Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T22496 | Target Info | |||
| Target Name | Huntingtin (HTT) | ||||
| Synonyms |
IT15; Huntington disease protein; HD protein; HD
Click to Show/Hide
|
||||
| Target Type | Clinical trial Target | ||||
| Gene Name | HTT | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-Benzyl-6-bromoquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494326; Neuro1_000498; Oprea1_305593; MLS000533819; cid_720645; SCHEMBL17845927; HMS2309K19; ZINC122248; N-benzyl-6-bromo-4-quinazolinamine; (6-bromoquinazolin-4-yl)benzylamine; BDBM50257751; STL332021; AKOS002262821; MCULE-7465908850; BCB03_000906; SMR000141257; EU-0077269; ST50182387; SR-01000485099; CU-01000086199-2; SR-01000485099-1; F0920-1649
Click to Show/Hide
|
||||
| Activity |
EC50 = 50000 nM
|
[1] | |||
| Compound Name |
6-Bromo-N-propylquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL449571; 4-Quinazolinamine, 6-bromo-N-propyl-; Oprea1_242568; Oprea1_669601; SCHEMBL4359487; ZINC1778621; (6-bromoquinazolin-4-yl)propylamine; BDBM50257749; AKOS002257558; MCULE-8496551446; BCB03_000907; ST50195164; CU-00000000403-1; BRD-K50640845-001-01-4
Click to Show/Hide
|
||||
| Activity |
EC50 = 50000 nM
|
[1] | |||
| Compound Name |
6-Bromo-N-(prop-2-en-1-yl)quinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMER28; SMER 28; N-Allyl-6-bromoquinazolin-4-amine; 6-bromo-N-prop-2-enylquinazolin-4-amine; SMER-28; 6-Bromo-N-2-propenyl-4-quinazolinamine; 6-bromo-N-prop-2-enyl-4-quinazolinamine; CHEMBL494325; 4-Quinazolinamine, 6-bromo-N-2-propen-1-yl-; MFCD02166825; 6-bromo-N-2-propen-1-yl-4-quinazolinamine; C11H10BrN3; SMR000106755; CBMicro_021891; SMER26; Cambridge id 6164173; Oprea1_603374; MLS000110826; SMER-28;SMER 28; SCHEMBL13283266; cid_1560402; CTK8E6903; KS-00000TKR; DTXSID10364408; 4-(allylamino)-6-bromoquinazoline; HMS2384I08; HMS3263K19; SMER28 (2); BCP17486; EX-A1017; N-allyl-6-bromo-4-quinazolineamine; ZINC1766166; Tox21_501019; Allyl-(6-bromoquinazolin-4-yl)amine; BDBM50257750; CCG-14477; s8240; STK975188; AKOS002262854; SMER28, >99% (HPLC), solid; CS-5731; LP01019; MCULE-7864435735; SDCCGSBI-0021786.P002; NCGC00079175-02; NCGC00079175-07; NCGC00261704-01; AK541286; AS-65723; BCB03_000905; (6-bromoquinazolin-4-yl)prop-2-enylamine; BIM-0021786.P001; HY-100200; B7637; EU-0073802; M3106; ST50182394; PK04_181104; SR-01000453166; CU-01000047511-3; J-018126; SR-01000453166-1; BRD-K08478539-001-01-3; BRD-K08478539-001-02-1; Q27165697
Click to Show/Hide
|
||||
| Activity |
EC50 = 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Potent inhibitors of Huntingtin protein aggregation in a cell-based assay. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1715-7. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.