Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T13348 | Target Info | |||
| Target Name | AP endonuclease 1 (APEX1) | ||||
| Synonyms |
Redox factor-1; REF1; REF-1; HAP1; DNA-(apurinic or apyrimidinic site) lyase; Apurinic-apyrimidinic endonuclease 1; APX; APEX nuclease; APEX; APEN; APE1; APE-1; APE
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| Target Type | Clinical trial Target | ||||
| Gene Name | APEX1 | ||||
| Biochemical Class | Alpha-carbonic anhydrase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 131 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-[3-(2-Carboxyethyl)-5-methyl-5-nitro-1,3-diazinan-1-yl]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
BAS 01367241; Oprea1_499344; Oprea1_585044; CHEMBL468905; ZINC19321779; AKOS000641314; MCULE-2982260727; SR-01000312653; SR-01000312653-1
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
[7-(Carboxymethyl-sulfamoyl)-9-oxo-9H-fluorene-2-sulfonylamino]-acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CBMicro_029396; Oprea1_074540; Oprea1_521020; MLS001202686; CHEMBL468072; C17H14N2O9S2; HMS2839F07; CCG-2805; ZINC1814192; STK726916; AKOS000581541; MCULE-9737460308; SMR000514488; BIM-0029383.P001; ST50323069; SR-01000506465; SR-01000506465-1
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
Fluorene-9,9-dipropionic acid
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Investigative | Compound Info | ||
| Synonyms |
3,3'-(9H-fluorene-9,9-diyl)dipropanoic acid; 9,9'-Fluorenedipropionic acid; 3-[9-(2-carboxyethyl)fluoren-9-yl]propanoic acid; NSC 68859; BRN 2003967; Propionic acid, 3,3'-fluoren-9-ylidenedi-; 9,9-BIS(2-CARBOXYETHYL)FLUORENE; Oprea1_394318; Oprea1_688352; MLS001203767; CHEMBL511379; SCHEMBL5866539; 99FLUORENEDIPROPIONICACID; 3-[9-(2-Carboxy-ethyl)-9H-fluoren-9-yl]-propionic acid; DTXSID50196083; HMS2819H10; NSC68859; ZINC4713544; MFCD00045334; NSC-68859; STL200129; AKOS002242701; MCULE-2158109600; WLN: L B656 HHJ H2VQ H2VQ; Propionic acid,3'-fluoren-9-ylidenedi-; NCGC00245132-01; AS-41176; SMR000514196; ST45180293; 3,3'-(9H-Fluoren-9-ylidene)dipropionic acid; SR-01000313156; SR-01000313156-1; 3,3-(9H-FLUORENE-9,9-DIYL)DIPROPANOIC ACID
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
(2E)-2-{(2E)-[4-(1,3-Benzodioxol-5-yl)butan-2-ylidene]hydrazinylidene}-4-oxo-1,3-thiazinane-6-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL461841; HMS1679D15; STL018861; STL319501; AKOS000589656; AKOS022087503; AKOS022096019; ST50249922
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
3-[(2-Carboxycyclohexyl)carbonylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
ChemDiv3_001569; CBKinase1_000057; CBKinase1_012457; Oprea1_559473; Oprea1_843750; CHEMBL468074; 3-[(2-Carboxy-cyclohexanecarbonyl)-amino]-benzoic acid; HMS1477H07; SBB041181; STK447046; AKOS000269553; AKOS016039409; MCULE-5074174480; IDI1_020535; ST45174826; 3-(2-carboxycyclohexanecarboxamido)benzoic acid; Benzoic acid, 3-(2-carboxycyclohexanoylamino)-; 3-{[(2-carboxycyclohexyl)carbonyl]amino}benzoic acid; 3-([(2-Carboxycyclohexyl)carbonyl]amino)benzoic acid #
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| Activity |
IC50 = 55000 nM
|
[1] | |||
| Compound Name |
N-(3-(Benzo[d]thiazol-2-yl)thieno[2,3-c]pyridin-2-yl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057951; SCHEMBL13735857; BDBM50388259; NCGC00185088-01; N-[3-(1,3-benzothiazol-2-yl)thieno[2,3-c]pyridin-2-yl]acetamide
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
N-(3-Naphthalen-1-yl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2059403; SCHEMBL13832536; BDBM50388232; NCGC00186089-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
N-[3-(1,3-Benzothiazol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]-3-phenylpropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057938; BDBM50388245
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
2-[3-(1,3-Benzothiazol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]-5-methyl-1,3,4-oxadiazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057946; SCHEMBL13736856; BDBM50388256; NCGC00189084-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
N-[3-(1,3-Benzothiazol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]-2,2-dimethylpropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057934; BDBM50388243
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
N-[3-(1H-Indol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057929; SCHEMBL13740075; BDBM50388240; NCGC00187565-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
3-(1,3-Benzothiazol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-2-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057945; BDBM50388255; NCGC00189088-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
Methyl 3-(1,3-benzothiazol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057944; SCHEMBL13735674; BDBM50388254; NCGC00189086-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
Tert-butyl 2-acetamido-3-(benzo[d]thiazol-2-yl)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1879618; SCHEMBL13832432; BDBM50388237; NCGC00184828-01; tert-butyl 2-acetamido-3-(1,3-benzothiazol-2-yl)-5,7-dihydro-4H-thieno[2,3-c]pyridine-6-carboxylate
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
N-[3-(1-Benzothiophen-3-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2059407; SCHEMBL13737888; BDBM50388239; NCGC00186099-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
5-[3-(1,3-Benzothiazol-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]-3-methyl-1,2,4-oxadiazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057947; SCHEMBL13736085; BDBM50388233; NCGC00189083-01
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| Activity |
IC50 ~ 57000 nM
|
[2] | |||
| Compound Name |
3-[[5-(Tert-butyl)-4-methyl-1,3-thiazol-2-yl](2-carboxyethyl)amino]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL467863; ZINC3074258; AKOS000620094; MCULE-3562127841
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| Activity |
IC50 = 60000 nM
|
[1] | |||
| Compound Name |
1H-Benzimidazole-2-propanoic acid, 6-carboxy-
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Investigative | Compound Info | ||
| Synonyms |
ChemDiv3_004256; CHEMBL461842; SCHEMBL6473944; 2-(2-carboxyethyl)-3H-benzimidazole-5-carboxylic acid; 2-(2-Carboxy-ethyl)-1H-benzoimidazole-5-carboxylic acid; HMS1485B10; ZINC794584; AKOS000636639; CCG-114247; IDI1_022166
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
3-[(1,1-Dioxo-1,4-thiazinan-4-yl)sulfonyl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL450862; ZINC806164; AKOS000729276; SR-01000364443; SR-01000364443-1
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
3-(2-Oxo-6-sulfo-1,3-benzoxazol-3-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL442876; ZINC5046241; AKOS000511094; SR-01000317830; SR-01000317830-1
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
N-[4-(5-Ethyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-succinamic acid
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Investigative | Compound Info | ||
| Synonyms |
BAS 00549540; Oprea1_087592; Oprea1_712466; MLS001210531; CHEMBL512214; HMS2835L22; ZINC2350447; STL299925; AKOS000601889; MCULE-5770633125; SMR000514611; SR-01000361681; SR-01000361681-1
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
3-{3-[3-(2-Chloro-benzyl)-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]-piperidine-1-sulfonyl}-benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
SMR000602207; MLS001219340; MLS003908991; CHEMBL460570; HMS2909C14; AKOS000766619
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| Activity |
IC50 = 87000 nM
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[1] | |||
