Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T40192 | Target Info | |||
| Target Name | DNA-binding factor KBF1 (p105) | ||||
| Synonyms |
Nuclear factor of kappa light polypeptide gene enhancer in Bcells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor NFkappaB p50 subunit; Nuclear factor NFkappaB p105 subunit; Nuclear factor NF-kappa-B p105 subunit; EBP1; EBP-1; DNAbinding factor KBF1
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| Target Type | Clinical trial Target | ||||
| Gene Name | NFKB1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 28 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Aurin
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Investigative | Compound Info | ||
| Synonyms |
rosolic acid; Corallin; p-Rosolic acid; Aurine; Spirit Aurine; Corallin Spirit Soluble; 4,4'-Dihydroxyfuchsone; Aurin No. 555; C.I. 43800; Pararosolic Acid; UNII-85N4AK3JAU; MFCD00001624; 4-(Bis(4-hydroxyphenyl)methylene)cyclohexa-2,5-dienone; 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one; 2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]-; NSC 7805; 4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one; 85N4AK3JAU; NSC7805; C19H14O3; CI-43800; 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone; 2,5-Cyclohexadien-1-one, 4-(bis(4-hydroxyphenyl)methylene)-; SMR001224399; EINECS 210-041-8; Spectrum_000988; AI3-18245; Spectrum2_000762; Spectrum3_000609; Spectrum4_000904; Spectrum5_001864; Corallin yellow (Salt/Mix); p-Rosolic acid, 85.0%; BSPBio_002118; KBioGR_001368; KBioSS_001468; MLS001359834; MLS002695900; BIDD:ER0176; DivK1c_000400; SCHEMBL590856; SPECTRUM1500762; SPBio_000804; CHEMBL210868; DTXSID2022387; HMS501D22; KBio1_000400; KBio2_001468; KBio2_004036; KBio2_006604; KBio3_001618; NINDS_000400; 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one; HMS1923K11; HMS3058N04; p-Rosolic acid, JIS special grade; KS-00000X6Y; NSC-7805; ZINC3874879; p-Rosolic acid (C.I. 43800); p-Rosolic acid, Dye content 85 %; BDBM50427512; CCG-39006; SBB058277; STL453788; AKOS015903417; MCULE-1450942647; 2, 4-[bis(p-hydroxyphenyl)methylene]-; IDI1_000400; SMP1_000134; 2, 4-[bis(4-hydroxyphenyl)methylene]-; NCGC00095266-01; NCGC00095266-02; NCGC00095266-03; NCI60_041721; ST080685; Aurin (p-Rosolic acid) (C.I. 43800); A0598; A-8703; C14213; Q423995; BRD-K24453427-001-02-9; BRD-K24453427-001-04-5; 4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one; 2,5-Cyclohexadien-1-one, 4-(bis(p-hydroxyphenyl)methylene)-; 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one #; 2,5-Cyclohexadien-1-one, 4-(bis(p-hydroxyphenyl)methylene)- (8CI)
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| Activity |
EC50 = 50000 nM
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[1] | |||
| Compound Name |
2-Hydroxycinnamic acid
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Investigative | Compound Info | ||
| Synonyms |
o-Coumaric acid; trans-2-Hydroxycinnamic acid; 2-Coumaric acid; trans-o-Coumaric acid; trans-o-Hydroxycinnamic acid; 2-Hydroxycinnamate; 2-Coumarate; (E)-o-Hydroxycinnamic acid; trans-2-Hydroxycinnamate; (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid; o-Hydroxy-trans-cinnamic acid; 3-(2-hydroxyphenyl)acrylic acid; (E)-3-(2-Hydroxyphenyl)-2-propenoic acid; (2E)-3-(2-HYDROXYPHENYL)ACRYLIC ACID; 2-Hydroxycinamic acid; (E)-3-(2-hydroxyphenyl)prop-2-enoic acid; trans-2-coumaric acid; (2E)-3-(2-Hydroxyphenyl)-2-propenoic acid; 2-Hydroxycinnamic acid, (E)-; CINNAMIC ACID, o-HYDROXY-, (E)-; UNII-23AU5FZB9C; (E)-2-hydroxycinnamic acid; 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (2E)-; trans-ortho-coumaric acid; MFCD00004379; 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (E)-; 