Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T31788 | Target Info | |||
| Target Name | Monocarboxylate transporter 4 (SLC16A3) | ||||
| Synonyms |
Solute carrier family 16 member 3; MCT4; MCT 4
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| Target Type | Literature-reported Target | ||||
| Gene Name | SLC16A3 | ||||
| Biochemical Class | Major facilitator | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 3 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
NPPB
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Investigative | Compound Info | ||
| Synonyms |
5-Nitro-2-(3-phenylpropylamino)benzoic acid; 107254-86-4; UNII-3A35O9G3YZ; 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid; 3A35O9G3YZ; CHEBI:34457; Benzoic acid,5-nitro-2-[(3-phenylpropyl)amino]-; Benzoic acid, 5-nitro-2-((3-phenylpropyl)amino)-; 5-NITRO-2-PHENYLPROPYLAMINOBENZOIC ACID [NPPB]; 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID; 5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB); SR-01000075336; HOE-144; HOE 144; Tocris-0593; Spectrum_001814; ACMC-20c9kv; AC1L1IEV; Spectrum4_000338; Spectrum2_001477; HOE 144; 5-nitro-2-(3-phenylpropylamino) benzoic acid
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| Activity |
IC50 = 240000 nM
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[1] | |||
| Compound Name |
isobutylmethylxanthine
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Investigative | Compound Info | ||
| Synonyms |
3-Isobutyl-1-methylxanthine; IBMX; 28822-58-4; 1-METHYL-3-ISOBUTYLXANTHINE; Methylisobutylxanthine; 3-Isobutyl-1-methyl-1H-purine-2,6(3H,7H)-dione; Xanthine, 3-isobutyl-1-methyl-; 3-Isobutyl-1-methyxanthine; 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-; Methyl-isobutylxanthine; 3-isobutyl-1-methylxanthine (ibmx); UNII-TBT296U68M; 3-Isobutyl 1-methylxanthine; NSC 165960; CCRIS 4290; CHEBI:34795; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione; 3-isobutyl-1-methyl-7H-xanthine; methylisobutylxanthine; 3-Isobutyl-1-methyl-3,9-dihydro-purine-2,6-dione; 3-ISOBUTYL-1-METHYLXANTHINE
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| Activity |
IC50 = 970000 nM
|
[1] | |||
| Compound Name |
alpha-Cyano-4-hydroxycinnamic acid
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Investigative | Compound Info | ||
| Synonyms |
alpha-Cyano; a-Cyano-4-hydroxycinnamic acid; 2-Cyano-3-(4-hydroxyphenyl)acrylic acid; (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid; alpha-CHCA; alpha-cyano-4-hydroxy-cinnamic acid; (E)-2-cyano-3-(4-hydroxyphenyl)acrylic acid; MFCD00004204; 1-carboxy-1-cyano-2-(4-hydroxyphenyl)ethylene; Q63391607; 4-HCCA; alpha-CCA; 2-Propenoic acid, 2-cyano-3-(4-hydroxyphenyl)-; Spectrum5_001633; 2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid; SCHEMBL26825; BSPBio_002260; MLS002207285; CHEMBL76602; (E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid; BDBM4350; HMS500K21; DTXSID501018295; ZINC155109; BBL103553; CCG-39475; GEO-00838; s8612; SBB057160; STL557363; .alpha.-Cyano-4-hydroxycinnamic acid; AKOS000145566; IDI1_000219; NCGC00094622-01; NCGC00094622-02; alpha-Cyano-4-hydroxybenzenepropenoic acid; alpha-Cyano-4-hydroxycinnamic acid, 97%; alpha-Cyano-4-hydroxycinnamic acid, 99%; benzylidenemalononitrile (BMN) deriv. 34; BS-16413; SMR001306800; 2-Cyano-3-(4-hydroxyphenyl)propenoic acid; HY-107641; CS-0029043; ST50997515; A819766; (E)-2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid; BRD-K60302405-001-02-9; BRD-K60302405-001-04-5; (2E)-2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid #; alpha-Cyano-4-hydroxycinnamic acid, >=98% (TLC), powder; alpha-Cyano-4-hydroxycinnamic acid, purum, >=99.0% (HPLC); alpha-Cyano-4-hydroxycinnamic acid, suitable for MALDI-TOF MS; alpha-Cyano-4-hydroxycinnamic acid, matrix substance for MALDI-MS, Ultra pure
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| Activity |
IC50 = 991000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol. 2000 Dec 1;529 Pt 2(Pt 2):285-93. | ||||
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