Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
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| Target ID | T11764 | Target Info | |||
| Target Name | Discoidin domain-containing receptor 2 (DDR2) | ||||
| Synonyms |
Tyrosine-protein kinase TYRO10; Receptor protein-tyrosine kinase TKT; Neurotrophic tyrosine kinase, receptor-related 3; Discoidin domain-containing receptor tyrosine kinase 2; Discoidin domain receptor 2; DDR2; CD167 antigen-like family member B
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| Target Type | Patented-recorded Target | ||||
| Gene Name | DDR2 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-Amino-2-phenyl-4H-chromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
3-aminoflavone; 3-amino-2-phenylchromen-4-one; NSC65031; NSC-65031; CHEMBL476011; NSC 65031; Oprea1_677314; SCHEMBL622846; CTK5C9376; 3-amino-2-phenyl-chromen-4-one; DTXSID50219342; ZINC518347; BDBM50014359; AKOS030489272; MCULE-9463389670
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| Activity |
IC50 = 80800 nM
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[1] | |||
| Compound Name |
1-(3-Tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)-3-(naphthalen-1-yl)urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL578172; SCHEMBL12245428; BDBM50303586; 1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)-3-(naphthalen-1-yl)urea, 1d
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
1-[1-(4-Methylphenyl)-3-tert-butyl-1H-pyrazole-5-yl]-3-(1-naphthyl)urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL420047; diaryl urea compound 6; BIRB-796 Analog 4; SCHEMBL12245431; BDBM14837; 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-naphthalen-1-ylurea; 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-naphthalen-1-ylurea
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | Identification of type II and III DDR2 inhibitors. J Med Chem. 2014 May 22;57(10):4252-62. | ||||
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