Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T30372 | Target Info | |||
| Target Name | Trypanosoma Cruzipain (Trypano CYSP) | ||||
| Synonyms |
Cruzaine; Major cysteine proteinase
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| Target Type | Successful Target | ||||
| Gene Name | Trypano CYSP | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 108 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Methylene blue
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Approved | Compound Info | ||
| Synonyms |
methylene blue; 61-73-4; Methylthioninium chloride; Swiss Blue; Chromosmon; Methylene Blue N; Methylenium ceruleum; Urolene blue; Methylene Blue chloride; Solvent blue 8; Bleu de methylene; Methylene Blue G; Methylene Blue A; External Blue 1; Methylene Blue D; Methylene Blue B; Methylene Blue anhydrous; CI Basic Blue 9; Methylene Blue ZF; Methylene Blue SP; Methylene Blue NZ; Methylene Blue BX; Methylene Blue BD; Methylene Blue SG; Tetramethylene Blue; Methylene Blue ZX; Methylene Blue FZ; Methylene Blue BP; Calcozine; 3,7-Bis-dimethylamino-phenothiazin-5-ylium
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| Activity |
IC50 = 55000 nM
|
[1] | |||
| Compound Name |
Raloxifene
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Approved | Compound Info | ||
| Synonyms |
Raloxifene (extended-release, CDT)
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| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
Fenofibrate
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Approved | Compound Info | ||
| Synonyms |
Ankebin; Antara; Controlip; Durafenat; Elasterate; Elasterin; FNF; Fenobeta; Fenobrate; Fenofanton; Fenofibrato; Fenofibratum; Fenogal; Fenoglide; Fenomax; Fenotard; Finofibrate; Fulcro; Lipanthyl; Lipantil; Liparison; Lipidex; Lipidil; Lipifen; Lipirex; Lipoclar; Lipofen; Lipofene; Liposit; Lipsin; Lofibra; Luxacor; Nolipax; Pharmavit; Phenofibrate; Procetofen; Procetofene; Proctofene; Protolipan; Secalip; Sedufen; Supralip; Tricor; Triglide; AbZ Brand of Procetofen; Abbott Brand of Procetofen; Aliud Brand of Procetofen; Antara Micronized Procetofen; Anto Brand of Procetofen; Apo Feno Micro; Apo Fenofibrate; Apotex Brand of Procetofen; Azupharma Brand of Procetofen; Betapharm Brand of Procetofen; Bouchara Brand of Procetofen; Ct Arzneimittel Brand of Procetofen; Fenofibrat AL; Fenofibrat AZU; Fenofibrat AbZ; Fenofibrat FPh; Fenofibrat Heumann; Fenofibrat Hexal; Fenofibrat Stada; Fenofibrat ratiopharm; Fenofibrat von ct; Fenofibrate Debat; Fenofibrate MSD; Fournier Brand of Procetofen; GNR Pharma Brand of Procetofen; Gate Brand of Procetofen; Gen Fenofibrate; Genpharm Brand of Procetofen; Heumann Brand of Procetofen; Hexal Brand of Procetofen; Knoll Brand of Procetofen; Lichtenstein Brand of Procetofen; Lipidil Micro; Lipidil Supra; Lipidil Ter; MTW Brand of Procetofen; MTW Fenofibrat; Merck dura Brand of Procetofen; Novartis Brand of Procetofen; Novo Fenofibrate; Novopharm Brand of Procetofen; Nu Fenofibrate; Nu Pharm Brand of Procetofen; PMS Fenofibrate Micro;Pharmascience Brand of Procetofen; Procetofen Reliant Brand; Q Pharm Brand of Procetofen; Ratiopharm Brand of Procetofen; Reliant Brand of Procetofen; Schering Plough Brand of Procetofen; Stadapharm Brand of Procetofen; United Drug Brand of Procetofen; F 6020; LF 178; LF178; AZU, Fenofibrat; Antara (TN); Antara (micronized); Apo-Fenofibrate; CIP-Fenofibrate; Ct-Arzneimittel Brand of Procetofen; Debat, Fenofibrate; FENOFIBRATE (MICRONIZED); Fenofibrat-ratiopharm; Fenofibrate IDD-P; Fenofibrate [INN:BAN]; Fenofibrato [INN-Spanish]; Fenofibratum [INN-Latin]; Fenogal (TN); GNR-Pharma Brand of Procetofen; GRS-027; Gen-Fenofibrate; Heumann, Fenofibrat; Hexal, Fenofibrat; LCP-Feno; LCP-FenoChol; LF-178; Lipanthyl (TN); Lipantil (TN); Lipidil (TN); Lipidil-Ter; Lipofen (TN); Lofibra (TN); MTW-Fenofibrat; Micronized Procetofen, Antara; Novo-Fenofibrate; Nu-Fenofibrate; Nu-Pharm Brand of Procetofen; PMS-Fenofibrate Micro; Procetofen, Antara Micronized; Q-Pharm Brand of Procetofen; Schering-Plough Brand of Procetofen; Stada, Fenofibrat; TRICOR (MICRONIZED); Tricor (TN); Triglide (TN); Trilipix (TN); Apo-Feno-Micro; Fenocor-67 (TN); Fenofibrate (JAN/INN); Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate; Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate; Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate
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| Activity |
IC50 = 61000 nM
|
[1] | |||
| Compound Name |
Pranlukast
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Approved | Compound Info | ||
| Synonyms |
Azlaire; Azlaire (TN); Pranlukast (INN); N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
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| Activity |
IC50 = 68000 nM
|
[1] | |||
| Compound Name |
Cinnarizine
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Approved | Compound Info | ||
| Synonyms |
Aplactan; Aplexal; Apotomin; Artate; Carecin; Cerebolan; Cinaperazine; Cinarizina; Cinarizine; Cinazyn; Cinnacet; Cinnageron; Cinnarizinum; Corathiem; Denapol; Dimitron; Dimitronal; Eglen; Folcodal; Giganten; Glanil; Hilactan; Ixertol; Katoseran; Labyrin; Lazeta; Libotasin; Marisan; Midronal; Mitronal; Olamin; Processine; Sedatromin; Senoger; Sepan; Siptazin; Spaderizine; Stugeron; Stutgeron; Stutgin; Toliman; Votegol; Zepamol; Cinnarizine Stugeron; C 5270; MD 516; R 1575; R 516; Cero-Aterin; Cinarizina [INN-Spanish]; Cinnarizinum [INN-Latin]; R-516; Stugeron (TN); Stunarone (TN); Cinnarizine (JAN/USAN/INN); Cinnarizine [USAN:INN:BAN:JAN]; N-Benzhydryl-N'-cinnamylpiperazine; 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine; 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine; 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine; 1-Benzhydryl-4-cinnamylpiperazin; 1-Cinnamyl-4-(diphenylmethyl)piperazine; 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine; 1-trans-Cinnamyl-4-diphenylmethylpiperazine
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| Activity |
IC50 = 124000 nM
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[1] | |||
| Compound Name |
VRX496
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Approved | Compound Info | ||
| Synonyms |
Nelfinavir; nelfinavir; 159989-64-7; Viracept; Nelfinavir [INN:BAN]; AG1343; UNII-HO3OGH5D7I; AG-1343; C32H45N3O4S; NELFINAVIR MESYLATE AG1343; Viracept (TN); HO3OGH5D7I; CHEBI:7496; AG 1343; NLF; 1UN; 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE; (3S-(2(2S*,3S*),3alpha,4abeta,8abeta))-N-(1,1-Dimethylethyl)decahydro-2-(2-hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-4-(phenylthio)butyl)-3-isoquinolinecarboxamide; NFV; NFV; Nelfinavir Monomethane Sulfonate; AG1346; Nelfinavir (INN); Nelfinavir [BAN:INN]; AG1343 (*Mesylate salt*); Viracept (TM)(*Mesylate salt*); Met-SDF-1beta & Nelfinavir; Met-Stromal Cell-derived Factor-1beta (Human) & Nelfinavir; (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide
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| Activity |
IC50 = 144000 nM
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[1] | |||
| Compound Name |
B-Lactams
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Approved | Compound Info | ||
| Synonyms |
Luteolin; luteolin; 491-70-3; Luteolol; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; Luteoline; Digitoflavone; Flacitran; Weld Lake; Cyanidenon 1470; Salifazide; Yama kariyasu; 5,7,3',4'-Tetrahydroxyflavone; UNII-KUX1ZNC9J2; CI Natural Yellow 2; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-; 7-Tetrahydroxyflavone; CCRIS 3790; EINECS 207-741-0; KUX1ZNC9J2; CHEMBL151; BRN 0292084; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
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| Activity |
IC50 = 155700 nM
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[3] | |||
| Compound Name |
Genistein
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Phase 2/3 | Compound Info | ||
| Synonyms |
Bonistein; GEN; Genestein; Genisteol; Genisterin; Prunetol; Sophoricol; Differenol A; G 6649; G10000; IN1327; NPI 031L; STO514; TNP00151; GENISTEIN (ENDOCRINE DISRUPTER); Lactoferrin-genistein; PTI G4660 (Genistein); PTI-G4660; SIPI 807-1; C.I. 75610; SIPI-9764-I; ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)); 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; ,5,7-Trihydroxyisoflavone; 4',5, 7-Trihydroxyisoflavone; 4',5,7-Trihydroxy isoflavone; 4',5,7-Trihydroxyisoflavone; 4,5,7-Trihydroxyiso-flavone; 4,6,7-Trihydroxyisoflavone; 5,7,4'-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