23AU5FZB9C; (2E)-2-hydroxycinnamic acid; 2-Propenoic acid, 3-(2-hydroxyphenyl)-; CHEMBL52564; 2-Hydroxycinnamic acid, predominantly trans; 3-(2-hydroxyphenyl)prop-2-enoic acid; o-coumarate; (E)-3-(2-hydroxyphenyl)acrylic acid; 2-Hydroxy Cinnamic Acid; (E)-3-(2-HYDROXY-PHENYL)-ACRYLIC ACID; 3-(2-hydroxyphenyl)prop-2-enoate; CCRIS 5834; cis-2-hydroxycinnamic acid; EINECS 210-386-4; NSC 32952; BRN 1100900; o-Hydroxycinnamate; 3-(2-Hydroxyphenyl)-2-propenoic acid; trans-o-Coumarate; (2Z)-3-(2-hydroxyphenyl)acrylic acid; ortho-Hydroxycinnamate; PubChem8214; (E)-Coumarinic Acid; (2Z)-3-(2-hydroxyphenyl)acrylate; trans-o-Hydroxycinnamate; (E)-ortho-coumaric acid; o-Hydroxy-trans-cinnamate; (E)-o-Hydroxycinnamicacid; bmse000347; Cinnamic acid, o-hydroxy-; WLN: QV1U1R BQ; SCHEMBL64885; QSPL 150; trans-o-HydroxyzimtsA currencyure; 2-Hydroxycinnamic acid, (2E)-; DTXSID10883240; ZINC895911; ALBB-025832; NSC32952; BBL013048; BDBM50146462; NSC-32952; SBB065726; STK301745; AKOS003790794; CS-W013247; DB01650; MCULE-5451854573; (E)-3-(2-hydroxyphenyl)-acrylic acid; CINNAMIC ACID,2-HYDROXY (TRANS); trans-3-(2-hydroxyphenyl)propenoic acid; AS-12449; ST097457; R1101; C01772; 2-Hydroxycinnamic acid, predominantly trans, 97%; 614H608; 3-(4-OXOQUINAZOLIN-3(4H)-YL)PROPANOICACID; Q7072006; TRANS-2-HYDROXYCINNAMIC ACID; O-COUMARIC ACID; 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (E)- (9CI); F2191-0203; (2E)-3-(2-hydroxyphenyl)acrylic acid predominately trans-; 90E8F55A-AB69-4720-95AF-747C2DCA5471; UNII-2S0H1PX3LM component PMOWTIHVNWZYFI-AATRIKPKSA-N
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| Activity |
IC50 = 50000 nM
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[2] | |||
| Compound Name |
2-Hydroxy-4-(2-sulfo-3',4'-dihydroxybenzhydrylidene)-2,5-cyclohexadiene-1-one
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Investigative | Compound Info | ||
| Synonyms |
Pyrocatecholviolet; Pyrocatecholsulfonephthalein; CHEMBL210574; SCHEMBL10285082; NSC622476; AKOS015950685; ZINC100439037; NSC-622476; Pyrocatechol Violet, suitable for indicator; ST50997616
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| Activity |
EC50 = 50000 nM
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[1] | |||
| Compound Name |
4-[3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322252; BDBM50427531
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
4-[3-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322551; BDBM50427501
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
8-(4-Methoxy-benzoyl)-4-methyl-9-phenyl-furo[2,3-h]chromen-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL605157; ChemDiv1_024319; Oprea1_426600; SCHEMBL10038072; HMS656B09; ZINC1834262; BDBM50331540; STK838033; AKOS005624653; MCULE-5986103736; 8-(4-methoxybenzoyl)-4-methyl-9-phenyl-2H-furo[2,3-h]chromen-2-one; 8-[(4-methoxyphenyl)carbonyl]-4-methyl-9-phenyl-2H-furo[2,3-h]chromen-2-one
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| Activity |
IC50 = 60000 nM
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[2] | |||
| Compound Name |
4-[[2-(3-Tert-butyl-5,9-dimethyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322555; BDBM50427497
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
3-[3-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2321884; BDBM50427502
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
2-[3-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322550; BDBM50427503
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
2-[3-(3-Tert-butyl-5,9-dimethyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]-3-phenylpropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322558; BDBM50427494
