; AKOS000579454; MCULE-1094551134; SDCCGMLS-0065824.P001; AK-47146; SC-46735; SC-63798; ST066881; SY020043; AB0021789; FT-0628332; I0491; W1078; I-2505; M-5770; 7T-1502; Q27133581; Z57164966; F2190-0648
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
Ethyl N-[(4S)-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2430872; BDBM50441169
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[33] | |||
| Compound Name |
Cc1noc(C)c1-c1ccc(cc1)-c1nc2ccc(C)cn2c1NCc1ccccc1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356544; SCHEMBL16416647; BDBM50030923
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
2-(3,5-Dimethyl-1,2-oxazol-4-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356130; SCHEMBL2498903; BDBM50030934
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
4-[4-[(Dimethylamino)methyl]-2,5-Dimethoxy-Phenyl]-2-Methyl-2,7-Naphthyridin-1-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BI-9564; BI 9564; CHEMBL3823101; GTPL8950; SCHEMBL19869872; BCP17135; EX-A1652; BDBM50183449; BI9564; s8113; AKOS027470219; ZINC526061652; CCG-268067; CS-5888; AK685542; BP-25349; BS-15735; DS-001715; HY-100352; BI-9564, >=97% (HPLC); J3.600.898I; Q27075224
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-(2-Fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(2-Fluorophenyl)-1,3-Thiazol-2(3h)-One; CHEMBL3409981; CTK7C2368; BDBM50071108; ZINC34669942; AKOS008126821; MCULE-8344648568; NE27020; EN300-59193; Q27451843; Z1222423420
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
5-[4-[(Dimethylamino)methyl]-3,5-dimethoxyphenyl]-7-methyl-1,7-naphthyridin-8-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822909; SCHEMBL19857609; BDBM50183560
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-[4-[(Dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-2,6-naphthyridin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823859; SCHEMBL19869894; BDBM50183517
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
Methyl 2-[[2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl]amino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PRMT5-IN-C17; ZINC00659298; ChemDiv1_002844; Oprea1_645106; CHEMBL4092336; HMS595B06; ZINC5455374; STK346078; AKOS000421473; AKOS000830714; MCULE-9755352312; AG-690/12869587; SR-01000429953; SR-01000429953-1; Z16078172; methyl 2-({[(5-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl}amino)benzoate; methyl 2-({[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl}amino)benzoate; methyl 2-{2-[(6-methoxy-1H-1,3-benzodiazol-2-yl)sulfanyl]acetamido}benzoate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
8-[4-[(Dimethylamino)methyl]-3,5-dimethoxyphenyl]-6-methyl-1,6-naphthyridin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822539; SCHEMBL19869895; BDBM50183454
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
5-{4-[(Dimethylamino)methyl]-3,5-dimethoxyphenyl}-1,3,6-trimethyl-1,2-dihydro-pyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823697; BI-7189; SCHEMBL19869680; BDBM50183563; J3.533.937J
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-[(4-Hydroxy-3,5-dimethylphenyl)diazenyl]-N-[[4-(trifluoromethyl)phenyl]methyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087053; BDBM50443261
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[36] | |||
| Compound Name |