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| Activity |
IC50 = 82700 nM
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[3] | |||
| Compound Name |
PMID26394986-Compound-22
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Patented | Compound Info | ||
| Activity |
IC50 = 126000 nM
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[1] | |||
| Compound Name |
AM-404
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Investigative | Compound Info | ||
| Synonyms |
AM 404; AM-404; 183718-77-6; am404; UNII-XVJ94H0U21; 198022-70-7; CHEMBL39878; XVJ94H0U21; CPD000449274; (5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide; N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide; SMR000449274; SR-01000597390; N-(4-Hydroxyphenyl)-arachidonylamide; N-(4-Hydroxyphenyl)arachidonylamide; N-(4-Hydroxyphenyl)arachidonoyl amide; NCGC00025010-01; Tocris-1116; AC1O7GXA; 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-; N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
AZ10417808
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Investigative | Compound Info | ||
| Synonyms |
AZ-10417808; AZ 10417808
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
3,7,3',4'-TETRAHYDROXYFLAVONE
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Investigative | Compound Info | ||
| Synonyms |
Fisetin; 528-48-3; 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one; 5-Desoxyquercetin; Fustel; Cotinin; Viset; 3,3',4',7-Tetrahydroxyflavone; Fisetholz; Superfustel; Fustet; Fietin; Junger fustik; 3,7,3',4'-Tetrahydroxyflavone; Ventin sumach; Zante fustic; Young fustic; Superfustel K; Ungarisches gelbholz; CI Natural Brown 1; Young fustic crystals; Bois bleu de Honqrie; BOIS bleude honqrie; CI 75620; NSC 407010; NSC 656275; 5-Deoxyquercetin; 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one; Natural Brown 1; FISETIN
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
ELLAGIC ACID
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Investigative | Compound Info | ||
| Synonyms |
ellagic acid; 476-66-4; Benzoaric acid; Lagistase; Eleagic acid; Alizarine Yellow; Elagostasine; 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione; Ellagic acid dihydrate; Llagic acid; Acide ellagique; Acido elagico; Acidum ellagicum; C.I. 55005; Gallogen (VAN); Gallogen (astringent); C.I. 75270; Ellagate; Ellagic acid [INN:DCF]; UNII-19YRN3ZS9P; Acido elagico [INN-Spanish]; CCRIS 774; Gallogen, astringent; Acide ellagique [INN-French]; Acidum ellagicum [INN-Latin]; MLS000069632; C14H6O8; EINECS 207-508-3; NSC407286; NSC 40728
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| Activity |
IC50 = 64000 nM
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[4] | |||
| Compound Name |
NSC-119911
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Investigative | Compound Info | ||
| Synonyms |
NSC119911; CHEMBL258670; CHEMBL3260988; NSC-119911; MLS-0111616.0001; AC1OBGP2; AC1NTI1U; AC1NS1JN; SCHEMBL2846330; SCHEMBL2846323; CHEMBL502775; (9Z)-9-(3,3-dihydroxyprop-2-enylidene)-5,6-dihydroxyxanthene-3,4-dione; ZINC3954334; BDBM50011357; NSC158917; NCI119911; CCG-36604; BDBM50373125; NSC-158917; 9-(3,3-dihydroxyprop-2-enylidene)-5,6-dihydroxyxanthene-3,4-dione; (E)-3-(3,4,5-trihydroxy-6-oxo-xanthen-9-yl)prop-2-enoic acid; 2-Propenoic acid, 3-(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)-, (2E)-
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| Activity |
IC50 = 95000 nM
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[4] | |||
| Compound Name |
Clopidogrel
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Phase 2 Trial | Compound Info | ||
| Synonyms |
(S)-Clopidogrel; Plavix; (+)-Clopidogrel; Clopidogrel [INN:BAN]
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| Activity |
IC50 = 123000 nM
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[1] | |||
| Compound Name |
[(5-Methyl-2-oxoindol-3-yl)amino]thiourea
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Investigative | Compound Info | ||
| Synonyms |
MLS000777315; CHEMBL119345; SMR000413706; (3Z)-5-methyl-1H-indole-2,3-dione 3-thiosemicarbazone; BDBM78901; cid_5403661; 5-methylisatin-3-thiosemicarbazone; HMS2772N05; BDBM50133628; STK838709; AKOS001046258; AKOS016868161; AKOS030661334; ZINC100563870; MCULE-7063657725; [(5-methyl-2-oxo-3-indolyl)amino]thiourea; [(2-keto-5-methyl-indol-3-yl)amino]thiourea; 1-[(5-methyl-2-oxidanylidene-indol-3-yl)amino]thiourea; 2-Oxo-5-methyl-2,3-dihydro-1H-indole-3-onethiosemicarbazone; (2Z)-2-(5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinecarbothioamide; 2-(5-methyl-2-oxo-1,2-dihydro-3H-indol-3-yliden)-1-hydrazinecarbothioamide
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| Activity |
IC50 = 50000 nM
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[5] | |||
| Compound Name |
5(E)-[2-(Phenylsulfonyl)vinyl]benzo[1,2-c]1,2,5-oxadiazole N1-oxide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL238429; BDBM50225450
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-[(2Z)-2-[(3-Ethoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)imino]-4-oxo-3-prop-2-enyl-1,3-thiazolidin-5-yl]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828195; BDBM50187498
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| Activity |
IC50 = 50000 nM
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[7] | |||
| Compound Name |
5(Z)-[2-(Phenylsulfonyl)vinyl]benzo[1,2-c]1,2,5-oxadiazole N1-oxide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL391827; BDBM50225446
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid 2-amino-6-fluorobenzylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL550836; BDBM50295149
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| Activity |
IC50 = 52000 nM
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[8] | |||
| Compound Name |
(2E)-N'-[(E)-2-Hydroxybenzylidene]-3-phenylprop-2-enohydrazide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2042780; BDBM50386185; (2E)-N'-[(E)-2-Hydroxybenzylidene]-3-phenylprop- 2-enohydrazide
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| Activity |
IC50 = 52200 nM
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[9] | |||
| Compound Name |
Aurintricarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
Aluminon free acid; aurin tricarboxylic acid; Aluminon; MFCD00011663; UNII-NP9O8E29QW; NP9O8E29QW; 5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid); MLS002153482; SMR000326731; NSC643698; SR-01000075661; NSC 4056; EINECS 224-628-1; BRN 2228904; Dupont ATA; Lopac-A-1895; chrome violet CG free acid; AURINTRICARBOXYLICACID; cid_2259; Lopac0_000054; SCHEMBL98495; 4-10-00-04161 (Beilstein Handbook Reference); SPECTRUM1505163; CHEMBL275938; DTXSID9063453; BDBM60996; CTK7I5976; HMS3260K09; KS-00000US4; ZINC3833863; Tox21_500054; SBB005410; AKOS015969706; CCG-204149; LP00054; MCULE-4200379590; SDCCGSBI-0050042.P002; Dupont DA 639 (SD-095345); NCGC00015040-01; NCGC00015040-02; NCGC00015040-03; NCGC00015040-04; NCGC00015040-05; NCGC00015040-06; NCGC00015040-08; NCGC00093568-01; NCGC00096052-01; NCGC00096052-02; NCGC00260739-01; SC-88716; ST057219; HY-122575; CS-0087159; EU-0100054; FT-0622509; A 1895; Q4822390; SR-01000075661-1; SR-01000075661-7; Aurintricarboxylic acid, practical grade, >=85% (titration), powder
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| Activity |
IC50 = 53000 nM
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[4] | |||
| Compound Name |
[(2,5-Dichlorophenyl)carbamoyl]methyl 2-aminobenzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL559770; ZINC6392576; BDBM50295157
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| Activity |
IC50 = 58000 nM
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[8] | |||
| Compound Name |
2-Oxo-2-(5-phenyl-1,3,4-oxadiazol-2-ylamino)ethyl 3-phenoxybenzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL567356; BDBM50303389
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
4-(Pyrrolidin-1-ylsulfonyl)-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL567337; SMR000060788; MLS000054451; Oprea1_397193; MLS002637142; HMS2482B09; ZINC3204843; BDBM50303388; AKOS001026641; CCG-193388; MCULE-3498230309; Z28307393; F0012-0212; 4-(pyrrolidin-1-ylsulfonyl)-N-[4-(2-thienyl)-1,3-thiazol-2-yl]benzamide; 4-(pyrrolidine-1-sulfonyl)-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]benzamide
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