| Compound Name |
2-[[5-[4-(Methanesulfonamido)phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL452114
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
[2-Methyl-4-(morpholin-4-ylsulfonyl)phenoxy]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
[2-Methyl-4-(morpholine-4-sulfonyl)-phenoxy]-acetic acid; CHEMBL469109; HMS1699I18; ZINC4937907; BBL002719; MFCD07396471; STK802693; AKOS000111423; MCULE-3850654340; BB 0238569; H5051; A1-13251; [2-Methyl-4-(morpholine-4-sulfonyl)-phenoxy]- acetic acid
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| Activity |
IC50 = 100000 nM
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[1] | |||
| Compound Name |
Butyl 4-[[2-(1-ethyltetrazol-5-yl)sulfanylacetyl]amino]benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL459938; ZINC4168772; AKOS000738028; MCULE-8861688455
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
N-(4-Ethylsulfonyl-6-methyl-1,2,3,4-tetrahydrocyclopenta[a]inden-7-yl)ethanesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL506221
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
4-(3,5-Dioxo-2,3,4,5-tetrahydro-[1,2,4]triazin-6-ylamino)-butyric acid
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Investigative | Compound Info | ||
| Synonyms |
BAS 00837338; ChemDiv3_000919; MLS000716099; CHEMBL447958; HMS1475J17; HMS2639D22; HMS3360A14; ZINC1808108; AKOS000533277; CCG-104986; MCULE-6901609712; IDI1_019885; SMR000277616; ST50005247; 4-[(3,5-dioxo-2H,4H-1,2,4-triazin-6-yl)amino]butanoic acid; 4-((3,5-Dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)amino)butanoic acid
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-(2-Hydroxy-phenyl)-3-(pyrrolidine-1-sulfonyl)-benzamide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_240664; Oprea1_381828; CHEMBL461209; HMS1610M13; ZINC182687; ZINC00182687; AKOS000729113; MCULE-8563487542; EU-0004893; AB00115382-01; SR-01000432523; SR-01000432523-1
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-N-[(2-Fluorophenyl)methyl]-1-N,1-N-dimethyl-4-N-(2-methylcyclohexyl)benzene-1,4-disulfonamide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_586116; CHEMBL467849
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
[2-Methoxy-4-(2H-tetrazol-5-yl)phenoxy]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL461634; 2-(2-methoxy-4-(2H-tetrazol-5-yl)phenoxy)acetic acid; SCHEMBL12892200; ZINC5526672; BBL020009; MFCD03722326; STL163677; AKOS000521264; AKOS024298618; MCULE-6670648804; VS-07065; H4504; 2-[2-methoxy-4-(2H-1,2,3,4-tetrazol-5-yl)phenoxy]acetic acid
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
2-(5-(((5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL460354; ZINC9010513; AKOS000587853; MCULE-2344046289; SR-01000355740; SR-01000355740-1; 2-{5-[5-(2-Nitro-phenyl)-[1,3,4]oxadiazol-2-ylmethylsulfanyl]-[1,3,4]oxadiazol-2-yl}-phenol
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-(5-(2-Nitrophenyl)furan-2-yl)-2-(phenylsulfonyl)acrylonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL518673; ZINC732027; STK701610; AKOS000526188; (2E)-3-[5-(2-nitrophenyl)-2-furyl]-2-(phenylsulfonyl)-2-propenenitrile; (2E)-3-[5-(2-nitrophenyl)furan-2-yl]-2-(phenylsulfonyl)prop-2-enenitrile
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5-[1-(Benzenesulfonyl)piperidin-3-yl]-3-(4-fluorophenyl)-1,2,4-oxadiazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL516612; AKOS000766844; AKOS017253777; SR-01000332337; SR-01000332337-1
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
N-(1,3-Benzodioxol-5-ylmethyl)-2,5-diethoxy-4-(tetrazol-1-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_017649; Oprea1_153669; CHEMBL468480; ZINC1325384; AKOS000705972
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
1-N-Benzyl-4-N-[(4-chlorophenyl)methyl]-4-N-(furan-2-ylmethyl)benzene-1,4-disulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL461424; SCHEMBL20387946; ZINC33355670; AKOS000653452; MCULE-2579844350; Benzene-1,4-disulfonic acid 1-benzylamide 4-[(4-chloro-benzyl)-furan-2-ylmethyl-
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Methyl 2-(4-{ethyl[(4-methylphenyl)sulfonyl]amino}phenyl)-3,3,3-trifluoro-2-hydroxypropanoate
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Investigative | Compound Info | ||
| Synonyms |
MLS000123238; CHEMBL462059; HMS2441A18; STK366804; AKOS001686829; MCULE-2159534652; SMR000123892; EU-0016175; ST50904382
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-[1,3,7-Tris(morpholin-4-ylsulfonyl)benzotriazolo[2,1-a]benzotriazol-5-ium-6-id-9-yl]sulfonylmorpholine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL508178; AKOS000748914
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-{2-[4-Methyl-5-(pyridin-3-ylmethylsulfanyl)-4H-[1,2,4]triazol-3-yl]-ethyl}-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
MLS001223494; CHEMBL468909; HMS2911B04; SMR000605530; SR-01000349694; SR-01000349694-1
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
(4-Hydroxy-1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-ylamino)-acetic acid
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Investigative | Compound Info | ||
| Synonyms |
SBB015208; n-(4-hydroxy-1,1-dioxidotetrahydro-3-thienyl)glycine; 2-[(4-hydroxy-1,1-dioxothiolan-3-yl)amino]acetic acid; (4-Hydroxy-1,1-dioxidotetrahydrothiophen-3-yl)glycine; (4-Hydroxy-1,1-dioxo-tetrahydrothiophen-3-ylamino)-acetic acid; (4-hydroxy-1,1-dioxo-tetrahydro-1lambda6-thiophen-3-ylamino)-acetic acid; N-(4-hydroxy-1,1-dioxidotetrahydrothiophen-3-yl)glycine; CHEMBL447590; CTK4G3359; DTXSID80378198; (4-Hydroxy-1,1-Dioxo-Tetrahydro-1-Thiophen-3-Yl-Amino)-Acetic Acid; MFCD00456643; AKOS000269587; AKOS016039524; MCULE-9237617008; ST090291; (3-hydroxy-1,1-dioxothiolan-4-ylamino)acetic acid; n-(4-hydroxy-1,1-dioxidotetrahydrothien-3-yl)glycine; 2-[(1,4-dihydroxy-1-oxothiolan-3-yl)amino]acetic acid; F1068-0096; (4-hydroxy-1,1-dioxo-tetrahydro-1-thiophen-3-ylamino)-acetic acid; 2-((4-Hydroxy-1,1-dioxidotetrahydrothiophen-3-yl)amino)acetic acid
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[5-[2-(4-Methylphenyl)sulfonylethyl]-1,3,4-thiadiazol-2-yl]-3-phenylpropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL461851; ZINC1340294; AKOS000702789; MCULE-6280593988
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[(Furan-2-carbonyl)-amino]-4-methyl-thiazole-5-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
MLS001222113; CHEMBL512048; SCHEMBL3587905; HMS2903C10; ZINC1330440; 2-(furan-2-carbonylamino)-4-methyl-1,3-thiazole-5-carboxylic acid; AKOS000780779; MCULE-2646944512; SMR000601884; SR-01000329467; SR-01000329467-1; BRD-K16516351-001-08-0; 2-(furan-2-carboxamido)-4-methylthiazole-5-carboxylic acid; 2-(2-Furoylamino)-4-methyl-1,3-thiazole-5-carboxylic acid
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
(2E)-3-{3-[(1,1-Dioxidotetrahydrothiophen-3-yl)sulfamoyl]-4-methoxyphenyl}prop-2-enoic acid
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Investigative | Compound Info | ||
| Synonyms |
MLS000714812; CHEMBL448868; HMS2682M11; STK806274; AKOS000522221; AKOS016323647; SMR000274791; ST50775781; AB00588656-02; F0219-0027
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[[4-(Cyclopropylsulfamoyl)phenyl]sulfonyl-(thiophen-2-ylmethyl)amino]-N-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468691; ZINC13496927; AKOS000719103
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-(5-{[5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-yl]methylthio}-1H-1,2,4-triazol-3-y l)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL462696; ZINC8435628; AKOS000587854; MCULE-7656425776; ST50259985; SR-01000359471; SR-01000359471-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5-[1-(4-Fluoro-benzenesulfonyl)-piperidin-3-yl]-3-(4-fluoro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001222647; CHEMBL459310; HMS2887G23; AKOS000765144; MCULE-9835752753; SMR000602205