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
4-[3-(2,3,5,9-Tetramethyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322275; BDBM50427542
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| Activity |
EC50 = 60000 nM
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[1] | |||
| Compound Name |
3-[[2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetyl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322283; BDBM50427534
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| Activity |
EC50 = 70000 nM
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[1] | |||
| Compound Name |
(4,6-Dichloro-[1,3,5]triazin-2-yl)-(4-isopropyl-phenyl)-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL584211; Oprea1_466875; Oprea1_736146; MLS001209217; SCHEMBL8973767; HMS2823E24; 4,6-dichloro-N-(4-propan-2-ylphenyl)-1,3,5-triazin-2-amine; BDBM50300852; AKOS009154781; SMR000515619; 4,6-dichloro-N-(4-isopropylphenyl)-1,3,5-triazin-2-amine
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| Activity |
IC50 = 74400 nM
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[3] | |||
| Compound Name |
2-[4-[3-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]phenyl]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322553; BDBM50427499
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| Activity |
EC50 = 80000 nM
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[1] | |||
| Compound Name |
2-[[2-(4-Methyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetyl]amino]-3-phenylpropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322276; BDBM50427541
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| Activity |
EC50 = 80000 nM
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[1] | |||
| Compound Name |
3-[3-(2,3,5,9-Tetramethyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322255; BDBM50427527
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| Activity |
EC50 = 80000 nM
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[1] | |||
| Compound Name |
2-[[2-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322545; BDBM50427508
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| Activity |
EC50 = 80000 nM
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[1] | |||
| Compound Name |
2-[3-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]-3-phenylpropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322549; BDBM50427504
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
2-[3-(4-Methyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanoylamino]-3-phenylpropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322279; BDBM50427538
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
3-[3-(4-Methyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322280; BDBM50427537
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
3-[3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanoylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322251; BDBM50427532
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
4-[[2-(2,3,5,9-Tetramethyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322273; BDBM50427544
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
4-[[2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetyl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322250; BDBM50427533
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
3-[[2-(4-Methyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetyl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322277; BDBM50427540
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
Chrome Azurol S
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Investigative | Compound Info | ||
| Synonyms |