Methyl 4-[3-(5-bromo-2-furyl)-1,2,4-oxadiazol-5-yl]benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL567735; methyl 4-[3-(5-bromofuran-2-yl)-1,2,4-oxadiazol-5-yl]benzoate; methyl 4-(3-(5-bromofuran-2-yl)-1,2,4-oxadiazol-5-yl)benzoate; MLS000119208; HMS2251D16; ZINC116787; BDBM50303397; STK774168; AKOS001730458; MCULE-3080158905; SMR000096136; ST084018
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
2-(2-(4-Methyl-4H-1,2,4-triazol-3-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL571296; SMR000065003; MLS000098416; MLS002633483; cid_2514971; HMS2485O21; KUC113431N; ZINC3396507; BDBM50303406; AKOS033712325; MCULE-3792958208; YTL-373-001-3; MLS-0031359.0001; MLS-0031359.0002; SR-01000075035; SR-01000075035-1; Z19813136
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
2-Nitro-N-[[4-[(1,2,3,4-tetrahydronaphthalen-2-ylmethylamino)methyl]cyclohexyl]methyl]benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL299879; BDBM50114974; BRD-A94413429-003-01-6; Q27163767
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| Activity |
IC50 ~ 60000 nM
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[2] | |||
| Compound Name |
[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]acetonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL570844; MLS000114241; Oprea1_138219; Oprea1_736471; cid_1633306; HMS2266B03; ZINC1896423; BDBM50303403; EiM07-28228; STL352440; AKOS000183962; MCULE-2737110353; SMR000091661; ST50101486; 2-(4-methyl-2-oxochromen-7-yloxy)ethanenitrile; 2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetonitrile; 2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetonitrile
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||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
2-[[4-(4-Fluorophenyl)-1,2-thiazol-2-ium-2-yl]sulfanyl]-N-(furan-2-ylmethylcarbamoyl)acetamide;chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566690
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[2] | |||
| Compound Name |
2-(4-Chlorobenzylthio)-1-(furan-2-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL578136; SMR000062223; MLS000098321; HMS2276F05; ZINC3265502; BDBM50303408; AKOS033620426; MCULE-2420697336; Z18433342; 2-{[(4-chlorophenyl)methyl]sulfanyl}-1-(furan-2-yl)ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
2-(5-Methylisoxazol-3-ylamino)-2-oxoethyl 2-methyl-5-(N-m-tolylsulfamoyl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL567323; SMR000063496; MLS000081812; MLS001332849; HMS2386C20; ZINC2654246; BDBM50303395; AKOS033649423; MCULE-5302260312; Z18914193
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
5-Bromo-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-thiophenecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL576039; SMR000080590; MLS000051725; MLS002547920; HMS2437C21; ZINC1055160; BDBM50303386; STK463347; AKOS003352459; MCULE-5599862488; ST50938987; SR-01000292115; SR-01000292115-1; (5-bromo(2-thienyl))-N-(5-ethylthio(1,3,4-thiadiazol-2-yl))carboxamide; 5-bromo-N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)thiophene-2-carboxamide; 5-bromo-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]thiophene-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
S-2-(3-Chloro-4-methylphenylamino)-2-oxoethyl carbamothioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566933; SMR000104228; CBMicro_010697; MLS000108267; cid_873495; REGID_for_CID_873495; SCHEMBL12127479; HMS2176E11; ZINC441313; SMSF0010555; BDBM50303399; STL363763; AKOS000352143; CB13696; MCULE-2001823095; BIM-0010563.P001; AB00101626-01; SR-01000224197; SR-01000224197-1; S-{2-[(3-chloro-4-methylphenyl)amino]-2-oxoethyl} carbamothioate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
1-Phenyl-4-{[(5-phenyl-1,3,4-oxadiazol-2-yl)thio]acetyl}piperazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566706; SMR000077375; 2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)-1-(4-phenylpiperazin-1-yl)ethanone; MLS000064654; MLS002546791; HMS2451G15; ZINC2720269; BDBM50303394; STK138134; AKOS000364358; MCULE-3067799417; 2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-(4-phenylpiperazin-1-yl)ethanone; F0594-0007; 2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)-1-(4-phenylpiperazin-1-yl)ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-1,2-oxazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMR000063580; MLS000081820; N-(4-(p-tolyl)thiazol-2-yl)isoxazole-5-carboxamide; N-[4-(p-tolyl)thiazol-2-yl]isoxazole-5-carboxamide; CHEMBL577758; SCHEMBL22728453; BDBM35377; cid_2999703; HMS2364O22; ZINC4144714; AKOS024471412; MCULE-6925804121; Z27853449; F2833-0031; N-[4-(4-methylphenyl)-2-thiazolyl]-5-isoxazolecarboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
S-2-(3-Chlorophenylamino)-2-oxoethyl carbamothioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL577546; CBMicro_008686; MLS000108274; REGID_for_CID_873501; SCHEMBL12127504; HMS2182O03; ZINC441325; SMSF0010583; BDBM50303400; AKOS000348381; MCULE-2553726251; SMR000104235; BIM-0008752.P001; SR-01000224221; SR-01000224221-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
2,4-Dimethoxy-N-(1,3,4-thiadiazol-2-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL568419; SMR000091665; Oprea1_539392; MLS000114245; 2,4-Dimethoxy-N-[1,3,4]thiadiazol-2-yl-benzamide; HMS2263A16; ZINC338636; BDBM50303404; STK117323; AKOS000650128; MCULE-3981540953; ST50015244; AA-504/33804015; Z62439098; (2,4-dimethoxyphenyl)-N-(1,3,4-thiadiazol-2-yl)carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
2-[3-(Phenylcarbonyl)-1H-indol-1-yl]-1-(pyrrolidin-1-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL568420; MLS000115404; HMS2239G03; HMS3366N10; ZINC573681; BDBM50303405; STK136839; AKOS000471782; MCULE-8911586889; SMR000092516; ST50026503; 2-[3-(phenylcarbonyl)indolyl]-1-pyrrolidinylethan-1-one; 2-(3-benzoyl-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
N-{4-[4-(1-Azepanylsulfonyl)phenyl]-1,3-thiazol-2-yl}-2-thiophenecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566064; SMR000071413; Oprea1_088376; Oprea1_390714; MLS000099777; MLS000910880; SCHEMBL17073122; cid_1161245; HMS2359H14; ZINC8914268; BDBM50303385; STK798454; STK854960; AKOS000529960; AKOS005631272; MCULE-7251211916; SR-01000500112; SR-01000500112-1; Z57219895; N-(4-(4-(azepan-1-ylsulfonyl)phenyl)thiazol-2-yl)thiophene-2-carboxamide; N-{4-[4-(azepan-1-ylsulfonyl)phenyl]-1,3-thiazol-2-yl}thiophene-2-carboxamide; N-{4-[4-(azepane-1-sulfonyl)phenyl]-1,3-thiazol-2-yl}thiophene-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
N-(5-Methyl-1,2-oxazol-3-yl)-2-thiophen-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS-0024020.0001; N-(5-methyl-3-isoxazolyl)-2-(2-thienyl)acetamide; N-(5-methylisoxazol-3-yl)-2-(2-thienyl)acetamide; Oprea1_038047; MLS000062277; CHEMBL578585; cid_717599; SCHEMBL2117148; BDBM31765; HMS2383E10; ZINC116298; STK079842; AKOS000648564; CCG-110187; MCULE-9013071147; SDCCGMLS-0024020.P002; SMR000071090; EU-0009632; MLS000062277-02; ST50302703; N-(5-methyl-3-isoxazolyl)-2-thiophen-2-ylacetamide; N-(5-methyl-1,2-oxazol-3-yl)-2-(thiophen-2-yl)acetamide; N-(5-methyl-1,2-oxazol-3-yl)-2-thiophen-2-yl-ethanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
5-Isobutyl-N-(5-methylisoxazol-3-yl)isoxazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL565812; SMR000093385; MLS000116408; HMS2238G17; HMS3367O17; ZINC2498105; BDBM50303398; AKOS001797983; MCULE-3719869945; ST50675538; SR-01000104912; SR-01000104912-1; N-(5-methylisoxazol-3-yl)[5-(2-methylpropyl)isoxazol-3-yl]carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
3-(3-Chlorobenzo[b]thiophen-2-yl)-2-(1-methyl-1H-benzo[d]imidazol-2-yl)-3-oxopropanenitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL567529; Oprea1_715859; MLS000081882; cid_2998581; HMS2476O12; BDBM50303390; STL581120; AKOS001015035; AKOS016876794; MCULE-5805555099; SMR000060528
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
N-(3-Hydroxy-4,5-diphenylfuran-2-yl)-2-(2-oxobenzo[d]oxazol-3(2H)-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL567335; BDBM50303387
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
(2,3-Dimethoxyphenyl)(1-ethyl-1H-imidazol-2-yl)methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566707; MLS000114196; CBMicro_041184; Oprea1_024626; Oprea1_095617; (2,3-Dimethoxy-phenyl)-(1-ethyl-1H-imidazol-2-yl)-methanol; HMS2255G20; BDBM50303402; STK038160; AKOS000673652; AKOS017396767; MCULE-3334052934; NCGC00085613-02; SMR000091627; BIM-0041233.P001; AB00435205-09
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
