Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T22956 | Target Info | |||
| Target Name | Cyclin-dependent kinase 3 (CDK3) | ||||
| Synonyms |
Cyclindependent kinase 3; Cell division protein kinase 3; CDKN3
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| Target Type | Clinical trial Target | ||||
| Gene Name | CDK3 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL522760; SCHEMBL3133068; BDBM50267565; 3-(6-chloro-5-fluoro-1-methylindol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)pyrrole-2,5-dione
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | From a natural product lead to the identification of potent and selective benzofuran-3-yl-(indol-3-yl)maleimides as glycogen synthase kinase 3beta inhibitors that suppress proliferation and survival of pancreatic cancer cells. J Med Chem. 2009 Apr 9;52(7):1853-63. | ||||
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