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[2-(3-Sulfopropylsulfanyl)-1,3-benzothiazol-3-ium-3-yl]propane-1-sulfonic acid;chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL541931
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[[5-[2-(Azepan-1-yl)-2-oxoethyl]sulfanyl-4-(4-fluorophenyl)-1,2,4-triazol-3-yl]methyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517894
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[[4-(Furan-2-ylmethyl)-5-(4-morpholin-4-ylsulfonylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460792; AKOS000793783
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Methyl 2-[[5-[4-(methanesulfonamido)phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL504860
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-{[5-Benzyl-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460993; ZINC4519823; STK218806; AKOS000632463; MCULE-1803170821
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[3-(Furan-2-carbonyl)indol-1-yl]-N-(pyridin-3-ylmethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BAS 09623431; CHEMBL511913; ZINC4458608; AKOS000596269; SR-01000367914; SR-01000367914-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
{1-[(4-Fluorophenyl)sulfonyl]pyrrolidin-2-yl}-N-[5-(methylethyl)(1,3,4-thiadia zol-2-yl)]carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517260; AKOS002308575; AKOS016321925; ST50767200
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[5-(Diethylsulfamoyl)-2-methoxyphenyl]oxolane-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBKinase1_004485; CBKinase1_016885; MLS000715472; CHEMBL459529; HMS2735P07; STK136369; AKOS000652644; AKOS017043448; MCULE-4158972365; SMR000275451; ST50281709; BRD-A43823424-001-01-7; Z27341613; N-[5-(diethylsulfamoyl)-2-methoxyphenyl]tetrahydrofuran-2-carboxamide; N-{5-[(diethylamino)sulfonyl]-2-methoxyphenyl}oxolan-2-ylcarboxamide; N-{5-[(diethylamino)sulfonyl]-2-methoxyphenyl}tetrahydro-2-furancarboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(2-Chlorophenyl)methyl]-3-methoxy-N-(pyridin-3-ylmethyl)-4-(tetrazol-1-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL512985; ZINC934149; AKOS000803640
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3,3'-(2-Oxo-cyclohexylidene)-di-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_058023; Oprea1_124464; CHEMBL466003; SCHEMBL12541025; HMS1675B18; ZINC4902890; AKOS000640043; SR-01000313335; SR-01000313335-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-Methyl-3-(phenylsulfonyloxy)phenyl benzenesulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460995; ZINC2590959; AKOS000732601; MCULE-8816376396; ST45155795; AG-205/32661052; Z56857857; 2-methyl-3-[(phenylsulfonyl)oxy]phenyl benzenesulfonate; 3-[(benzenesulfonyl)oxy]-2-methylphenyl benzenesulfonate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
(2-Thienylsulfonyl){4-[(2-thienylsulfonyl)amino]phenyl}amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461010; ZINC1795676; STK981849; AKOS000594436; MCULE-6720860425; ST50277606; N,N'-benzene-1,4-diyldithiophene-2-sulfonamide; N-{4-[(thien-2-ylsulfonyl)amino]phenyl}thiophene-2-sulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(5Z)-5-[3-Ethyl-5-(trifluoromethylsulfonyl)-1,3-benzothiazol-2-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468890; AKOS000732585; ZINC100199814
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-(4-Fluorophenyl)-4-[methyl(phenylsulfonyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_086388; Oprea1_287584; CHEMBL467848; ZINC854630; STL197735; AKOS000387071; MCULE-4038430341; SR-01000441063; SR-01000441063-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[[5-(Ethylcarbamoyl)-2-methylthiophen-3-yl]sulfonylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459301; ZINC6680063; AKOS000762995
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4,4'-Diaminobiphenyl-3,3'-disulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,3'-Benzidinedisulfonic acid; 2-amino-5-(4-amino-3-sulfophenyl)benzenesulfonic acid; UNII-8W0E505HS1; 4,4'-DIAMINO-[1,1'-BIPHENYL]-3,3'-DISULFONIC ACID; NSC3740; 8W0E505HS1; 4,4'-Diaminediphenyl-(1,1')-3,3'-disulfonic acid; 4,4'-DIAMINO-3,3'-BIPHENYLDISULFONIC ACID; 4,4'-Diamino-(1,1'-biphenyl)-3,3'-disulfonic acid; [1,1'-Biphenyl]-3,3'-disulfonicacid, 4,4'-diamino-; 4,4'-diaminobiphenyl-3,3'-disulphonic acid; NSC 3740; 4,3'-disulfonic acid; 3, 4,4'-diamino-; SCHEMBL714945; CHEMBL467238; 3, 3'-Benzidinedisulfonic acid; CTK1C2502; 4,1')-3,3'-disulfonic acid; DTXSID70187332; (1,1'-Biphenyl)-3,3'-disulfonic acid, 4,4'-diamino- (9CI); NSC-3740; ZINC1672824; STK064595; AKOS000520862; MCULE-5737595332; [1,3'-disulfonic acid, 4,4'-diamino-; DB-098504; CS-0110604; ST50233551; 3,3'-Biphenyldisulfonic acid, 4, 4'-diamino-; SR-01000313381; SR-01000313381-1; 3,3'-Biphenyldisulfonic acid, 4,4'-diamino- (8CI); 4,4'-Diamino[1,1'-biphenyl]-3,3'-disulfonic acid; Q27271099; 2-amino-5-(4-amino-3-sulfo-phenyl)benzenesulfonic acid; {[1,1'-Biphenyl]-3,3'-disulfonic} acid, 4,4'-diamino-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[Methyl(naphthalen-2-ylsulfonyl)amino]-N-[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468490; ZINC13567043; AKOS000756209; MCULE-5663896091
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[[3-[(3-Nitrophenyl)sulfonylamino]quinoxalin-2-yl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL516484; SCHEMBL1792614; ZINC6089034; STL297576; AKOS022142172; MCULE-2535124467; 3-[(3-{[(3-nitrophenyl)sulfonyl]amino}quinoxalin-2-yl)amino]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[[4-Benzyl-5-(4-piperidin-1-ylsulfonylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_714820; CHEMBL518027; ZINC904734; AKOS000795526; MCULE-6676123432
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5-{[(3-Carboxy-5-methyl(2-furyl))methylthio]methyl}-2-methylfuran-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL511372; SCHEMBL13402271; ZINC4892763; AKOS000641680; MCULE-2120657949; ST057327; SR-01000360947; SR-01000360947-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[(7-Cyclopropyl-13-methyl-10-thia-3,4,6,8-tetrazatetracyclo[7.7.0.02,6.011,16]hexadeca-1(9),2,4,7,11(16)-pentaen-5-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461850; AKOS000677525; AKOS024308245; MCULE-4794456255
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-Chloro-N-(2-hydroxyphenyl)-5-piperidin-1-ylsulfonylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBMicro_037060; Oprea1_529638; Oprea1_710624; CHEMBL461852; SCHEMBL17479136; DTXSID40386890; ZINC4838440; 2-Chloro-N-(2-hydroxy-phenyl)-5-(piperidine-1-sulfonyl)-benzamide; MCULE-5997469956; BIM-0036915.P001; SR-01000413017; SR-01000413017-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-N-Benzyl-4-N-ethyl-1-N-(4-methylcyclohexyl)benzene-1,4-disulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ZINC01367871; CHEMBL467646; ZINC1367871; AKOS000787761; MCULE-5004563481
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-({4-[(7,9-Dioxo-6,10-dioxaspiro[4.5]dec-8-ylidene)methyl]-2-iodo-6-methoxyphenoxy}methyl)benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468683; ZINC6906535; STK378419; AKOS000625481; MCULE-9038062987; ST50251551
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
[2-(Furan-2-ylmethylene-hydrazono)-4-oxo-thiazolidin-5-yl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL505114; SCHEMBL8290548; SBB039708; AKOS000268021; AKOS016371145; BIM-0026936.P001; ST50069352; MLS-0445771.0001; AB00076029-01