3-Amino-4''-methyl-5-(2-methylallylthio)biphenyl-2,6-dicarbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566932; BDBM50303383
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
{[(2H-1,3-Benzodioxol-5-yl)methyl]carbamoyl}methyl 2-(furan-2-yl)quinoline-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL567531; SMR000061058; MLS000081948; Oprea1_290163; MLS001332706; cid_2368254; HMS2161M24; HMS3317M22; ZINC3251243; BDBM50303396; AKOS033643340; CCG-276426; MCULE-5300899364; BRD-K11018139-001-08-1; Z18798950
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[2] | |||
| Compound Name |
2-[(7-Chloroquinolin-4-yl)amino]ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7-Chloro-4-(2-hydroxyethyl)aminoquinoline; CHEMBL31000; 2-(7-CHLOROQUINOLIN-4-YLAMINO)ETHANOL; 2-((7-Chloroquinolin-4-yl)amino)ethanol; Oprea1_788408; SCHEMBL1855080; CTK5G8896; DTXSID80405251; ZINC2167250; BDBM50233287; AKOS008923002; MCULE-7038919277; 2-[(7-chloro-4-quinolyl)amino]ethanol; 2-[(7-chloro-4-quinolinyl)amino]ethanol; 4-(2-Hydroxyethylamino)-7-chloroquinoline; S-(+)-2,2-Dimethylcyclopropanecarboxamide; 7-chloro-4-(beta-hydroxyethylamino)quinoline; FT-0718552; 7-chloro-N-(2-hydroxyethyl)-4-quinolinamine; Ethanol, 2-[(7-chloro-4-quinolinyl)amino]-; 7-CHLORO-4-(2-HYDROXYETHYLAMINO)QUINOLINE; AI-204/31700046
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[10] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563197; BDBM50295122; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(4-morpholin-4-yl-phenyl)-amide
Click to Show/Hide
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||||
| Activity |
IC50 = 62000 nM
|
[8] | |||
| Compound Name |
N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-(2-cyanophenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233084; SCHEMBL13406077; BDBM50007620; AKOS008296574
Click to Show/Hide
|
||||
| Activity |
IC50 = 65100 nM
|
[11] | |||
| Compound Name |
2-[(Benzofuroxan-5-yl)methylene]-1-(2-hydroxybenzylidene)hydrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL444202; BDBM50243052
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[12] | |||
| Compound Name |
Pyridin-3-yl 2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL406555; SMR000082132; MLS000066727; HMS2304P22; BDBM50373132; STK847821; ZINC37867299; 3-pyridyl 2-oxochromene-3-carboxylate; AKOS002235555; MCULE-9637802138; ST50115107; 3-pyridinyl 2-oxo-2H-chromene-3-carboxylate; VU0178848-4; F3055-0142
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[4] | |||
| Compound Name |
Ethyl [(4E)-4-[[4-(dimethylamino)phenyl]methylidene]-5-oxo-1,3-thiazol-2-yl]sulfanylformate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL265957; BDBM50373129
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[4] | |||
| Compound Name |
4,6-Dichloro-3-hydroxy-3-[2-(2-hydroxyphenyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL259139; MLS000040513; HMS2161I18; HMS3315C10; BDBM50373127; STL360771; AKOS015954263; MCULE-2554140085; SMR000045242
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[4] | |||
| Compound Name |
2-[(Benzofuroxan-5-yl)methylene]-1-(5-bromo-2-hydroxybenzylidene)hydrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL470290; BDBM50243054
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[12] | |||
| Compound Name |
(E)-3-(1,3-Benzodioxol-5-yl)-N-[(E)-(2-hydroxyphenyl)methylideneamino]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2042788; BDBM50386186
Click to Show/Hide
|
||||
| Activity |
IC50 = 74800 nM
|
[9] | |||
| Compound Name |
2-(2,5-Dichlorophenylamino)-2-oxoethyl 2-aminonicotinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL541696; BDBM50295154; ZINC25157059; AKOS033614916; MCULE-9209314468; AB00714752-01; SR-01000036546; SR-01000036546-1; Z18385545; [(2,5-dichlorophenyl)carbamoyl]methyl 2-aminopyridine-3-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[8] | |||
| Compound Name |
(2S)-2-Amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SDZ 220-040; CHEMBL409024; NCGC00025080-01; Tocris-1251; SCHEMBL1998462; HMS3267H17; HMS3412C10; HMS3676C10; ZINC2581411; BDBM50373122; MFCD02262130; AKOS024456491; SDZ-220-040; SR-01000597391; J-011012; SR-01000597391-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[4] | |||
| Compound Name |
N-[2-(1H-Benzimidazol-2-yl)ethyl]-3-(2-bromophenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233096; BDBM50007631; AKOS008730881; NCGC00241725-01
Click to Show/Hide
|
||||
| Activity |
IC50 = 77500 nM
|
[11] | |||
| Compound Name |
N4-Phenyl benzofuroxan-5-carboxaldehydethiosemicarbazone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460050; BDBM50242827
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[12] | |||
| Compound Name |
1-(2,5-Dimethyl-benzyl)-5-methyl-1H-indole-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL118638; BDBM50133621; AKOS010743006; 1-(2,5-dimethylbenzyl)-5-methyl-1h-indole-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[5] | |||
| Compound Name |
1-(Benzyloxycarbonyl)-5-chloro-2,3-dihydro-1H-indole-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL326185; BDBM50133633; benzyl 5-chloro-2,3-dioxoindoline-1-carboxylate; 5-Chloro-2,3-dioxo-2,3-dihydro-indole-1-carboxylic acid benzyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[5] | |||
| Compound Name |
Chembl4161560
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL563046; BDBM50282194; 1,5-dibenzyl-2,2-dioxo-6-phenylimidazo[4,5-c][1,2,6]thiadiazin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[13] | |||
| Compound Name |
5-(2-Aminophenyl)-N-[(2-morpholin-4-ylpyridin-4-yl)methyl]-1,3,4-oxadiazole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL565191; BDBM50295116; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(2-morpholin-4-yl-pyridin-4-ylmethyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[8] | |||
| Compound Name |
(E)-3-(3,4-Dimethoxy-5-nitrophenyl)-N-[(E)-(2-hydroxyphenyl)methylideneamino]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2042792; BDBM50386180
Click to Show/Hide
|
||||
| Activity |
IC50 = 83900 nM
|
[9] | |||
| Compound Name |
2-(1-(4-Bromophenyl)propylamino)-2-oxoethyl 2-aminonicotinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562106; BDBM50295158
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[8] | |||
| Compound Name |
Ethyl (2Z)-2-[(3-ethoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)imino]-4-methyl-3-prop-2-enyl-1,3-thiazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827174; BDBM50187496
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[7] | |||
| Compound Name |
Chembl4176677
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL563011; BDBM50282193; 1-[(4-chlorophenyl)methyl]-6-(2-fluorophenyl)-2,2-dioxo-5H-imidazo[4,5-c][1,2,6]thiadiazin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[13] | |||
| Compound Name |
[(3-Carbamoylthiophen-2-yl)carbamoyl]methyl 2-amino-5-bromobenzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL554709; ZINC4246232; BDBM50295124; AKOS033447986; MCULE-9150937120; AB00765917-01; Z15885695; 2-(3-carbamoylthiophen-2-ylamino)-2-oxoethyl 2-amino-5-bromobenzoate
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[8] | |||
| Compound Name |
1-Benzyl-5-chloro-1H-indole-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336693; 1-benzyl-5-chloroindoline-2,3-dione; 1-benzyl-5-chloro-2,3-dihydro-1H-indole-2,3-dione; 1-benzyl-5-chloroindole-2,3-dione; SCHEMBL16798714; ZINC2482985; BBL015389; BDBM50133625; MFCD02315132; STK394567; AKOS000245878; CCG-279619; MCULE-5172131128; 5-chloro-1-benzylbenzo[d]azoline-2,3-dione; EU-0047901; ST50879467; SR-01000111906; SR-01000111906-1; Z57175680
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| Activity |
IC50 = 90000 nM
|
[5] | |||
| Compound Name |
1-Benzyl-5-iodoindoline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL118596; 1-Benzyl-5-iodo-1H-indole-2,3-dione; SCHEMBL5114805; 1-benzyl-5-iodoindole-2,3-dione; BDBM50133617; ZINC13553659; 1-benzyl-5-iodo-indoline-2,3-dione; 5-iodo-1-benzyl-1H-indole-2,3-dione; DA-29734; FT-0721819; 1H-Indole-2,3-dione, 5-iodo-1-(phenylmethyl)-
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||||
| Activity |
IC50 = 90000 nM
|
[5] | |||
| Compound Name |
N-[2-[5-[(2,4-Dichlorophenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamic acid tert-butyl ester
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Investigative | Compound Info | ||
| Synonyms |
MLS000041932; ML025; SMR000046713; MLS002583822; CHEMBL259018; cid_665449; BDBM66247; HMS2273E06; ZINC2419575; STL348854; AKOS022098623; MCULE-8830819999; Q27164169