Mordant Blue 29; Alberon; Antracromo Azurol BS; Chromine Sky Blue S; Chromoxane Pure Blue BLD; C.I. Mordant Blue 29; Chrome Azurol; Chromeazurol S; C.I. 43825; MFCD00001615; EINECS 216-787-0; NSC 56431; NSC 623549; C23H13Cl2O9S.3Na; CHEMBL377545; DTXSID50889367; Chromeazurol S, Dye content 50 %; SBB006521; AKOS004901558; AKOS015903601; AKOS024380590; AKOS025116645; D0241; ST51026771; Z3642; C.I. Mordant Blue 29, trisodium salt (8CI)
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| Activity |
EC50 = 100000 nM
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[1] | |||
| Compound Name |
4,6-Dichloro-N-(4-chlorophenyl)-1,3,5-triazin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL577302; (4-Chloro-phenyl)-(4,6-dichloro-[1,3,5]triazin-2-yl)-amine; (4-CHLORO-PHENYL)-(4,6-DICHLORO-(1,3,5)TRIAZIN-2-YL)-AMINE; SCHEMBL3500246; ZINC301169; BDBM50300850; AKOS003672242; MCULE-3853278753; SR-01000195871; 2,4-Dichloro-6-(4-chloroanilino)-1,3,5-triazine; SR-01000195871-1; 4,6-dichloro-N-(4-chlorophenyl)-[1,3,5]triazine-2-amine; (4-chloro-phenyl)-(4,6-dichloro-[1,3,5]triazin-2-yl)amine; (4-chlorophenyl)-(4,6-dichloro-[1,3,5]triazin-2-yl)-amine; 1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4-chlorophenyl)-
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| Activity |
IC50 = 110000 nM
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[3] | |||
| Compound Name |
2,4-Dichloro-6-(3-nitroanilino)-1,3,5-triazine
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Investigative | Compound Info | ||
| Synonyms |
NSC648495; 4,6-Dichloro-N-(3-nitrophenyl)-1,3,5-triazin-2-amine; CHEMBL577265; (4,6-Dichloro-[1,3,5]triazin-2-yl)-(3-nitro-phenyl)-amine; MLS000688693; SCHEMBL5031319; HMS2603E17; ZINC369693; BDBM50300848; AKOS000594048; NSC-648495; NCI60_016842; SMR000284694; SR-01000317044; SR-01000317044-1; 4,6-Dichloro-2-(3-nitrophenylamino)-1,3,5-triazine; 4,6-Dichloro-N-(3-nitrophenyl)-1,3,5-triazin-2-amine #; 2,4-Dichloro-6-(3-(hydroxy(oxido)amino)anilino)-1,3,5-triazine
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| Activity |
IC50 = 119000 nM
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[3] | |||
| Compound Name |
Hymecromone
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Investigative | Compound Info | ||
| Synonyms |
4-methylumbelliferone; 7-HYDROXY-4-METHYLCOUMARIN; 7-Hydroxy-4-methyl-2H-chromen-2-one; Imecromone; beta-Methylumbelliferone; Cholestil; Mendiaxon; 4-Methyl-7-hydroxycoumarin; Bilcolic; Bilicante; Cantabilin; Cantabiline; Coumarin 4; Cholonerton; Hymecromon; Crodimon; Eurogale; Medilla; Cumarote-C; Omega 127; Pilot 447; 2H-1-Benzopyran-2-one, 7-hydroxy-4-methyl-; 4-Methylumbelliferon; Himecromona; Hymecromonum; 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one; NSC 9408; NSC 19026; 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran; LM 94; 4-Methylumbelliferone (4-MU); Coumarin, 7-hydroxy-4-methyl-; 7-hydroxy-4-methylchromen-2-one; 7-hydroxy-4-methyl-chromen-2-one; 7-hydroxy-4-methyl-coumarin; 2H-1-Benzopyran, 7-hydroxy-4-methyl-2-oxo-; 2H-1-Benzopyren-2-one, 7-hydroxy-4-methyl-; 7-Hydroxy-4-methyl-2-oxo-3-chromene; UNII-3T5NG4Q468; NSC9408; LM-94; NSC19026; MFCD00006866; .beta.