Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T36959 | Target Info | |||
| Target Name | Activin receptor-like kinase-1 (ACVRL1) | ||||
| Synonyms |
Serine/threonine-protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; ACVRLK1; ACVRL1
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| Target Type | Clinical trial Target | ||||
| Gene Name | ACVRL1 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-Amino-7-methyl-4-[(4-methylphenyl)methylamino]-9H-pyrimido[4,5-b]indol-6-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098682; BDBM50242512
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2708-2712. | ||||
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