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[2-Chloro-4-(toluene-4-sulfonylamino)-phenyl]-2-piperidin-1-yl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMR000123135; ASN 01516572; MLS000523157; MLS002536226; CHEMBL459727; HMS2420K11; ZINC892342; AKOS000722961; MCULE-9380417480; BRD-K74462554-001-07-3
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-{2-Methyl-4-[(propylamino)sulfonyl]phenoxy}-N~1~-(tetrahydro-2-furanylmethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468491; STL196409; AKOS000433517; AKOS021687848; MCULE-5001029117; 2-[2-methyl-4-(propylsulfamoyl)phenoxy]-N-(tetrahydrofuran-2-ylmethyl)acetamide; 2-{2-methyl-4-[(propylamino)sulfonyl]phenoxy}-N~1~-(tetrahydro-2-furanylmethyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000122919; Oprea1_579721; Oprea1_746543; CHEMBL459302; ZINC84728; 3-(Benzo[1,2,5]thiadiazole-4-sulfonylamino)-benzoic acid; 3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)benzoic acid; HMS2461P09; BBL029507; STK331893; AKOS000541428; AKOS001409656; MCULE-2152099504; SMR000123600; VS-09272; AB00775192-01; SR-01000429631; SR-01000429631-1; 3-(2,1,3-BENZOTHIADIAZOLE-4-SULFONAMIDO)BENZOIC ACID
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-[(Carboxymethyl)sulfanyl]-3-nitrobenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(4-CARBOXY-2-NITROPHENYLTHIO)ACETIC ACID; 4-(carboxymethylthio)-3-nitrobenzoic acid; 4-(carboxymethylsulfanyl)-3-nitrobenzoic acid; 4-Carboxymethylsulfanyl-3-nitro-benzoic acid; Oprea1_207852; Oprea1_566422; CHEMBL466206; CTK7J5650; ZINC58224; MFCD00183080; SBB000958; STK370677; AKOS000117400; MCULE-3576376399; NE52322; ST50052147; EN300-11847; AF-962/02747014; SR-01000361320; SR-01000361320-1; Z56823254
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
Diethyl bis[2-(2H-tetrazol-5-yl)ethyl]propanedioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL500986; ZINC3767007; STL445935; AKOS000732028; MCULE-3995319372; 3,3-bis(ethoxycarbonyl)-1,5-bis(5-tetrazolyl)pentane
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-(1H-tetrazol-5-yl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460572; ZINC4785334; STK239163; AKOS000466308; MCULE-9960066776; ST091747; N-(1H-1,2,3,4-tetraazol-5-yl)-3-[3-(4-chlorophenyl)(1,2,4-oxadiazol-5-yl)]prop anamide; 3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-N~1~-(1H-1,2,3,4-tetraazol-5-yl)propanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-(3-Allyl-5-benzyl-4-oxo-thiazolidin-2-ylideneamino)-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBMicro_026257; MLS000553707; CHEMBL459939; HMS2526A06; AKOS000534059; AKOS002771634; AKOS016130128; MCULE-8215922155; SMR000171572; BIM-0026264.P001
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
3-[(2-Chlorophenyl)methyl]-5-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-yl]-6H-triazolo[4,5-d]pyrimidin-7-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467859; ZINC06173104; AKOS000775737; AKOS024318504
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
6-[(2-Carboxy-2-phenylacetyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_245081; Oprea1_817833; CHEMBL460803
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[2-(Cyclopentylamino)-2-oxoethyl]-N-(4-methoxyphenyl)-5-oxothiolane-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467858
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5-(1-Benzenesulfonyl-piperidin-3-yl)-3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMR000124653; MLS000067183; MLS002537879; CHEMBL518797; HMS2493F21; AKOS000770372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-(Benzo[d]thiazol-2-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl methanesulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBMicro_011214; CHEMBL461208; SMSF0018185; ZINC2262030; STL323526; AKOS000531482; CB14326; MCULE-7228890357; BIM-0011358.P001; ST50468837; F0308-0807; 3-benzothiazol-2-yl-6-ethyl-2-methyl-4-oxochromen-7-yl methylsulfonate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[[5-(Dimethylsulfamoyl)-1H-indol-3-yl]methylidene]propanedioic acid diethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000703724; SMR000274089; diethyl 2-[[5-(dimethylsulfamoyl)-1H-indol-3-yl]methylidene]propanedioate; CHEMBL466179; BDBM72412; cid_3127906; REGID_for_CID_3127906; HMS2753H20; ZINC2765342; AKOS024347934; MCULE-3234745409; SR-01000359711; SR-01000359711-1; Q27196835; 2-[[5-(dimethylsulfamoyl)-1H-indol-3-yl]methylene]malonic acid diethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)carbonyl]glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
orotylglycine; SR-01000430228; TimTec1_002923; Oprea1_544277; CHEMBL460593; SCHEMBL21185585; ZINC969509; STK678822; AKOS000192425; MCULE-9457365112; SR-01000430228-1; 2-{[(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)carbonyl]amino}acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-(4-Ethylsulfonylpiperazin-1-yl)sulfonylbenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461839; SR-01000350492; SR-01000350492-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-(4-Propan-2-ylphenyl)-5-(1-propylsulfonylpiperidin-3-yl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ASN 06934608; CHEMBL467645; AKOS000766528; MCULE-3301028389; SR-01000332830; SR-01000332830-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-Methoxy-N-(2-methylcyclohexyl)-4-(tetrazol-1-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_174593; Oprea1_431970; MLS000715863; CHEMBL468481; AKOS000706023; SMR000277380
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(4-Bromophenyl)methyl]-N-(furan-2-ylmethyl)-3-methoxy-4-(tetrazol-1-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468059; ZINC934177; AKOS000802601
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-{5-[2-(2-Naphthylsulfonyl)ethyl](1,3,4-thiadiazol-2-yl)}benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_168767; Oprea1_535970; CHEMBL517101; ZINC866172; AKOS000731346; MCULE-9363323380; ST50003685; AB00091756-01
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[4-(2,3-Dihydro-1H-indol-1-ylsulfonyl)-2-methylphenoxy]-N~1~-(2-pyridylmethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL513531; STL196305; ZINC13566406; AKOS000428737; MCULE-3495859608; 2-[4-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2-methylphenoxy]-N-(pyridin-2-ylmethyl)acetamide; 2-[4-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2-methylphenoxy]-N~1~-(2-pyridylmethyl)acetamide
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
[(1,1-Dioxidotetrahydrothien-3-yl)thio]acetic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
2-[(1,1-dioxo-1lambda6-thiolan-3-yl)sulfanyl]acetic acid; Maybridge3_000612; CHEMBL475281; CTK8F2201; AKOS001127821; AKOS016047625; MCULE-7489455931; NE23873; IDI1_011999; EN300-13890; J-502671; BRD-A00360051-236-01-3; Z94601175; 2-((1,1-Dioxidotetrahydrothiophen-3-yl)thio)acetic acid; 2-[(1,1-dioxo-1??-thiolan-3-yl)sulfanyl]acetic acid
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[(2Z)-2-[(2E)-2-[3-Prop-2-enyl-2,4-bis(sulfanylidene)-1,3-thiazolidin-5-ylidene]ethylidene]-1,3-benzothiazol-3-yl]propane-1-sulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461009
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
S,S'-(1,3,4-Thiadiazole-2,5-diyl)bis(2-mercaptoethanesulfonic acid)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467239; ZINC6013677; AKOS030484490
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[2-(2-Phosphonophenoxy)ethoxy]phenylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