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||||
| Activity |
IC50 = 95000 nM
|
[4] | |||
| Compound Name |
(1S,2R,3R,4R,7S)-7-Methyl-3-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL261208
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||||
| Activity |
IC50 = 95000 nM
|
[4] | |||
| Compound Name |
Tert-butyl N-[[5-[(2,4-dichlorophenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]methyl]carbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL261812; BDBM50373121
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||||
| Activity |
IC50 = 95000 nM
|
[4] | |||
| Compound Name |
Vitamin E Nicotinate
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Investigative | Compound Info | ||
| Synonyms |
tocopherol nicotinate; TOCOPHERYL NICOTINATE; Renascin; DL-alpha tocopheryl nicotinate; UNII-WI1J5UCY5C; (+/-)-alpha-Tocopherol nicotinate; D-alpha tocopheryl nicotinate; DL-alpha-Tocopheryl Nicotinate; WI1J5UCY5C; dl-alpha-Tocopherol nicotinate; CHEMBL1084541; NCGC00164499-01; NCGC00164499-03; DSSTox_CID_26396; DSSTox_RID_81576; DSSTox_GSID_46396; Kentons; Vitamin E nicotinic acid ester; EINECS 256-101-7; alpha-tocopherol nicotinate; BRN 0466142; Tocopherol nicotinate [JAN]; MFCD03548047; alpha-Tocopherol nicotinate, DL-; EINECS 257-501-4; Juvela nicotinate (TN); Alpha-tocopheryl nicotinate; Alpha-Tocophenyl nicotinate; alpha-toco-pherol nicotinate; A-Tocopherol nicotinate; SCHEMBL42668; Tocopherol nicotinate (JP17); 5-Methylpyridine-2-boronicacid; DTXSID1046396; CTK8B8715; DTXSID401019802; ZINC4654831; Tox21_112137; ANW-61107; BDBM50318914; SBB058193; AKOS015896058; Tox21_112137_1; AC-6859; AM90301; VITAMIN E NICOTINATE, 97.0%; NCGC00164499-02; AS-15224; SC-19232; SC-20324; ST51015145; C12981; D01530; 676V758; SR-01000944628; SR-01000944628-2; W-105861; Q27114834; UNII-QCP2FMP7I8 component MSCCTZZBYHQMQJ-AZAGJHQNSA-N
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||||
| Activity |
IC50 = 98000 nM
|
[1] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(3-pyrrolidin-1-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL559646; BDBM50295107; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(3-pyrrolidin-1-yl-phenyl)-amide
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||||
| Activity |
IC50 = 99000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-piperidin-4-yl-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL561845; BDBM50295101; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid piperidin-4-ylamide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N4-Allyl benzofuroxan-5-carboxaldehydethiosemicarbazone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL460049; BDBM50242826; 4-Allyl-1-(N1-oxide-benzo[1,2-c][1,2,5]oxadiazole-5-yl)-methylidenethiosemicarbazide
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||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(2-morpholin-4-ylethyl)-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL554556; BDBM50295112; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(2-morpholin-4-yl-ethyl)-amide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-[(3S)-2-oxoazepan-3-yl]-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL561769; BDBM50295150; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(2-oxo-azepan-3-yl)-amide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
4-(Benzofuroxan-5-ylmethyloxy)benzaldehydesemicarbazone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL459639; BDBM50242830
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||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(2-methylpyrazol-3-yl)-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL563815; BDBM50295120; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(2-methyl-2H-pyrazol-3-yl)-amide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(2-methyl-1H-indol-5-yl)-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL555241; BDBM50295105; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(2-methyl-1H-indol-5-yl)-amide
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
1-Benzoyl-1H-indole-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
N-Benzoylisatin; CHEMBL118830; 1H-Indole-2,3-dione, 1-benzoyl- (9CI); UNII-276X936194; 1-Benzoylisatin; 276X936194; 1-benzoylindole-2,3-dione; 1-Benzoyl-indole-2,3-dione; NSC 127078; BRN 0016540; NSC127078; INDOLE-2,3-DIONE, 1-BENZOYL-; SCHEMBL10353187; CTK4G1157; DTXSID60182533; 1H-Indole-2,3-dione,1-benzoyl-; ZINC1715655; BDBM50133616; STK051154; AKOS000618468; NSC-127078; 1-(phenylcarbonyl)-1H-indole-2,3-dione; SR-01000321021; SR-01000321021-1
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||||
| Activity |
IC50 = 100000 nM
|
[5] | |||
| Compound Name |
2-[(Benzofuroxan-5-yl)methylene]-1-(4-hydroxybenzylidene)hydrazine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL504491; BDBM50243053
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||||
| Activity |
IC50 = 100000 nM
|
[12] | |||
| Compound Name |
Benzofuroxan-5-carboxaldehyde thiosemicarbazone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL460048; BDBM50242825
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(1-methylpyrazol-3-yl)-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL549410; BDBM50295114; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(1-methyl-1H-pyrazol-3-yl)-amide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-[2-(2-oxoimidazolidin-1-yl)ethyl]-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL563851; BDBM50295151; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid[2-(2-oxo-imidazolidin-1-yl)-ethyl]-amide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N'-[(E)-(2-Hydroxyphenyl)methylidene]-3-phenylpropanehydrazide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2042797; BDBM50386182; STK730880; ZINC95935796; AKOS001596260; ST055947; N'-(2-hydroxybenzylidene)-3-phenylpropanohydrazide; SR-01000080191; SR-01000080191-1; N'-[(1E)-(2-hydroxyphenyl)methylene]-3-phenylpropanohydrazide; N-[(1E)-2-(2-hydroxyphenyl)-1-azavinyl]-3-phenylpropanamide
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid 3,4,5-trimethoxybenzylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL564049; BDBM50295153
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(((S)-1-ethylpyrrolidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL556464; BDBM50295111
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-[3-(2-oxopyrrolidin-1-yl)propyl]-1,3,4-oxadiazole-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL552098; BDBM50295113; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid [3-(2-oxo-pyrrolidin-1-yl)-propyl]-amide
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(1S,2S)-2-(4-Chlorobenzoyl)-N-((S,E)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)cyclohexanecarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1079105; BDBM50311253
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||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(3-imidazol-1-ylpropyl)-1,3,4-oxadiazole-2-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL562782; BDBM50295102; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(3-imidazol-1-yl-propyl)-amide
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-(2-Aminophenyl)-N-(5-thiophen-2-yl-1H-pyrazol-3-yl)-1,3,4-oxadiazole-2-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL560043; BDBM50295104; 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(5-thiophen-2-yl-1Hpyrazol-3-yl)-amide
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| Activity |
IC50 = 102000 nM
|
[8] | |||
| Compound Name |
Benzotriazol-1-yl-(2-methylfuran-3-yl)methanone
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Investigative | Compound Info | ||
| Synonyms |
SMR000072033; MLS000066844; 1-(2-methyl-3-furoyl)-1H-1,2,3-benzotriazole; CHEMBL437061; cid_898637; BDBM33434; HMS2416L15; ZINC476593; STK440954; AKOS003296386; MCULE-3825843278; benzotriazolyl 2-methyl(3-furyl) ketone; ST50829360; 1-benzotriazolyl-(2-methyl-3-furanyl)methanone; benzotriazol-1-yl-(2-methyl-3-furyl)methanone; SR-01000257399; 1H-benzotriazol-1-yl(2-methylfuran-3-yl)methanone; SR-01000257399-1
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| Activity |
IC50 = 106000 nM
|
[4] | |||
| Compound Name |
8-Methoxy-3-[(3-methylpyrazolyl)carbonyl]chromen-2-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL408636; SMR000079121; MLS000065365; HMS2285L06; ZINC615863; BDBM50373126; AKOS001263349; MCULE-8698208469; ST50169339; SR-01000286266; SR-01000286266-1; F1732-0040; 8-methoxy-3-(3-methyl-1H-pyrazole-1-carbonyl)-2H-chromen-2-one; 8-methoxy-3-[(3-methyl-1H-pyrazol-1-yl)carbonyl]-2H-chromen-2-one