4-[2-[5-(3,5-Dimethyl-1,2,4-triazol-1-yl)-2-(2-phenylethyl)benzimidazol-1-yl]ethyl]morpholine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4095836; BDBM50238144
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[30] | |||
| Compound Name |
4-[2-[5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-[2-(4-methoxyphenyl)ethyl]indol-1-yl]ethyl]morpholine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4076179; BDBM50238147
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[30] | |||
| Compound Name |
5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-[2-(4-methoxyphenyl)ethyl]-1-(2-morpholin-4-ylethyl)indole-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4078551; BDBM50238148
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[30] | |||
| Compound Name |
Isox inact
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
ISOX-INACT; CHEMBL4079322; BDBM188518; AKOS027470296; ZINC526061585; ISOX-INACT, >=98% (HPLC); NCGC00483116-01
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[37] | |||
| Compound Name |
Chembl4225778
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50461600
Click to Show/Hide
|
||||
| Activity |
IC50 = 121000 nM
|
[27] | |||
| Compound Name |
1-Acetyl-2-methyl-1,2,3,4-tetrahydroquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1950955; MS2126; 1-Acetyl-1,2,3,4-tetrahydro-quinaldine; 1-(2-methyl-3,4-dihydroquinolin-1(2H)-yl)ethanone; Ethanone,1-(3,4-dihydro-2-methyl-1(2H)-quinolinyl)-; 1-(2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone; NSC71584; Cambridge id 5102126; NCIOpen2_000381; SCHEMBL1825815; CTK4D0574; DTXSID30290876; BDBM50455513; NSC-71584; STK251711; AKOS001611921; AKOS016038548; CCG-104489; MCULE-2219050180; DB-126513; ST45021969; AB00073600-01; 1-(3,4-dihydro-2-methyl-1(2H)-quinolinyl)Ethanone; Z28870646; 1-(2-methyl-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one; 1-(2-Methyl-3,4-dihydroquinolin-1(2H)-yl)ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 125892.54 nM
|
[9] | |||
| Compound Name |
Chembl4250812
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50464127
Click to Show/Hide
|
||||
| Activity |
IC50 = 158489.32 nM
|
[13] | |||
| Compound Name |
8-[[3-(Dimethylamino)-2,2-dimethylpropyl]amino]-3-methyl-1H-1,7-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3586708; BDBM50093455
Click to Show/Hide
|
||||
| Activity |
IC50 = 158489.32 nM
|
[10] | |||
| Compound Name |
2-Methyl-5-(Methylamino)-6-Phenylpyridazin-3(2h)-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4068525; Oprea1_854962; BDBM50265654; 89J
Click to Show/Hide
|
||||
| Activity |
Ki = 160000 nM
|
[38] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 15 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Dimethyl Sulfoxide
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Rimso-50
Click to Show/Hide
|
||||
| Activity |
IC50 = 280000000 nM
|
[39] | |||
| Compound Name |
Chembl4291774
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50468499; AKOS033248097; MCULE-9813193267; Z1313379445; N-{4-[(3,5-dimethylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}-2,4-dimethyl-1,3-oxazole-5-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[40] | |||
| Compound Name |
(2S)-2-(Hydroxymethyl)-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3815068; SCHEMBL4905898; BDBM50178201