STK373203; Phosphonicacid, P,P'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis-; ACMC-20mr3c; CHEMBL469118; CTK0I3736; DTXSID00382737; ZINC2566639; AKOS001665444; MCULE-8824551858; ST50912690; [1,2-Ethanediylbis(oxy-2,1-phenylene)]bis(phosphonic acid); [ethane-1,2-diylbis(oxybenzene-2,1-diyl)]bis(phosphonic acid)
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[[5-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-1-piperidin-1-ylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459728; ZINC6194614; AKOS000728463; MCULE-8739129696
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5-Methyl 2-(tetrahydrofuran-2-ylmethyl) 3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2,5-dicarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000116526; CHEMBL448847; HMS2261E24; CCG-28144; STK405829; AKOS000662416; MCULE-9930222146; SMR000093496; ST50639356; SR-01000123832; SR-01000123832-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)-N-[(4-sulfamoylphenyl)methyl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_346146; Oprea1_454674; MLS000703671; CHEMBL466178; HMS1584N13; HMS2701E15; AKOS001726406; MCULE-8387507933; SMR000274036
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[2-Methyl-4-(morpholinosulfonyl)phenoxy]-N~1~-(4-pyridylmethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460581; ZINC4944007; STL196430; AKOS000433609; MCULE-3837529310; 2-[2-methyl-4-(morpholinosulfonyl)phenoxy]-N~1~-(4-pyridylmethyl)acetamide; 2-[2-methyl-4-(morpholin-4-ylsulfonyl)phenoxy]-N-(pyridin-4-ylmethyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-Cyclopentyl-3-methyl-4-tetrazol-1-yl-benzenesulfonamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
MLS001221878; CHEMBL513144; HMS2905H22; AKOS000706367; SMR000600233; SR-01000341374; SR-01000341374-1
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-Benzyl-5-(1-ethylsulfonylpiperidin-3-yl)-6H-triazolo[4,5-d]pyrimidin-7-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL459311; AKOS000766180; SR-01000346377; SR-01000346377-1
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Methyl [2-methyl-4-(piperidin-1-ylsulfonyl)phenoxy]acetate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BAS 08885877; CHEMBL452994; HMS1694G04; ZINC814002; STK229088; AKOS000426074; MCULE-2791000696; ST066246; SR-01000326648; SR-01000326648-1; methyl 2-[2-methyl-4-(piperidinosulfonyl)phenoxy]acetate; methyl 2-[2-methyl-4-(piperidylsulfonyl)phenoxy]acetate; [2-Methyl-4-(piperidine-1-sulfonyl)phenoxy]acetic acid, methyl ester
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Cambridge id 6252533
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMR000107686; MLS000111765; MLS002540485; CHEMBL511207; HMS2408I14; ZINC2969070; AKOS000526219; ST50248577; SR-01000466787; SR-01000466787-1; trans-5,5'-[(2-Butene-1,4-diyl)dithio]bis(1-phenyl-1,2,3,4-tetrazole)
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-(Thiophene-2-sulfonylamino)-benzoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
4-(thiophene-2-sulfonamido)benzoic acid; Benzoic acid, 4-[(2-thienylsulfonyl)amino]-; 4-[(2-thienylsulfonyl)amino]benzoic acid; 4-(thiophen-2-ylsulfonylamino)benzoic acid; CBMicro_033796; Oprea1_203165; Oprea1_517991; CHEMBL460801; SCHEMBL8266867; CTK3E2733; DTXSID20357967; ZINC440741; MFCD00493010; SBB018349; STK863121; AKOS000114652; MCULE-5496037583; NE45657; BIM-0033909.P001; ST50238889; 4-[(thiophen-2-ylsulfonyl)amino]benzoic acid; EN300-00279; Z45512288; 4-(thiophene-2-sulfonylamino)-benzoic acid, AldrichCPR; F0305-0045
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
6-Methyl-3-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl][1,2,4]triazolo[3,4-a]phthalazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBKinase1_005942; CBKinase1_018342; CHEMBL516778; SCHEMBL22680144; ZINC1425801; CCG-25445; STK777788; AKOS001689048; MCULE-5670867754; BRD-K10639804-001-01-4
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-O-Cyclopentyl 6-O-methyl 2,7-dimethyl-4-(2-methylphenyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3,6-dicarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467217; SCHEMBL5481053; STK404704; AKOS000666751; AKOS022029784; CCG-125959; MCULE-6318692406; ST50029846; UNM000000785801
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-(1,3-Benzothiazol-2-ylsulfanyl)-2-hydroxypropane-1-sulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460802
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-[2,5-Diethoxy-4-(tetrazol-1-yl)phenyl]-8-methoxy-2-oxochromene-3-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_291612; Oprea1_638139; CHEMBL511935; HMS1677D20; ZINC1342112; AKOS000706326; MCULE-6359278929
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-Chloro-5-{[(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetyl]amino}benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459300; ZINC4999539; STL381728; AKOS000421495; MCULE-5400333983; 2-chloro-5-{[(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetyl]amino}benzoic acid
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-({3-[(Diethylamino)sulfonyl]benzoyl}amino)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_141585; Oprea1_172023; CBDivE_007159; CHEMBL460994; ZINC754795; MCULE-3272089202; SR-01000326018; SR-01000326018-1
Click to Show/Hide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(3-Acetyl-1-ethylsulfonyl-2,6-dimethylindol-5-yl)ethanesulfonamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL460582; ZINC4945016; AKOS000738873; MCULE-9104638852
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[2-Methyl-4-(morpholine-4-sulfonyl)-phenoxy]-1-pyrrolidin-1-yl-ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001223004; CHEMBL448142; HMS2917J11; ZINC4513166; STL196455; AKOS000433644; MCULE-3902381384; SMR000613573; 2-[2-methyl-4-(morpholinosulfonyl)phenoxy]-1-(1-pyrrolidinyl)-1-ethanone; 2-[2-methyl-4-(morpholin-4-ylsulfonyl)phenoxy]-1-(pyrrolidin-1-yl)ethanone
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-Chloro-N-{5-[2-(2-naphthylsulfonyl)ethyl]-1,3,4-thiadiazol-2-yl}benzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
ChemDiv1_001297; Oprea1_317951; Oprea1_621049; CHEMBL459940; HMS590K21; ZINC866175; AKOS000730923; MCULE-9250711734; EU-0069234; SR-01000409765; SR-01000409765-1
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-[4-Ethyl-5-(2-pyrrolidin-1-ylethylsulfanyl)-1,2,4-triazol-3-yl]-1-methylsulfonylpiperidine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL513482; HMS1693H15; AKOS000770969
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[4-(4-Methyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)phenyl]methanesulfonamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL512561
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
{2-[(Methylsulfonyl)amino]-1,3-thiazol-4-yl}acetic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
(2-Methanesulfonylamino-thiazol-4-yl)-acetic acid; 2-[2-(methanesulfonamido)-1,3-thiazol-4-yl]acetic acid; 2-(2-methanesulfonamidothiazol-4-yl)-acetic acid; 2-(2-methanesulfonamido-1,3-thiazol-4-yl)acetic acid; (2-[(Methylsulfonyl)amino]-1,3-thiazol-4-yl)acetic acid; 2-{2-[(methylsulfonyl)amino]-1,3-thiazol-4-yl}acetic acid; 2-(2-(methylsulfonamido)thiazol-4-yl)acetic acid; CHEMBL502103; SCHEMBL9481455; CTK5B5299; DTXSID40390174; ALBB-015777; ZINC4384203; BBL013007; MFCD07186383; SBB085408; STK288420; AKOS000111552; MCULE-2478940367; VS-03640; 2-methanesulfonamidothiazol-4-ylacetic acid; AB0227831; DB-073147; BB 0238460; FT-0755569; R9562; ST50289337; EN300-27056; 2-(2-methanesulfonamidothiazol-4-yl)acetic acid; SR-01000325150; (2-Methanesulfonylamino-thiazol-4-yl)-acetic acid; 4-Thiazoleacetic acid, 2-[(methylsulfonyl)amino]-; SR-01000325150-1; BRD-K84161268-001-01-9; Z235344699; {2-[(Methanesulfonyl)amino]-1,3-thiazol-4-yl}acetic acid