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| Activity |
IC50 = 106000 nM
|
[4] | |||
| Compound Name |
2-[(2Z)-4-Oxo-2-[(3-propan-2-yloxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)imino]-3-prop-2-enyl-1,3-thiazolidin-5-yl]acetic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827125; BDBM50187499
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|
||||
| Activity |
IC50 = 111000 nM
|
[7] | |||
| Compound Name |
2-(2-{[3-(Ethoxycarbonyl)(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)]azamethylen e}-4-oxo-3-phenyl-1,3-thiazolidin-5-yl)acetic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3827864; BDBM50187497; AKOS024380574; ST51026625
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||||
| Activity |
IC50 = 121000 nM
|
[7] | |||
| Compound Name |
Delavirdine mesylate
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Investigative | Compound Info | ||
| Synonyms |
Delavirdine (mesylate); Delavirdine mesilate; Rescriptor; U-90152S; UNII-421105KRQE; Delavirdine monomethanesulfonate; delavirdine methanesulfonate; Delavirdine mesylate [USAN]; 421105KRQE; Delavirdine mesylate (USAN); U 90152 (mesylate);BHAP-U 90152 (mesylate); SR-05000001471; Rescriptor (TN); CHEMBL929; Delavirdine mesilate (JAN); SCHEMBL40522; DTXSID701017136; BCP09460; 3575AH; HY-10571A; MFCD00866948; s6452; AKOS024458004; CS-1661; Delavirdine mesylate, >=98% (HPLC); BS-15144; U-90152T; FT-0603116; C08087; D00895; J-008332; SR-05000001471-2; Q27068164
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| Activity |
IC50 = 122000 nM
|
[1] | |||
| Compound Name |
Chembl4213366
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Investigative | Compound Info | ||
| Synonyms |
BDBM50451633
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| Activity |
Ki = 125892.54 nM
|
[15] | |||
| Compound Name |
2-(2-(Difluoromethoxy)phenylamino)-2-oxoethyl 2-aminonicotinate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL549615; BDBM50295125; ZINC25539935; AKOS033614817; MCULE-4564615669; AB00738757-01; SR-01000073689; SR-01000073689-1; Z18384673; {[2-(difluoromethoxy)phenyl]carbamoyl}methyl 2-aminopyridine-3-carboxylate
Click to Show/Hide
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||||
| Activity |
IC50 = 126000 nM
|
[8] | |||
| Compound Name |
Meclizine hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
Meclozine hydrochloride; Meclizine Monohydrochloride; Duremesin; MLS000028709; CHEMBL1085765; Vertizine; Taizer; SMR000058736; V-Cline; Ancolan dihydrochloride; Postafene dihydrochloride; 1-((4-Chlorophenyl)benzyl)-4-((m-tolyl)methyl)piperazine hydrochloride; Meclozine monohydrochloride; 1-[(4-chlorophenyl)benzyl]-4-[(m-tolyl)methyl]piperazine hydrochloride; EINECS 252-932-4; Meclizine monohydrochloride anhydrous; CPD000058736; Opera_ID_1833; SCHEMBL41366; MLS002222222; Parachloramine, dihydrochloride; CTK8I4194; DTXSID80957624; Pharmakon1600-01500376; NSC28728; NSC-28728; NSC757094; SBB058162; 1-(p-Chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)piperazine hydrochloride; AKOS024374956; MCULE-4211025798; NC00640; NSC-757094; Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)-, hydrochloride; NCGC00180908-01; NCGC00180908-02; MECLIZINE HYDROCHLORIDE (500 MG); ST51015044; VU0239821-5; 569M653; WLN: T6N DNTJ AYR&R DG& D1R C1 &GH 2; Q27231341; 1-p-Chlorbenzhydryl-(m-methylbenzyl)piperazine dihydrochloride; Meclozine dihydrochloride, European Pharmacopoeia (EP) Reference Standard
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||||
| Activity |
IC50 = 129000 nM
|
[1] | |||
| Compound Name |
Candesartan cilexetil
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Investigative | Compound Info | ||
| Synonyms |
Atacand; TCV-116; Amias; Parapres; Kenzen; candesartancilexetil; CANDESARTAN CILEXTIL; TCV 116; C33H34N6O6; CHEMBL1014; TCY 116; MFCD00871371; Candesartan cilexetil [USAN]; Racanda; Candesartan hexetil; Atacand (TN); candesartan cilexitil; Spectrum_001707; Candesartan (Cilexetil); DSSTox_CID_239; Spectrum2_000485; Spectrum3_000996; Spectrum4_001124; Spectrum5_001462; DSSTox_RID_85567; DSSTox_GSID_20239; SCHEMBL40831; BSPBio_002691; KBioGR_001607; KBioSS_002187; MLS004774127; Candesartan cilexetil , 97%; SPECTRUM1504261; SPBio_000349; GTPL8352; Candesartan cilexetil (Atacand); DTXSID5020239; KBio2_002187; KBio2_004755; KBio2_007323; KBio3_001911; KS-00000IVU; EBD4212; HMS1922J09; HMS2093E20; HMS3651I08; Pharmakon1600-01504261; Candesartan cilexetil (JP17/USP); BCP22050; Tox21_302202; AC-204; BDBM50318907; CCG-39530; NSC758697; s2037; STL451065; AKOS015894954; AKOS015920180; AB07617; AM90293; BCP9000480; CCG-222334; DB00796; DS-1302; KS-1147; NSC-758697; VA10473; Candesartan cilexetil, >=98% (HPLC); NCGC00095123-01; NCGC00095123-02; NCGC00095123-03; NCGC00095123-05; NCGC00095123-10; NCGC00095123-16; NCGC00255218-01; AK-75900; BR-75900; HY-17505; SC-12740; SMR003500784; SBI-0206767.P001; AB0012012; C-265; FT-0602914; SW220041-1; A-2005; C07709; D00626; J10436; AB01274805-01; AB01274805_02; AB01274805_03; 040C375; H212/91; L006257; SR-05000001976; Q-200786; SR-05000001976-1; BRD-A65671304-001-02-6; BRD-A65671304-001-03-4; Q27075664
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||||
| Activity |
IC50 = 168000 nM
|
[1] | |||
| Compound Name |
2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylamino)-2-oxoethyl 2-aminonicotinate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL563022; BDBM50295126; ZINC25685889; AKOS033614791; MCULE-5296393279; Z18384482; [(2,3-dihydro-1,4-benzodioxin-6-yl)carbamoyl]methyl 2-aminopyridine-3-carboxylate
Click to Show/Hide
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||||
| Activity |
IC50 = 182000 nM
|
[8] | |||
| Compound Name |
Chlorpromazine hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
Chlorpromazine Hcl; Sonazine; Chloractil; Klorpromex; Promacid; Hebanil; Propaphenin; Hybernal; Klorproman; Lomazine; Neurazine; Norcozine; Plegomazin; Promachel; Promexin; Taroctyl; Tranzine; Hibernal; Promapar; Unitensen; Chlorpromazine (hydrochloride); Aminazin monohydrochloride; Fenactil monohydrochloride; Chloropromazine monohydrochloride; Ampliactil monohydrochloride; Hibanil; Chlorpromazinium chloride; Chlorpromazine monohydrochloride; NCI-C05210; CHLOROPROMAZINE HYDROCHLORIDE; Chlorpromazine, Hydrochloride; Propaphen; UNII-9WP59609J6; Thorazine hydrochloride; MLS000069401; MFCD00012654; NSC-17479; 9WP59609J6; 69-09-0 (HCl); Aminazinum; Megatil; SMR000058254; 4560 Rp hydrochloride; Contomin hydrochloride; Megaphen hydrochloride; Phenothiazine hydrochloride; Largactil monohydrochloride; CPZ (VAN); NSC17479; CCRIS 6221; NSC-226514; SR-01000000012; EINECS 200-701-3; NSC 17479; Chloropromazin hydrochloride; Largaktyl; AI3-28023; Prestwick_58; Sonazine (TN); Chlorpromazine Hydrochloride Intensol; Chlorpromazine chloride; AC1LCWF1; Chlorpromazine hydrochloride [USP:BAN:JAN]; Opera_ID_1294; C17H19ClN2S.HCl; DSSTox_CID_4827; CHEMBL1713; DSSTox_RID_77545; DSSTox_GSID_24827; SCHEMBL41771; MLS001148603; MLS002222157; ARONIS23911; Chlorpromazin-d6 hydrochloride; ChlorpromazineHydrochloride,98%; DTXSID7024827; CTK8B3386; HY-B0407A; Chlorpromazine hydrochloride, 98%; HMS1568M09; BCP30284; Tox21_300517; Tox21_500249; ANW-42443; NSC226514; s2456; SBB057793; AKOS005111082; CCG-220064; CCG-221553; LP00249; MCULE-8792081568; NC00552; KS-00000V46; 7-[Diethylamino]coumarin-3-carbonylazide; Chlorpromazine hydrochloride (JP17/USP); NCGC00024409-09; NCGC00093711-01; NCGC00093711-02; NCGC00180973-01; NCGC00254272-01; NCGC00260934-01; AC-10573; SC-18311; AB0013284; C-165; Chlorpromazine hydrochloride, >=98% (TLC); EU-0100249; FT-0623715; FT-0665009; ST50331291; SW196373-5; C 8138; C07952; Chlorpromazine, Hydrochloride - CAS 69-09-0; D00789; MLS-0090820.0001; WLN: T C666 BN ISJ B3N1&1 EG &GH; 012C654; Q-200842; SR-01000000012-2; SR-01000000012-9; Q27106159; Z1259155914
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||||
| Activity |
IC50 = 189000 nM
|
[1] | |||
| Compound Name |
Chembl4203721
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Investigative | Compound Info | ||
| Synonyms |
BDBM50451632
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|
||||
| Activity |
Ki = 199526.23 nM
|
[15] | |||
| Compound Name |
Click to Show/Hide
|
Compound Info | |||
| Activity |