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
3-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Methyl-1,3,4,5-tetrahydro-benzo[b][1,4]diazepin-2-one; CHEMBL3813890; 2,3-Dihydro-3-methyl-1,5-benzodiazepin-4(5H)-one; F1216-0227; 3-methyl-2,3,4,5-tetrahydro-1,5-benzodiazepin-2(1H)-one; 3-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one; Oprea1_309360; SCHEMBL11658348; CTK6C3642; KS-00003KIT; 3-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one; DTXSID90389992; HMS1683H19; ALBB-017638; 5239AE; BDBM50178205; MFCD00168266; SBB027802; STK866162; AKOS000275345; AKOS016040985; FS-1830; MCULE-7989418370; AB0159584; BB 0219740; FT-0687545; ST50070595; EN300-48621; L-4371; 3-methyl-1H,3H,4H,5H-benzo[b]1,4-diazepin-2-one; 2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-3-methyl-; 3-methyl-1H,3H,4H,5H-benzo[b]1,4-diazaperhydroepin-2-one; 3-Methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
1,3,4,5-Tetrahydro-2H-1,5-benzodiazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one; 1,3,4,5-Tetrahydro-benzo[b][1,4]diazepin-2-one; 1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one; 2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one; NSC 11707; 2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-; 1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one; CHEMBL3814945; MFCD00612448; 1,3,4,5-Tetrahydrobenzo[b][1,4]diazepin-2-one; NSC11707; Oprea1_427458; Oprea1_532708; SCHEMBL4071447; CTK1H2663; KS-00001ZZQ; DTXSID20279211; ALBB-017852; CS-B1191; ZINC3865934; ANW-64213; BDBM50178206; NSC-11707; SBB045898; STK866161; AKOS000271473; MCULE-9582091420; SDCCGMLS-0065551.P001; AK-45215; AM806818; BR-45215; DA-19095; SY079183; DB-027128; BB 0216543; FT-0657643; ST50070594; W7095; 1H,3H,4H,5H-benzo[b]1,4-diazepin-2-one; EN300-79181; 55T077; S-6034; 4,5-Dihydro-1H-1,5-benzodiazepin-2(3H)-one; 7W-0803; A831499; 1,3,4,5-tetrahydro-1,5-benzodiazepin-2(2H)-one; 1,3,4,5-tetrahydro-2H-1,5-benzodiazepine-2-One; 1,3,4,5-Tetrahydrobenzo[b] [1,4]diazepin-2-one; 1H,3H,4H,5H-benzo[b]1,4-diazaperhydroepin-2-one; 2-Oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine; J-514090; 2,6-diazabicyclo[5.4.0]undeca-7,9,11-trien-5-one; F1216-0226
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
Chembl4228106
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BDBM50461603
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[27] | |||
| Compound Name |
(2R)-2-Ethyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3813701; SCHEMBL17680224; BDBM50178202
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
4,4-Dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3813958; SCHEMBL4910229; 4,4-dimethyl-1,3,4,5-tetrahydro-benzo[b][1,4]diazepin-2-one; BDBM50178203; MFCD21840720; ZINC38887912; AKOS017844130; NE20135; 4,4-dimethyl-3,5-dihydro-1H-1,5-benzodiazepin-2-one; 4,4-dimethyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one; 4,4-dimethyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2(2H)-one; 4,4-dimethyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