-Methylumbelliferone; 7-hydroxy-4-methyl coumarin; 4-Methyl-7-hydroxy-coumarin; CHEMBL12208; Resocyanine; 2H-1-Benzopyran-2-one,7-hydroxy-4-methyl-; 3T5NG4Q468; NSC-9408; NSC-19026; NCGC00016345-01; DSSTox_CID_5670; DSSTox_RID_77877; DSSTox_GSID_25670; Imecromone [DCIT]; METHYLUMBELLIFERONE, BETA; WLN: T66 BOVJ E1 IQ; Cholspasmin; Hymechrome; 7-Hydroxy-4-methylcoumarin, 97%; Hymecromonum [INN-Latin]; Himecromona [INN-Spanish]; SMR000471886; 4-Methylumbelliferon [Czech]; 4 Methylumbelliferone; CCRIS 5926; EINECS 201-986-7; BRN 0142217; Himecol; AI3-08085; Biliton H; Hymecromohe,(S); Cantabiline (TN); Hymecromone [USAN:INN:BAN:JAN]; A-Methylumbelliferone; 4-methyl umbelliferone; 4-Methyl-umbelliferone; Coumarin derivative, 3b; Maybridge1_002078; Prestwick0_000901; Prestwick1_000901; Prestwick2_000901; Prestwick3_000901; Umbelliferone, 4-methyl-; 7-Hydroxy-4-methlcoumarin; Methylumbelliferone, .beta.; 4-methyl-7-hydroxy-cumarin; 7-hydroxy-4-methyl-coumari; SCHEMBL24150; BSPBio_000742; 5-18-01-00439 (Beilstein Handbook Reference); 7-hydroxy-4-methyl coumarine; KSC498C0B; MLS001074671; MLS004491718; 4-Methyl-7-hydroxyl Coumarin; SPBio_002941; 4-Methylumbelliferone - 4-MU; AMBZ0098; BPBio1_000818; MEGxp0_001898; 7-hydroxy-4-methyl-2-coumarin; 4-Methylumbelliferone, >=98%; DTXSID8025670; ACon1_002401; cid_5280567; CTK2G4039; CTK3J8100; HMS547G10; Hymecromone (JP17/USAN/INN); ZINC58121; 7-Hydroxy-4-methyl-2-chromenone; HMS1570F04; HMS2097F04; HMS2267L19; HMS3264E04; HMS3655L16; HMS3714F04; Pharmakon1600-01506174; 4-methyl-7-oxidanyl-chromen-2-one; BCP06770; HY-N0187; KS-00000JR8; Tox21_110385; Tox21_300915; ANW-43852; BBL000531; BDBM50022178; CCG-47894; NSC760397; s2256; SBB009085; STK364326; 7-Hydroxy-4-methyl-2H-2-chromenone; AKOS000119370; Tox21_110385_1; AM85958; CS-7560; DB07118; MCULE-3913656430; NSC-760397; 7-hydroxy-4-methyl-1-benzopyran-2-one; NCGC00016345-02; NCGC00016345-03; NCGC00016345-04; NCGC00016345-05; NCGC00016345-08; NCGC00016345-09; NCGC00169880-01; NCGC00169880-02; NCGC00257522-01; 7-Hydroxy-4-methyl-2H-chromen-2-one #; AC-22306; AK-72865; AS-13247; BR-72865; NCI60_042099; SC-25664; DB-029370; 2-Hydroxy-4-methyl-7H-1-benzopyran-7-one; AB00443536; B6001; FT-0602257; FT-0658701; FT-0660634; M0453; ST50102505; SW197287-3; 7H-1-Benzopyran-7-one, 2-hydroxy-4-methyl-; A-8711; C03081; D00170; M-5410; AB00443536_08; A843515; Q904431; SR-01000637483; SR-01000637483-1; SR-01000637483-3; BRD-K46424862-001-02-6; BRD-K46424862-001-04-2; F0849-0318; F1918-0038
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| Activity |
IC50 = 200000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 31 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4,6-Dichloro-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL579399; (4,6-Dichloro-[1,3,5]triazin-2-yl)-(4-nitro-phenyl)-amine; SCHEMBL8913032; DTXSID80274585; ZINC3894054; BDBM50300849; STK764245; AKOS000565451; ST4061354; 2,4-Dichloro-6-(4-nitroanilino)-1,3,5-triazine; 2,4-DICHLORO-6-(P-NITROANILINO)-S-TRIAZINE; (4,6-dichloro(1,3,5-triazin-2-yl))(4-nitrophenyl)amine; 4,6-Dichloro-N-(4-nitrophenyl)-1,3,5-triazin-2-amine #
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[3] | |||
| Compound Name |
2-[4-[[2-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322548; BDBM50427505
Click to Show/Hide
|
||||
| Activity |
EC50 = 530000 nM
|
[1] | |||
| Compound Name |
3-[3-(2,3,5-Trimethyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2321881; BDBM50427529
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[1] | |||
| Compound Name |
2-[[2-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1829845; BDBM50427509; MCULE-2495064752
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[1] | |||
| Compound Name |
4-[[[2-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322547; BDBM50427506
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[1] | |||
| Compound Name |
3-[[2-(2,3,5,9-Tetramethyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322254; BDBM50427528
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[1] | |||
| Compound Name |
3-Phenyl-2-[[2-(2,3,5,9-tetramethyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322272; BDBM50427545