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
1,3,6-Naphthalenetrisulfonic acid, 8-hydroxy-
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
zeta-Stat; 8-hydroxynaphthalene-1,3,6-trisulfonic acid; 1-Naphthol, 3,6,8-trisulfo-; NSC37044; 8-Hydroxynaphthalene-1,3,6-trisulphonic acid; zeta-Stat (ZETA-STAT); 1-Naphthol,6,8-trisulfo-; CBDivE_016138; CHEMBL453929; SCHEMBL2928135; DTXSID0062971; CTK1C3734; 1-Naphthol-3,8-trisulfonic acid; ZINC1669724; EINECS 222-008-5; 1-Naphthol-3,6,8-trisulfonic acid; NSC 37044; NSC-37044; 1-naphthol-3,6,8-trisulphonic acid; 1-Hydroxy-3,8-naphthalenetrisulfonic acid; HY-123979; 1,6-Naphthalenetrisulfonic acid, 8-hydroxy-; 1-Hydroxy-3,6,8-naphthalenetrisulfonic acid; 8-Hydroxy-1,3,6-naphthalenetrisulfonic acid; CS-0088118; FT-0775271; 1,3,6-Naphthalenetrisulfonicacid, 8-hydroxy-
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Phthalylsulfapyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[[4-[(6-methoxypyridazin-3-yl)sulfamoyl]phenyl]carbamoyl]benzoic acid; Phthazin; phthazine; 2-({4-[(6-methoxypyridazin-3-yl)sulfamoyl]phenyl}carbamoyl)benzoic acid; Oprea1_410528; Oprea1_500919; CBDivE_002694; CBDivE_003182; ARONIS24452; 3-Methoxy-6-(N(4)-phthaloylsulfanilamido)pyridazine; CHEMBL462051; CTK4B6524; DTXSID40156338; ZINC2343837; STK386836; AKOS000623327; MCULE-1206427347; ST011908; EU-0011846; N-(4-(6-METHOXY-PYRIDAZIN-3-YLSULFAMOYL)-PHENYL)-PHTHALAMIC ACID
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[3-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-ylamino)-2,2-dimethyl-propyl]-2-methoxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001223483; CHEMBL518634; HMS1673F12; HMS2898E08; ZINC850015; STL290971; AKOS000466702; MCULE-9801530407; SMR000611942; ST50275793; SR-01000527326; SR-01000527326-1
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-({3-Methyl-4-[(thiophen-2-ylcarbonyl)amino]phenyl}amino)-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_554430; Oprea1_586024; CHEMBL468891; ZINC319695; STK053488; AKOS000644725; MCULE-1404463779; SR-01000356905; SR-01000356905-1
Click to Show/Hide
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||||
| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-({2-[(2-Sulfophenyl)amino]pyrimidin-4-yl}amino)benzene-1-sulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466002; ZINC2314774; STL314696; AKOS001018626; AKOS022141455; MCULE-4406882568; SR-01000026911; SR-01000026911-1; Z56772842; 2,2'-(pyrimidine-2,4-diylbis(azanediyl))dibenzenesulfonic acid
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5-(Azepan-1-ylsulfonyl)-2-chloro-N-(2-hydroxyphenyl)benzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
ZINC01061757; Oprea1_503005; Oprea1_537972; CHEMBL518188; ZINC1061757; STK759157; AKOS000728984; MCULE-7916655557; AB00115502-01; SR-01000432477; SR-01000432477-1; 5-(1-azepanylsulfonyl)-2-chloro-N-(2-hydroxyphenyl)benzamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-O-Cyclohexyl 5-O-methyl 3,6-dimethyl-4-oxo-1,5,6,7-tetrahydroindole-2,5-dicarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000116516; SMR000093486; CHEMBL467423; BDBM44702; cid_2997361; HMS2265K07; STK405796; AKOS000662669; CCG-128409; MCULE-3548471300; ST50293241; SR-01000123804; SR-01000123804-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-Chloro-5-(diethylsulfamoyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMR000123625; Oprea1_080752; Oprea1_480629; MLS000123061; CHEMBL468471; REGID_for_CID_1117935; HMS2449D03; ZINC854134; STK756366; 2-Chloro-5-diethylsulfamoyl-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzamide; AKOS000729295; MCULE-4634818663; EU-0051560; SR-01000517070; SR-01000517070-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-[[[5-(Ethylcarbamoyl)-2-methylthiophen-3-yl]sulfonylamino]methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL448408; ZINC6680118; AKOS000762997
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-(4-Amino-5-ethoxycarbonylpyrimidin-2-yl)sulfanylpropanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL461635; AKOS017270215
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[4-[4-Ethyl-5-(2-oxo-2-thiophen-2-ylethyl)sulfanyl-1,2,4-triazol-3-yl]phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL506724
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-(2-Bicyclo[2.2.1]heptanyl)-N-[5-[2-(4-methylphenyl)sulfonylethyl]-1,3,4-thiadiazol-2-yl]acetamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BAS 06264743; CHEMBL459744; AKOS000672137; AKOS030485511
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-{4-Methoxy-3-[(pyridin-3-ylmethyl)-sulfamoyl]-phenyl}-acrylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001207409; CHEMBL466004; HMS2841K12; ZINC103105; STK806613; AKOS000531360; SMR000516545; ST50507441; (2E)-3-(4-methoxy-3-{[(3-pyridylmethyl)amino]sulfonyl}phenyl)prop-2-enoic acid; (2E)-3-{4-methoxy-3-[(pyridin-3-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Dibenzofuran-2,8-disulfonic acid bis-tert-butylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459743; HMS1690F12; ZINC4171975; AKOS000605254; MCULE-8110017782; EU-0014254; SR-01000322644; SR-01000322644-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(1,1-Dioxobenzo[d]1,2-thiazolin-3-yl)methylamino]-2-phenoxyacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000856512; CHEMBL513348; ZINC33991; HMS2678G05; STK723876; AKOS000640981; MCULE-7577677990; SMR000274869; ST048922; SR-01000518866; SR-01000518866-1; N'-(1,1-dioxido-1,2-benzothiazol-3-yl)-N'-methyl-2-phenoxyacetohydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-[Methyl(thiophen-2-ylsulfonyl)amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL511180; ZINC5016401; STK743917; AKOS000744721; MCULE-6538960707
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 76 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
GNF-PF-2272
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Methyltoxoflavin; GNF-Pf-2272; MLS000528498; SMR000121073; 1,3,6-Trimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione; BAS 00444306; 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione; 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; SR-01000322764; methyltoxoflavin; CPXHNWKHOFNPDO-UHFFFAOYSA-N; 3-methyl toxoflavin; AC1LA2XZ; 32502-62-8; cid_460747; SCHEMBL2180986; CHEMBL601757; BDBM34671; CHEBI:95315; KUC104460N; HMS2304H14; STK397047; KSC-1-228; MCULE-2510138695; NCGC00093522-02; NCGC00093522-01; HY-111117
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Bromothiophen-2-yl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420613; BDBM50438915; STK256715
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1-Ethyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1569025; SCHEMBL14019967; TF-88; ZINC4512036; BDBM50438907; STL560610; AKOS000714964; CCG-144073; MCULE-5059949824; NCGC00168410-01; D052-0144; 1-ethyl-3-(4-ethylphenyl)-6-methyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-N-methylsulfonylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420490; BDBM50438885
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
N-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-1-methyl-6-oxo-5-phenylmethoxypyrimidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420488; BDBM50438887
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
N-[3-(2,4-Dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420475; BDBM50438853
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420481; BDBM50438894
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1-(Cyclopropylmethyl)-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420509; BDBM50438904
