Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T36612 | Target Info | |||
| Target Name | Peptidyl arginine deiminase type III (PADI3) | ||||
| Synonyms |
Protein-arginine deiminase type-3; Protein-arginine deiminase type III; Peptidylarginine deiminase III; PDI3; PAD3
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| Target Type | Literature-reported Target | ||||
| Gene Name | PADI3 | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
F-Amidine (trifluoroacetate salt)
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1910973; SCHEMBL18730598
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| Activity |
Ki = 293000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | The development of N-alpha-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-alpha-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. J Med Chem. 2011 Oct 13;54(19):6919-35. | ||||
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