Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T13910 | Target Info | |||
| Target Name | Phosphofructokinase 2 (PFK2) | ||||
| Target Type | Clinical trial Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
5-(4-Amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]imidazol-2-yl)furan-2-ylphosphonic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL570790; SCHEMBL4129250; BDBM50303854; [5-[4-amino-7-ethyl-5-fluoro-1-(2-methylpropyl)benzimidazol-2-yl]furan-2-yl]phosphonic acid
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| Activity | Phosphofructokinase muscle type |
EC50 ~ 100000 nM
|
[1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics. J Med Chem. 2010 Jan 14;53(1):441-51. | ||||
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