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[1] | |||
| Compound Name |
4-(2-(3-(Tert-butyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetamido)butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322557; ZINC2112529; BDBM50427495; STL516087; AKOS030501593; MCULE-9063168866; 4-{[(3-tert-butyl-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetyl]amino}butanoic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[1] | |||
| Compound Name |
4-[[3-(3-Tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322552; BDBM50427500
Click to Show/Hide
|
||||
| Activity |
EC50 = 670000 nM
|
[1] | |||
| Compound Name |
4-[[2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetyl]amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322261; BDBM50427521
Click to Show/Hide
|
||||
| Activity |
EC50 = 700000 nM
|
[1] | |||
| Compound Name |
3-[[2-(2,3,5-Trimethyl-7-oxofuro[3,2-g]chromen-6-yl)acetyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322253; BDBM50427530
Click to Show/Hide
|
||||
| Activity |
EC50 = 700000 nM
|
[1] | |||
| Compound Name |
3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-(3-hydroxyphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322262; BDBM50427520
Click to Show/Hide
|
||||
| Activity |
EC50 = 700000 nM
|
[1] | |||
| Compound Name |
2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-(4-hydroxyphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322257; BDBM50427525
Click to Show/Hide
|
||||
| Activity |
EC50 = 700000 nM
|
[1] | |||
| Compound Name |
2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-[4-(methanesulfonamido)phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322260; BDBM50427522
Click to Show/Hide
|
||||
| Activity |
EC50 = 700000 nM
|
[1] | |||
| Compound Name |
4-[3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanoylamino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322249; BDBM50427514
Click to Show/Hide
|
||||
| Activity |
EC50 = 700000 nM
|
[1] | |||
| Compound Name |
N-[(2-Chlorophenyl)methyl]-2-(4,6,9-trimethyl-2-oxofurano[3,2-g]chromen-3-yl)a cetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322269; ZINC4743973; BDBM50427548; EiM17-00071; AKOS001891746; MCULE-1749648855; ST50328136; N-(2-chlorobenzyl)-2-(3,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetamide
Click to Show/Hide
|
||||
| Activity |
EC50 = 800000 nM
|
[1] | |||
| Compound Name |
(3-Tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322544; (3-tert-Butyl-5-methyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid; ALBB-015687; ZINC5235542; 2-(3-tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)acetic acid; BBL030159; BDBM50427510; MFCD03851427; STK713388; AKOS001893035; MCULE-4135273532; R8036; SR-01000149069; SR-01000149069-1; 2-(3-(tert-Butyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 800000 nM
|
[1] | |||
| Compound Name |
(3-Tert-butyl-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322554; (3-tert-Butyl-5,9-dimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid; ChemDiv3_014762; 2-(3-tert-butyl-5,9-dimethyl-7-oxofuro[3,2-g]chromen-6-yl)acetic acid; HMS1514O22; ALBB-015610; ZINC5235537; BBL030156; BDBM50427498; MFCD03850700; STK713385; AKOS001892524; MCULE-9201644044; IDI1_030560; VS-09644; R8033; 2-(3-(tert-Butyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid; 2-{3-tert-butyl-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl}acetic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 800000 nM
|
[1] | |||
| Compound Name |
3-Phenyl-2-[3-(2,3,5,9-tetramethyl-7-oxofuro[3,2-g]chromen-6-yl)propanoylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322274; BDBM50427543
Click to Show/Hide
|
||||
| Activity |
EC50 = 1000000 nM
|
[1] | |||
