Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T25663 | Target Info | |||
| Target Name | Adenosine receptor (ADOR) | ||||
| Synonyms |
P1 receptor
Click to Show/Hide
|
||||
| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
ATL-844
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(4-Cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide; MRS 1754; 264622-58-4; MRS-1754; MRS1754; CHEMBL273807; N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide; N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide; [3H]MRS1754; [3H]-MRS1754; NCGC00015689-01; Lopac-M-6316; Lopac0_000729; GTPL453; GTPL449; MLS002153324; SCHEMBL1222380; AC1O7G54; CTK8E7916; CHEBI:93269; AOB5542; DTXSID80424967; MolPort-023-276-567; HMS3373J21; HMS3268F13; HMS2230A06; ZINC4475274; BDBM50086170; AKOS027427086; AKOS024457276; EX-3306; ATL-618; ATL-GW-22; ATL-GW-8; A2B adenosine receptor antagonists, Adenosine/Ortho-McNeil; A2B adenosine receptor antagonists (oral, asthma/diabetes), Adenosine Therapeutics; A2B adenosine receptor antagonists (oral, asthma/diabetes), Clinical Data
Click to Show/Hide
|
||||
| Activity |
EC50 = 67608.3 nM
|
[1] | |||
| Compound Name |
Chembl4167064
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50282637; ZINC71886147; AKOS033113715; MCULE-4070916921; Z1151205940; N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]oxy}acetamide
Click to Show/Hide
|
||||
| Activity |
EC50 = 61659.5 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Nanomolar anti-sickling compounds identified by ligand-based pharmacophore approach. Eur J Med Chem. 2017 Aug 18;136:487-496. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.