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
Schembl21221794
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420507; BDBM50438864; 10-(3-hydroxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(3-Hydroxy-4-methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420469; BDBM50438859
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
6-Chloro-4-hydroxy-10-phenylpyrimido[4,5-b]quinolin-2(10H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL224548; 6-chloro-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione; Oprea1_805552; ZINC9334535; BDBM50438875; STL047822; STL570613; AKOS005701409; AKOS030521783; MCULE-8813457365
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(m-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420617; BDBM50438909
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
6-(4-Ethylphenyl)-1,3-dimethylpteridine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420484; BDBM50438891
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Ethylphenyl)-1-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420512; BDBM50438901
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
N-[3-(7-Chloro-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420476; BDBM50438852
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(4-methylphenyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1450796; SCHEMBL2181779; BDBM50438910; STK256714; CCG-144088; MCULE-2626397605; NCGC00168404-01; 1,6-dimethyl-3-(4-methylphenyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; 1,6-Dimethyl-3-(p-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(4-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420612; BDBM50438916
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(1,3-thiazol-4-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420611; BDBM50438917
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-Phenyl-8-(trifluoromethyl)pyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420505; BDBM50438866
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-3-methyl-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420494; ZINC428961; BDBM50438878; STK828427; AKOS001806107; MCULE-2375756247; EU-0059319; SR-01000095891; SR-01000095891-1
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-Benzyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1394266; SCHEMBL13272610; BDBM50438921; AKOS000714902; NCGC00093527-01
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-piperidin-4-ylpyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420500; BDBM50438871
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
[1-[4-(3,4-Dimethoxyphenyl)thiophene-2-carbonyl]piperidin-3-yl]-dimethoxyphosphorylmethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420489; BDBM50438886
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(3-Methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420467; BDBM50438861
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-Cyclohexyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420517; SCHEMBL3473714; BDBM50438896
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(8-Cyano-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420477; BDBM50438851
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-Benzyl-8-chloro-2-hydroxypyrimido[4,5-b]quinolin-4(10H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420492; ZINC538815; BDBM50438880; STK649138; AKOS005579969; AKOS032388078; MCULE-7996076617; 10-benzyl-8-chloropyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
Pyrimido(5,4-e)-1,2,4-triazine-5,7(1H,6H)-dione, 3-(3,4-dimethoxyphenyl)-1,6-dimethyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC280174; UNII-5PZ2F5VUW0; 5PZ2F5VUW0; CHEMBL2094689; DNDI1417416; NSC 280174; ChemDiv2_000538; Oprea1_032004; SCHEMBL15032575; CTK4G8800; DTXSID70186229; HMS1370I10; ZINC378638; 3-(3,4-Dimethoxyphenyl)toxoflavine; BDBM50438918; STK397049; AKOS001632580; MCULE-3631924503; NSC-280174; EU-0038106; ST50904462; SR-01000432319; SR-01000432319-1; 3-(3,4-dimethoxyphenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-Cyclopropyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420515; SCHEMBL3472625; BDBM50438898
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
7-Amino-1-methyl-3-(4-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420485; BDBM50438890
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(2-phenylethyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420609; SCHEMBL3474479; BDBM50438920
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
4-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-N-methylsulfonylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420491; BDBM50438884
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1-Cyclopropyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420508; BDBM50438906
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(oxan-4-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420518; BDBM50438895
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione,9-chloro-10-phenyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420495; BDBM50438877
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-cyclohexylpyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420499; BDBM50438872
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
Schembl21234361
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420506; BDBM50438865
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
Walrycin B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Walrycin-B; CHEMBL1096283; WalrycinB; 4-tert.Butylcalix[6]arene; SCHEMBL3472472; GTPL11256; KS-00001DAS; AOB6616; EX-A363; BCP09097; ZINC4512033; BDBM50438912; MFCD07188899; STL560612; AKOS001872828; NCGC00371145-02; BS-17871; DA-40918; HY-18219; QC-11394; AB0098419; FT-0700392; S0195; A11819; SR-01000100642; J-690379; SR-01000100642-1; D052-0142
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-[3-(Hydroxymethyl)phenyl]-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420466; BDBM50438862
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
6-Benzyl-3-(4-ethylphenyl)-1-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420514; BDBM50438899
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Ethylphenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420615; BDBM50438913; 3-(4-Ethylphenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-(4-methoxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420502; BDBM50438869
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-[4-(trifluoromethoxy)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420616; BDBM50438911; 1,6-Dimethyl-3-(4-(trifluoromethoxy)phenyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-(4-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420501; BDBM50438870
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(1H-Indazol-6-yl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420478; BDBM50438850
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Ethylphenyl)-6-methyl-1-propylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2417582; BDBM50438905
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
2,4-Dioxo-10-[3-(1h-Tetrazol-5-Yl)phenyl]-2,3,4,10-Tetrahydropyrimido[4,5-B]quinoline-8-Carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420480; SCHEMBL19372794; BDBM50438848; Q27456379
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(1H-Indazol-4-yl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420479; BDBM50438849