4-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC 36330; 4-Methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one; 4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one; 2-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one; MLS002607962; CPI098; CHEMBL2142704; NSC36330; 4-Methyl-1,3,4,5-tetrahydro-benzo[b][1,4]diazepin-2-one; 4-Methyl-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one; F0266-2229; 4-methyl-1H,3H,4H,5H-benzo[b]1,4-diazaperhydroepin-2-one; BRN 0166063; Maybridge1_000473; Oprea1_799819; SCHEMBL4902318; CTK4I1713; HMS542N11; HMS3080B19; ALBB-017639; 1H-1,5-BENZODIAZEPIN-2-ONE, 2,3,4,5-TETRAHYDRO-4-METHYL-; BDBM50178217; MFCD00024148; NSC-36330; SBB039215; STK866163; AKOS000272070; AKOS016039074; MCULE-3074358862; MS-2384; KS-0000284A; SMR001335214; DB-049463; BB 0219744; FT-0635078; ST50112412; Y8991; EN300-09458; L-4033; 5-24-02-00516 (Beilstein Handbook Reference); AE-473/30685015; SR-01000394501; J-515749; SR-01000394501-1; W-204277; 2,3,4,5-Tetrahydro-4-methyl-1H-1,5-benzodiazepin-2-one; 4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2one; 2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-4-methyl-; 2H-1,5-Benzodiazepin-2-one,1,3,4,5-tetrahydro-4-methyl-
Click to Show/Hide
|
||||
| Activity |
IC50 = 220000 nM
|
[20] | |||
| Compound Name |
(4r)-4-Methyl-1,3,4,5-tetrahydro-2h-1,5-benzodiazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3814920; SCHEMBL17680584; CTK8E0429; ZINC152521; BDBM50178216; Q27456974; (4R)-1,3,4,5-Tetrahydro-4-methyl-2H-1,5-benzodiazepine-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 260000 nM
|
[20] | |||
| Compound Name |
3-Methyl-8-(2-dimethylaminoethylamino)pyrido[3,4-b]pyridine-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3586696; BDBM50093469
Click to Show/Hide
|
||||
| Activity |
IC50 > 501187.23 nM
|
[10] | |||
| Compound Name |
(4s)-4-Methyl-1,3,4,5-tetrahydro-2h-1,5-benzodiazepin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3814706; SCHEMBL17680234; CTK8E0436; ZINC152520; BDBM50178208; TS-02442; 4alpha-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Click to Show/Hide
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||||
| Activity |
IC50 = 3700000 nM
|
[20] | |||
| Compound Name |
1-Methyl-2-pyrrolidinone
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|
Investigative | Compound Info | ||
| Synonyms |
N-Methylpyrrolidone; N-Methyl-2-pyrrolidone; 1-methylpyrrolidin-2-one; Methylpyrrolidone; 1-Methyl-2-pyrrolidone; N-Methyl-2-pyrrolidinone; M-Pyrol; N-Methylpyrrolidinone; 1-Methylpyrrolidone; 2-Pyrrolidinone, 1-methyl-; 1-Methylpyrrolidinone; n-methyl-pyrrolidone; 1-Methylazacyclopentan-2-one; 1-Methyl-5-pyrrolidinone; N-methylpyrrolidin-2-one; N-Methyl-gamma-butyrolactam; N-methyl pyrrolidone; 1-methylpyrrolidine-2-one; N-methyl pyrrolidinone; Methyl-2-pyrrolidinone; 1-methyl-2-pyrrolidon; Methyl pyrrolidone; Methylpyrrolidinone; UNII-JR9CE63FPM; N-Methyl-alpha-pyrrolidone; N-Methylpyrrolidon; NSC 4594; Agsolex 1; N-Methyl-alpha-pyrrolidinone; N-methyl-pyrrolidinone; N-Methyl-2-pyrrolidon; N-Methylpyrrolid-2-one; MFCD00003193; JR9CE63FPM; N-methyl-pyrrolidin-2-one; 1-methyl-pyrrolidin-2-one; N-Methyl-.alpha.-pyrrolidone; CHEMBL12543; N-Methyl-.gamma.-butyrolactam; N-Methyl-.alpha.