IC50 = 88000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 30 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Etravirine
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Intelence; DAPY deriv; Diaminopyrimidine deriv; R 165335; R165335; TMC 125; TMC125; Intelence (TN); Intelence(TM); R-165335; R165335-TMC125; TMC-125; Etravirine (JAN/USAN/INN); TMC-125/R-165335; 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile; 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE; 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile; 65B; ETR
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|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
Imatinib
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|
Approved | Compound Info | ||
| Synonyms |
Cgp 57148; Glamox; Glamox (TN); Gleevec (TN); Glivec (TN); Imatinib (INN); Imatinib (STI571); Imatinib Methansulfonate; Imatinib [INN:BAN]; 112GI019; 152459-95-5; BKJ8M8G5HI; CCRIS 9076; CGP-57148; CHEMBL941; Imatinib free base; STI; UNII-BKJ8M8G5HI
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|
||||
| Activity |
IC50 = 207000 nM
|
[1] | |||
| Compound Name |
Sporanox
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|
Investigative | Compound Info | ||
| Synonyms |
itraconazole; Itraconazolum [Latin]; ITRAZOLE; Itraconazol; MLS000863291; R 51211; SMR000058959; R-51211; Itraconazole Impurity E; SR-01000003153; Itraconzaole; trans Itraconazole; R51211; Itraconazole,(S); NCGC00018268-03; Itraconazole solution; PubChem16053; Opera_ID_902; R 51,211; SCHEMBL95627; MLS000028582; MLS000759472; MLS001148245; MLS001424065; CHEMBL64391; Itraconazole, >=98% (TLC); SCHEMBL16984893; CTK6C9122; HMS2051K14; HMS2090M20; HMS2235M11; HMS3370P13; HMS3393K14; HMS3713B16; BCP28497; KS-00000JQ3; BDBM50011478; DL-427; MFCD00870168; STL450986; AKOS000280875; AKOS022171690; CCG-100876; CCG-220567; NC00126; NCGC00018268-02; NCGC00018268-06; NCGC00089812-03; AK133082; AB0068822; FT-0601621; FT-0670576; I0732; J10270; M-9651; AB00383031-14; 625I616; Itraconazole, Antibiotic for Culture Media Use Only; J-015921; Q-201261; SR-01000003153-5; SR-01000003153-6; Q27166205; Itraconazole, European Pharmacopoeia (EP) Reference Standard; Itraconazole, United States Pharmacopeia (USP) Reference Standard; Itraconazole, Pharmaceutical Secondary Standard; Certified Reference Material
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|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
Menatetrenone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
vitamin K2; Menaquinone-4; Menaquinone 4; Kefton-2; Vitamin MK 4; Kaytwo; Menaquinone K4; Menatetrenona; Menatetrenonum; 2-Methyl-3-trans-tetraprenyl-1,4-naphthoquinone; UNII-27Y876D139; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; C31H40O2; MLS000028742; MFCD00079646; SMR000058955; 27Y876D139; DSSTox_CID_28895; Vitamin K2(sub 20); Menatetrenone [INN:JAN]; Menatetrenonum [INN-Latin]; K2(sub 20); Menatetrenona [INN-Spanish]; Glakay; E3100; menaquinone(4); NCGC00183125-01; MENATETRANONE; MENSAQUINONE; Vitamin K2 (TN); Opera_ID_148; 2-Methyl-3-tetraprenyl-1,4-naphthoquinone; DSSTox_RID_80857; DSSTox_RID_83163; Menatetrenone (JP17/INN); DSSTox_GSID_45406; DSSTox_GSID_48969; MENAQUINONE;VITAMIN K2; SCHEMBL434553; SCHEMBL571912; Menaquinone 4; Vitamin K2 (MK-4) solution; CHEMBL259223; DTXSID6048969; HMS2230J06; Ea-0167; HY-B2156; ZINC3874199; Tox21_110567; Tox21_113413; BDBM50423776; s5082; AKOS025311021; Menaquinone (K2), analytical standard; CCG-269176; DB12148; NCGC00181325-01; NCGC00181325-03; AS-17910; AS-56161; SC-20542; SC-45486; CS-0020307; V2671; A17083; D00100; E-0167; 863V616; Q192354
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|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
[(2,5-Dichlorophenyl)carbamoyl]methyl 3-methylbenzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL570547; ZINC1943857; BDBM50295127; AKOS001319817; MCULE-8594297505; AB00762676-01; Z18750897; 2-(2,5-dichlorophenylamino)-2-oxoethyl 3-methylbenzoate
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||||
| Activity |
IC50 > 200000 nM
|
[8] | |||
| Compound Name |
2-(2,5-Dichlorophenylamino)-2-oxoethyl picolinate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563474; BAS 07224187; SMR000061477; Oprea1_192698; MLS000054092; HMS2182K24; ZINC807372; BDBM50295128; STL354304; AKOS000420049; MCULE-6717906609; ST50282817; AB00419990-05; Z19673344; [(2,5-dichlorophenyl)carbamoyl]methyl pyridine-2-carboxylate; [N-(2,5-dichlorophenyl)carbamoyl]methyl pyridine-2-carboxylate; 2-[(2,5-dichlorophenyl)amino]-2-oxoethyl pyridine-2-carboxylate
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|
||||
| Activity |
IC50 > 200000 nM
|
[8] | |||
| Compound Name |
Amiodarone hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
Amiodarone HCL; Nexterone; Amiodar; Uro-Septra; Amiodarone (hydrochloride); Pacerone; Amiodaronum hydrochloride; Atlansil; UNII-976728SY6Z; 51087 N HCl; MLS000028520; SKF 33134-A; MFCD00069204; NSC-85442; 976728SY6Z; SMR000058296; DSSTox_CID_17185; DSSTox_RID_79304; DSSTox_GSID_37185; L-3428; Ritmocardyl; Rythmarone; Angoron; Miodrone; Renodoron; Trangorex; L 3428 labaz; SR-01000003087; NCGC00015096-12; Ancaron; Amio-Aqueous; HSDB 6525; Cordarone (TN); Nexterone (TN); Prestwick_707; Amiodarone hydrochloride [USP:JAN]; Ancaron (TN); EINECS 243-293-2; SKF 33134 A; NSC 85442; AmiodaroneHydrochloride; CPD000058296; Opera_ID_568; C25H30ClI2NO3; SCHEMBL41348; MLS001076313; MLS001424272; MLS002222247; SPECTRUM2300165; Amiodarone hydrochloride [JAN]; Amiodarone hydrochloride solution; CHEMBL1083993; DTXSID7037185; calcium channel (L type) blocker; HMS1569A20; Pharmakon1600-02300165; ACT02681; Amiodarone Hydrochloride, >/=98%; BCP13645; NSC85442; SKF-33134-A; Ketone,5-diiodophenyl, hydrochloride; Tox21_113478; Tox21_300395; Tox21_500122; AC-078; CCG-39607; NSC759560; PM-101; s1979; SK&F-33134-A; Amiodarone hydrochloride (JP17/USP); AKOS015844018; CS-1371; KS-5249; LP00122; NC00423; NSC-759560; NCGC00093613-01; NCGC00093613-02; NCGC00093613-03; NCGC00093613-04; NCGC00254295-01; NCGC00260807-01; AK149490; HY-14188; Methanone,5-diiodophenyl]-, hydrochloride; AB0012080; EU-0100122; FT-0622300; SW196856-4; A 8423; D00636; W-5062; 774A824; Q-200626; SR-01000003087-2; SR-01000003087-8; WLN: T56 BOJ C4 DVR CI EI DO2N2&2 &GH; Q27271976; Z2210825534
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|
||||
| Activity |
IC50 = 206000 nM
|
[1] | |||
| Compound Name |
Chembl4208600
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50451626
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|
||||
| Activity |
Ki = 398107.17 nM
|
[15] | |||
| Compound Name |
{[(Benzylsulfonyl)amino]methyl}boronic Acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1231476; (benzylsulfonylamino)methylboronic acid; Pinacol(Phenylmethanesulfonylamino)Methaneboronate; SCHEMBL14861700; BDBM50330784; Q27458533
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[16] | |||
| Compound Name |
4-({[(Dihydroxyboranyl)methyl]sulfamoyl}methyl)benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1231477; [(4-Carboxyphenyl)Methanesulfonylamino]Methaneboronic Acid; SCHEMBL14861681; BDBM50330785; 4-(boronomethylsulfamoylmethyl)benzoic acid; Q27458535
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[16] | |||
| Compound Name |
Potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate
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|
Investigative | Compound Info | ||
| Synonyms |
D-609 potassium; D-609; SPK-601; potassium O-(octahydro-1H-4,7-methanoinden-5-yl) carbonodithioate; CHEMBL404954; O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate Potassium salt; tricyclodecane-9-yl-xanthogenate; D609, Potassium Salt; Tricyclodecan-9-yl xanthogenate potassium salt; MFCD00171401; D 609; Tricyclodecan-9-yl-xanthogenate, K; EINECS 280-379-9; UNII-5QC1Z07M77; 5QC1Z07M77; HMS1362A05; HMS3263J06; HMS3267J20; HMS3403A05; HMS3412B07; HMS3676B07; Tox21_501242; AKOS024456596; AKOS025147303; O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonodithioate potassium salt; CCG-207969; CCG-222546; CS-0078; LP01242; NCGC00016205-02; NCGC00025162-02; NCGC00094483-01; NCGC00261927-01; HY-70072; EU-0101242; T 8543; SR-01000597564; SR-01000597564-1; (Tricyclo[5.2.1.0~2,6~]Dec-8-Yloxy)Carbonothioylsulfide; O-(Octahydro-4,7-methano-1H-inden-5-yl) carbonopotassium dithioate; O-tricyclo[5.2.1.02,6] dec-9-yl dithiocarbonate potassium salt; potassium ({tricyclo[5.2.1.0?,?]decan-8-yloxy}methanethioyl)sulfanide; Carbonodithioic acid, O-(octahydro-4,7-methano-1H-inden-5-yl) ester potassium