| Compound Name |
N-(4-Acetamidophenyl)-3-(4,11-dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322266; BDBM50427516
Click to Show/Hide
|
||||
| Activity |
EC50 = 1000000 nM
|
[1] | |||
| Compound Name |
2-[[2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetyl]amino]-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322282; BDBM50427535
Click to Show/Hide
|
||||
| Activity |
EC50 = 1000000 nM
|
[1] | |||
| Compound Name |
3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-[4-(methanesulfonamido)phenyl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322248; BDBM50427515
Click to Show/Hide
|
||||
| Activity |
EC50 = 1000000 nM
|
[1] | |||
| Compound Name |
N-(4-Aminophenyl)-3-(4,11-dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322265; BDBM50427517
Click to Show/Hide
|
||||
| Activity |
EC50 = 3000000 nM
|
[1] | |||
| Compound Name |
2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-(3-hydroxyphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322256; BDBM50427526
Click to Show/Hide
|
||||
| Activity |
EC50 = 3000000 nM
|
[1] | |||
| Compound Name |
2-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-[3-(trifluoromethyl)phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322258; BDBM50427524
Click to Show/Hide
|
||||
| Activity |
EC50 = 3000000 nM
|
[1] | |||
| Compound Name |
3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-(4-hydroxyphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322263; BDBM50427519
Click to Show/Hide
|
||||
| Activity |
EC50 = 3000000 nM
|
[1] | |||
| Compound Name |
N-(4-Acetamidophenyl)-2-(4,11-dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322259; BDBM50427523
Click to Show/Hide
|
||||
| Activity |
EC50 = 3000000 nM
|
[1] | |||
| Compound Name |
3-(3-Tert-butyl-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(2-chlorobenzyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322268; ZINC9198964; BDBM50427549; EiM07-19336; STL461994; AKOS001518752; MCULE-3386541236
Click to Show/Hide
|
||||
| Activity |
EC50 = 4000000 nM
|
[1] | |||
| Compound Name |
2-(3-Tert-butyl-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(2-chlorobenzyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322556; BDBM50427496; EiM07-20180; STL462651; ZINC11867553; AKOS001518656; MCULE-9181224887
Click to Show/Hide
|
||||
| Activity |
EC50 = 5000000 nM
|
[1] | |||
| Compound Name |
(2,3,5,9-Tetramethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322271; 2-{2,3,5,9-tetramethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl}acetic acid; 2-(2,3,5,9-tetramethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid; ZINC4042658; BBL030056; BDBM50427546; STL372133; AKOS015955798; MCULE-3192543705; VS-09586; SR-01000149065; SR-01000149065-1
Click to Show/Hide
|
||||
| Activity |
EC50 = 6000000 nM
|
[1] | |||
| Compound Name |
3-(4,11-Dimethyl-2-oxo-6,7,8,9-tetrahydro-[1]benzofuro[3,2-g]chromen-3-yl)-N-[3-(trifluoromethyl)phenyl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322264; BDBM50427518
Click to Show/Hide
|
||||
| Activity |
EC50 > 10000000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Psoralen derivatives as inhibitors of NF-B/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation. J Med Chem. 2013 Mar 14;56(5):1830-42. | ||||
| REF 2 | Virtual screening against nuclear factor B (NF-B) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-B dependent biological functions involved in cystic fibrosis. Bioorg Med Chem. 2010 Dec 1;18(23):8341-9. | ||||
| REF 3 | A new small molecule that directly inhibits the DNA binding of NF-kappaB. Bioorg Med Chem. 2009 Jul 15;17(14):5293-7. | ||||
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