-pyrrolidinone; DTXSID6020856; NSC-4594; N-Methylpyrrolidinon; 1-Methyl-2-pyrrolidinone, anhydrous; 1-Methyl-2-pyrrolidinone, HPLC Grade; DSSTox_CID_856; N 0131; DSSTox_RID_75828; DSSTox_GSID_20856; pharmasolve; 2-Pyrrolidinone, methyl-; CCRIS 1633; Methylpyrrolidone, N-; HSDB 5022; Pyrrolidinone, methyl-; 1-Methyl-2-pyrrolidinone, 99.5%, for HPLC; Methylpyrrolidone [NF]; 1-Methyl-2-pyrrolidinone, 99.5+%, ACS reagent; 1-Methyl-2-pyrrolidinone, 99+%, for spectroscopy; EINECS 212-828-1; Micropure ultra; AI3-23116; N-methypyrrolidone; Pyrol M; N-methylpirrolidone; 1methylpyrrolidinone; n-methyl pyrrolidon; n-methylbutyrolactam; N-methy pyrrolidone; N-methyl-pyrolidone; N-methyl-pyrrolidon; N-methylpyrolidinone; 1-methylpyrolidinone; Microposit 2001; n-methylpyrollidinone; N-methlypyrrolidinone; N-methyl pirrolidone; N-methyl pyrollidone; N-methyl-pyrollidone; N-methylpyrrolidone-; NMP,SP Grade; 1-methyl pyrrolidone; 1-methyl-pyrrolidone; methyl-2-pyrrolidone; N-methy pyrrolidinone; N-methyl pyrolidinone; N-methyl-pyrolidinone; N-methyl- pyrrolidone; N-methylpyrro-lidinone; N-methylpyrroli-dinone; N-methylpyrrolidin-one; 1-methyl-2pyrrolidone; 1-methyl2-pyrrolidone; 1methyl-2-pyrrolidone; 1-methyl pyrrolidinone; 1-methyl-pyrrolidinone; methylpyrrolidin-2-one; N-methy-2-pyrrolidone; N-methyl 2-pyrolidone; N-methyl-2-pyrolidone; 1-methyl-2-pyrolidone; PubChem17618; N-methyl 2-pyrrolidone; N-methyl-2-pyrollidone; 1-methyl-2-pirrolidone; 1-methyl-2-pyroldinone; 1-methylpyrrolid-2-one; 1methyl-2-pyrrolidinone; ACMC-1CKWA; n-methylpyrrolidine-2one; N-methyl-2-pyrolidinone; N-methyl-2-pyrrolidinon; N-methylpyrolidin-2-one; 1-methy-2-pyrrolidinone; 1-methyl-2-pyrolidinone; N-methyl 2-pyrrolidinone; N-methyl-2-pyrollidinone; N-methyl-pyrrolid-2-one; N-methylpyrollidin-2-one; 1 -methyl-2-pyrrolidone; 1-methyl 2-pyrrolidinone; 1-methyl-2-pyrollidinone; 1-methyl-pyrrolin-2-one; N-Methylpyrrolidone-(2); NMP, N-Methylpyrrolidone; 1-Methyl-pyrrolidin-2one; N-methylpyrrolidine-2-one; WLN: T5NVTJ A; N-methyl -2-pyrrolidinone; 1 -methyl-2-pyrrolidinone; 1-methyl -2-pyrrolidinone; 1-methyl-2- pyrrolidinone; EC 212-828-1; 2-Pyrrolidone, 1-methyl-; 1-methyl-pyrrolidine-2-one; 1-N-methyl-2-pyrrolidinone; N-methyl-pyrrolidin -2-one; KSC201Q7R; 1-Methylazacyclopentane-2-one; GTPL9520; 1-Methyl-2- pyrrolidin-2-one; CTK1A1878; NSC4594; KS-000002OB; ZINC3860621; Tox21_202350; Tox21_300097; 1-Methyl-2-pyrrolidinone, 99.5%; 2447AB; ANW-38658; BDBM50353587; N-Methyl pyrrolidon (Peptide Grade); s6282; SBB060297; STL183295; N-Methyl-2-pyrrolidinone ACS reagent; AKOS000120930; 1-Methyl-2-pyrrolidinone, BioSolv(R); DB12521; MCULE-1381506705; SL 1332; 1-Methyl-2-pyrrolidone, Reagent, ACS; NCGC00247902-01; NCGC00247902-02; NCGC00253935-01; NCGC00259899-01; BR-30156; SC-18144; 1-Methyl-2-pyrrolidinone, 99%, extra pure; 1-Methyl-2-pyrrolidone (Low water content); AM20110252; CS-0017258; FT-0608052; FT-0672137; FT-0698122; FT-0700571; M0418; M3055; ST51046511; 1-Methyl-2-pyrrolidinone, analytical standard; 1-Methyl-2-pyrrolidinone, anhydrous, 99.5%; 1-Methyl-2-pyrrolidinone, for HPLC, >=99%; 1-Methyl-2-pyrrolidinone, for synthesis, 99%; C11118; M 0418; Q33103; Residual Solvent Class 2 - N-Methylpyrrolidone; 1-Methyl-2-pyrrolidinone, ReagentPlus(R), 99%; 17283-EP2272834A1; 17283-EP2272849A1; 17283-EP2275469A1; 17283-EP2287153A1; 17283-EP2287940A1; 17283-EP2289510A1; 17283-EP2289868A1; 17283-EP2289965A1; 17283-EP2295399A2; 17283-EP2298313A1; 17283-EP2298763A1; 17283-EP2298767A1; 17283-EP2298828A1; 17283-EP2301929A1; 17283-EP2301935A1; 17283-EP2301983A1; 