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione, 8-chloro-10-phenyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL223823; CTK3D0394; DTXSID70359198; ZINC554418; BDBM50438883; STK654457; AKOS005585563; AKOS028111620; MCULE-3978413344; 8-chloro-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione; 8-chloro-2-hydroxy-10-phenylpyrimido[4,5-b]quinolin-4(10H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-methylpyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420497; BDBM50438874
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| Activity |
IC50 > 200000 nM
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[3] | |||
| Compound Name |
N-[3-(8-Cyano-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420474; BDBM50438854
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| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(4-Bromophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420471; BDBM50438857
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| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-Phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL471342; Oprea1_827515; ZINC554718; BDBM50438882; STK377163; STK657568; AKOS005448130; AKOS005587626; MCULE-8920259626; ST50858289; 2-hydroxy-10-phenylpyrimido[4,5-b]quinolin-4(10H)-one; 10-phenyl-3,10-dihydropyrimidino[4,5-b]quinoline-2,4-dione
Click to Show/Hide
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| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-naphthalen-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420610; BDBM50438919; 1,6-Dimethyl-3-(naphthalen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
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| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
2-[3-(8-Cyano-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420473; BDBM50438855
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| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(3-Fluorophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420470; BDBM50438858
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
7-Chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420496; BDBM50438876
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(3-Aminophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420472; BDBM50438856
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-(3-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420503; BDBM50438868
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Ethylphenyl)-6-methyl-1-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420510; BDBM50438903
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-cyclopropylpyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420498; BDBM50438873
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-propylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000718932; SMR000291200; CHEMBL1325945; SCHEMBL15032586; BDBM34905; cid_3164059; HMS2710G14; CCG-144064; NCGC00093523-01; SR-01000100610; US9073941, 617; SR-01000100610-1; Q27164241; 1,6-dimethyl-3-propyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione; 1,6-dimethyl-3-propyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone; 1,6-Dimethyl-3-propylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1-Benzyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420511; BDBM50438902
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(4-Methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420468; BDBM50438860
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1-Ethyl-3-(4-ethylphenyl)-6-methylpyrimido[4,5-c]pyridazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420483; BDBM50438892
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-(2-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420504; BDBM50438867
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(o-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1449180; BDBM50438908; AKOS000714933; NCGC00168409-01; SR-01000100636; SR-01000100636-1; D052-0132
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-(4-Hydroxyphenyl)-2,4-Dioxo-2,3,4,10-Tetrahydropyrimido[4,5-B]quinoline-8-Carbonitrile
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420465; SCHEMBL21221783; BDBM50438863; Q27456381; 10-(4-hydroxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Ethylphenyl)-1-methyl-6-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420513; BDBM50438900
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
10-Methylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS002703948; CHEMBL228772; NSC106927; pyrimido[4,5-b]quinoline-2,4(3h,10h)-dione, 10-methyl-; 10-methylpyrimido[4,5-b]quinoline-2,4-dione; Oprea1_590946; 10-Methy-5-deazaisoalloxazine; SCHEMBL3834002; CTK4F9132; DTXSID90296016; ZINC1698103; ANW-52680; BDBM50438881; AKOS015850927; NSC-106927; SMR001570660; DB-000785; AM20051024; FT-0734845; W-2534; 10-Methyl-pyrimido[4,5-b]1,2-dihydroquinolin-2,4-dione; 10-methyl-2H,3H,4H,10H-pyrimido[4,5-b]quinoline-2,4-di-one
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420482; BDBM50438893; STK215565; ZINC18219263; AKOS005418784; MCULE-6255382282
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-phenylpyrimido[5,4-E][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione, 1,6-dimethyl-3-phenyl-; P00002; Oprea1_364785; Oprea1_823603; SCHEMBL2183740; CHEMBL1527391; BDBM36527; CTK1B9176; DTXSID50332727; ZINC267655; 1,6-dimethyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione; STK249719; AKOS000714986; CCG-144081; MCULE-5113091276; NCGC00093524-01; NCGC00093524-02; NCGC00093524-03; EU-0004879; ST50860613; MLS-0066984.0001; MLS-0066984.0002; D052-0163; 1,6-dimethyl-3-phenyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione; 1,6-dimethyl-3-phenyl-6-hydropyrimidino[5,4-e]1,2,4-triazine-5,7-dione; 1,6-dimethyl-3-phenyl-1H,5H,6H,7H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione, 10; 1,6-Dimethyl-3-phenylpyrimido[5,4-E][1,2,4]triazine-5,7(1H,6H)-dione #; Pyrimido(5,4-e)-1,2,4-triazine-5,7-(1H,6H)-dione, 3-phenyl-1,6-dimethyl-
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
1,6-Dimethyl-3-(4-phenylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420614; BDBM50438914
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-Cyclopentyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420516; BDBM50438897
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
3-(4-Chlorophenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000523518; SMR000122591; 3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione; 3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione; 3-(4-chlorophenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; Opera_ID_1301; Oprea1_202505; Oprea1_319826; cid_460749; SCHEMBL2180580; CHEMBL1334062; BDBM40314; HMS2389E18; NSC749675; STK397048; AKOS024302524; MCULE-8325440563; NSC-749675; NCGC00168386-01; ST50002652; SR-01000432316; US9073941, 603; SR-01000432316-1; 3-(4-chlorophenyl)-1,6-e][1,2,4]triazine-5,7-dione; 1,6-Dimethyl-3-(4-chlorophenyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; 1H-Pyrimido[5,4-E][1,2,4]triazine-5,7-dione, 3-(4-chlorophenyl)-1,6-dimethyl-; 3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
8-Chloro-10-(4-methylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420493; ZINC521146; BDBM50438879; STK549537; AKOS005477319; MCULE-8139200936; 8-chloro-10-(p-tolyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors. J Med Chem. 2009 Jan 8;52(1):20-32. | ||||
| REF 2 | Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors. J Med Chem. 2012 Apr 12;55(7):3101-12. | ||||
| REF 3 | Toxoflavins and deazaflavins as the first reported selective small molecule inhibitors of tyrosyl-DNA phosphodiesterase II. J Med Chem. 2013 Aug 22;56(16):6352-70. | ||||
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