Click to Show/Hide
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||||
| Activity |
IC50 > 600000 nM
|
[4] | |||
| Compound Name |
3,7-Bis(4-methoxybenzoyl)-1-methyl-5-propyl-3,7-diazabicyclo[3.3.1]nonan-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL261259; SMR000074052; MLS000096755; MLS000911032; HMS2169G07; HMS3311M13; ZINC1130323; BDBM50373130; STL520563; AKOS001520020; AKOS037492752
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|
||||
| Activity |
IC50 > 600000 nM
|
[4] | |||
| Compound Name |
2-(2,5-Dimethyl-pyrrol-1-yl)-3-phenyl-propionic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
2-(2,5-dimethylpyrrol-1-yl)-3-phenylpropanoic acid; MLS000072791; CHEMBL259355; SMR000010168; BAS 01191302; TimTec1_008209; cid_654761; SCHEMBL2115617; BDBM40576; CTK7I4650; HMS1557F03; BDBM50373133; AKOS000138607; AKOS017269117; MCULE-3646336452; ST50007660; MLS-0014214.0001; 2-(2,5-dimethylpyrrolyl)-3-phenylpropanoic acid; SR-01000317764; SR-01000317764-1; 2-(2,5-dimethyl-1-pyrrolyl)-3-phenylpropanoic acid; 2-(2,5-dimethylpyrrol-1-yl)-3-phenyl-propanoic acid; 2-(2,5-dimethylpyrrol-1-yl)-3-phenyl-propionic acid; BRD-A14745434-001-04-9; 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropanoic acid; 2-(2,5-dimethyl-1h-pyrrol-1-yl)-3-phenylpropionic acid; 2-(2,5-dimethyl-pyrrol-1-yl)-3-phenyl-propionic acid, AldrichCPR
Click to Show/Hide
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||||
| Activity |
IC50 > 600000 nM
|
[4] | |||
| Compound Name |
2-[1-Carboxy-2-(4-hydroxyphenyl)ethyl]-1,3-dioxoisoindoline-5-carboxylic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL258538; SMR000019628; MLS000085082; SCHEMBL21067955; HMS2410F13; BDBM50373131; EU-0013960; SR-01000083806; SR-01000083806-1
Click to Show/Hide
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||||
| Activity |
IC50 > 10000000 nM
|
[4] | |||
| Compound Name |
5-[(E)-[(3-Nitrobenzoyl)hydrazinylidene]methyl]furan-2-carboxylic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL37464; BDBM50421525
Click to Show/Hide
|
||||
| Activity |
IC50 = 3.02E+12 nM
|
[17] | |||
| Compound Name |
N-[(E)-Furan-3-ylmethylideneamino]-2,4-dimethoxybenzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL285167; BDBM50421521
Click to Show/Hide
|
||||
| Activity |
IC50 = 6.03E+12 nM
|
[17] | |||
| Compound Name |
2-Hydroxy-benzoic acid [5-(4-chloro-phenyl)-furan-2-ylmethylene]-hydrazide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL38462; 2-HYDROXY-BENZOIC ACID (5-(4-CHLORO-PHENYL)-FURAN-2-YLMETHYLENE)-HYDRAZIDE; BDBM50403913; STK215165; ZINC33281549; AKOS000523738; ST50226868; N'-{(E)-[5-(4-chlorophenyl)furan-2-yl]methylidene}-2-hydroxybenzohydrazide; N-{(1E)-2-[5-(4-chlorophenyl)(2-furyl)]-1-azavinyl}(2-hydroxyphenyl)carboxamid e
Click to Show/Hide
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||||
| Activity |
IC50 = 1.00E+13 nM
|
[17] | |||
| Compound Name |
N-[(E)-(4-Bromothiophen-2-yl)methylideneamino]quinoline-3-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL40503; BDBM50421532
Click to Show/Hide
|
||||
| Activity |
IC50 = 3.31E+13 nM
|
[17] | |||
| Compound Name |
2-Hydroxy-N'-[(E)-quinolin-4-ylmethylidene]benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289764; MLS001214333; BDBM50421529; STK593647; AKOS005515394; SMR000543819
Click to Show/Hide
|
||||
| Activity |
IC50 = 3.31E+13 nM
|
[17] | |||
| Compound Name |
2-Hydroxy-N'-{(E)-[5-(2-nitrophenyl)furan-2-yl]methylidene}benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289164; BDBM50421519; STK236311; ZINC33341018; 2-Hydroxy-benzoic acid [5-(2-nitro-phenyl)-furan-2-ylmethylene]-hydrazide; AKOS000523797
Click to Show/Hide
|
||||
| Activity |
IC50 = 5.01E+13 nM
|
[17] | |||
| Compound Name |
N-[(E)-[4-(Dimethylamino)naphthalen-1-yl]methylideneamino]-3,4-dihydroxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39723; BDBM50421527
Click to Show/Hide
|
||||
| Activity |
IC50 = 6.17E+13 nM
|
[17] | |||
| Compound Name |
5-[(E)-[(3,5-Dimethoxybenzoyl)hydrazinylidene]methyl]furan-2-carboxylic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL40119; BDBM50421523
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|
||||
| Activity |
IC50 = 1.00E+14 nM
|
[17] | |||
| Compound Name |
2-Hydroxy-3-methyl-N-[(E)-(5-methylsulfanylthiophen-2-yl)methylideneamino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40165; BDBM50421520
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|
||||
| Activity |
IC50 = 1.00E+14 nM
|
[17] | |||
| Compound Name |
3-Hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38981; SCHEMBL17988124; BDBM50421522; AKOS003850618
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.66E+14 nM
|
[17] | |||
| Compound Name |
N-[(E)-[5-(3-Nitrophenyl)furan-2-yl]methylideneamino]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39255; BDBM50421531
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.66E+14 nM
|
[17] | |||
| Compound Name |
N-[(E)-[4-(Dimethylamino)naphthalen-1-yl]methylideneamino]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289374; BDBM50421524
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.66E+14 nM
|
[17] | |||
| Compound Name |
3-Nitro-N'-({5-nitro-2-furyl}methylene)benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416237; 3-nitro-N'-[(5-nitro-2-furyl)methylene]benzohydrazide; SCHEMBL13497010; BDBM50421528; STK730887; ZINC33384227; AKOS001017268; MCULE-5014798481; ST030769; 5-nitro-furfural-(3-nitro-benzoylhydrazone); AG-205/09848038; 3-nitro-N'-[(E)-(5-nitrofuran-2-yl)methylidene]benzohydrazide; 3-nitro-N'~1~-[(E)-1-(5-nitro-2-furyl)methylidene]benzohydrazide; N-[(1E)-2-(5-nitro(2-furyl))-1-azavinyl](3-nitrophenyl)carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 2.00E+14 nM
|
[17] | |||
| Compound Name |
N-[(E)-[5-(2-Chlorophenyl)furan-2-yl]methylideneamino]-3-hydroxynaphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39161; BDBM50421533
Click to Show/Hide
|
||||
| Activity |
IC50 = 1.66E+15 nM
|
[17] | |||
| Compound Name |
N-[(E)-[4-(Dimethylamino)naphthalen-1-yl]methylideneamino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39814; BDBM50421526
Click to Show/Hide
|
||||
| Activity |
IC50 = 2.00E+15 nM
|
[17] | |||
| Compound Name |
3-Hydroxy-7-methoxy-N-[(E)-[5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methylideneamino]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39253; BDBM50421530
Click to Show/Hide
|
||||
| Activity |
IC50 = 5.01E+15 nM
|
[17] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
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| REF 2 | Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease. J Med Chem. 2010 Jan 14;53(1):37-51. | ||||
| REF 3 | Colloidal aggregation causes inhibition of G protein-coupled receptors. J Med Chem. 2013 Mar 28;56(6):2406-14. | ||||
| REF 4 | Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. J Med Chem. 2008 Apr 24;51(8):2502-11. | ||||
| REF 5 | Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3527-30. | ||||
| REF 6 | In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives. J Med Chem. 2007 Nov 29;50(24):6004-15. | ||||
| REF 7 | Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi. Bioorg Med Chem. 2016 Sep 15;24(18):4228-4240. | ||||
| REF 8 | Divergent modes of enzyme inhibition in a homologous structure-activity series. J Med Chem. 2009 Aug 27;52(16):5005-8. | ||||
| REF 9 | Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents. Eur J Med Chem. 2012 Aug;54:512-21. | ||||
| REF 10 | Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification. Bioorg Med Chem. 2017 Mar 15;25(6):1889-1900. | ||||
| REF 11 | Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents. J Med Chem. 2014 Mar 27;57(6):2380-92. | ||||
| REF 12 | New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle. Bioorg Med Chem. 2008 Jul 15;16(14):6995-7004. | ||||
| REF 13 | Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties. Eur J Med Chem. 2017 Aug 18;136:223-234. | ||||
| REF 14 | Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6218-21. | ||||
| REF 15 | A comparative study of warheads for design of cysteine protease inhibitors. Bioorg Med Chem Lett. 2017 Nov 15;27(22):5031-5035. | ||||
| REF 16 | Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids as -lactamase inhibitors. J Med Chem. 2010 Nov 11;53(21):7852-63. | ||||
| REF 17 | CoMFA and HQSAR of acylhydrazide cruzain inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1537-41. | ||||
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