17283-EP2305243A1; 17283-EP2305674A1; 17283-EP2308838A1; 17283-EP2308857A1; 17283-EP2308926A1; 17283-EP2309564A1; 17283-EP2309584A1; 17283-EP2311815A1; 17283-EP2311831A1; 17283-EP2314586A1; 17283-EP2314587A1; 32226-EP2301933A1; 32226-EP2311827A1; 32356-EP2298731A1; 32356-EP2301933A1; 32356-EP2311827A1; 33443-EP2287147A2; 33443-EP2292624A1; 33443-EP2295409A1; 33443-EP2301922A1; 33443-EP2308812A2; 33443-EP2311815A1; 34253-EP2269989A1; 34253-EP2270113A1; 34253-EP2272817A1; 34253-EP2272935A1; 34253-EP2277875A2; 34253-EP2292607A2; 34253-EP2298778A1; 34253-EP2305657A2; 34253-EP2308492A1; 34253-EP2311850A1; 47604-EP2269983A1; 47604-EP2269984A1; 47604-EP2269990A1; 47604-EP2277875A2; 47604-EP2292227A2; 47604-EP2298770A1; 47604-EP2298774A1; 47604-EP2301921A1; 47604-EP2301926A1; 47604-EP2305642A2; 47604-EP2305650A1; 47604-EP2305667A2; 47604-EP2308861A1; 47604-EP2308880A1; 47604-EP2311811A1; 49793-EP2272509A1; 49793-EP2272835A1; 49793-EP2272848A1; 49793-EP2274983A1; 49793-EP2277858A1; 49793-EP2283898A1; 49793-EP2292607A2; 49793-EP2295411A1; 49793-EP2298761A1; 49793-EP2305633A1; 49793-EP2305687A1; 49793-EP2308812A2; 49793-EP2308960A1; 49793-EP2311824A1; 49793-EP2311825A1; 49793-EP2380872A1; 72367-EP2279741A2; 72367-EP2287153A1; 72367-EP2287155A1; 72367-EP2292615A1; 72367-EP2295415A1; 72367-EP2298747A1; 72367-EP2308867A2; 72367-EP2308870A2; 77850-EP2272846A1; 77850-EP2277868A1; 77850-EP2277869A1; 77850-EP2277870A1; 77850-EP2284166A1; 77850-EP2292608A1; 77850-EP2292616A1; 77850-EP2298305A1; 77850-EP2298749A1; 77850-EP2305033A1; 77850-EP2308866A1; 78692-EP2277875A2; 78692-EP2292619A1; 78692-EP2305667A2; 78692-EP2305688A1; 78692-EP2375479A1; 85636-EP2292616A1; 85636-EP2298769A1; 85636-EP2305657A2; 107610-EP2272517A1; 107610-EP2298746A1; 108900-EP2281861A2; 108900-EP2298769A1; 139735-EP2269983A1; 139735-EP2269984A1; 139735-EP2292607A2; 153002-EP2280002A1; 153002-EP2287164A1; 153002-EP2289881A1; 2-PYRROLIDONE,1-METHYL MFC5 H9 N1 O1; A842053; 1-Methyl-2-pyrrolidinone, ACS reagent, >=99.0%; 2,5-Dichloro-4,6-dimethyl pyridine-3-carbonitrile; J-504921; J-803017; 1-Methyl-2-pyrrolidinone, biotech. grade, >=99.7%; 1-Methyl-2-pyrrolidinone, p.a., ACS reagent, 99%; F0001-2169
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| Activity |
IC50 = 6000000 nM
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[39] | |||
| Compound Name |
(2S)-6-Acetamido-N-methyl-2-(methylamino)hexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134571; SCHEMBL18117452
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| Activity |
IC50 = 7000000 nM
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[39] | |||
| Compound Name |
(R)-(-)-JQ1 Enantiomer
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Investigative | Compound Info | ||
| Synonyms |
(-)-JQ1; (-)-JQ-1; (R)-JQ1; LSM-6333; SCHEMBL881208; CHEMBL3220211; EX-A463; BDBM205429; 2826AH; HY-13030A; MFCD22124456; ZINC71789385; AKOS025147026; CS-0646; DS-8567; SB17022; (R)-(-)-JQ1; (R)-JQ1 (3); (?)-JQ-1; A8181; SW220194-1; (-)-JQ1, >=95% (HPLC); A14160; W-5859; Q27166849
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| Activity |
IC50 = 8354000 nM
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[41] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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