Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T11451 | Target Info | |||
| Target Name | Toll-like receptor 9 (TLR9) | ||||
| Synonyms |
UNQ5798/PRO19605; TLR-9; CD289
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| Target Type | Clinical trial Target | ||||
| Gene Name | TLR9 | ||||
| Biochemical Class | Toll-like receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Chembl4280799
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL906154; BDBM50467793; Tert-butyl 4-(6-methoxy-7-oxo-1H-quinazolin-4-yl)piperazine-1-carboxylate; tert-butyl 4-(7-hydroxy-6-methoxyquinazolin-4-yl)piperazinecarboxylate
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Chembl4279904
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL19385121; BDBM50467790
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| Activity |
IC50 = 51000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Activity-guided development of potent and selective toll-like receptor 9 antagonists. Eur J Med Chem. 2018 Nov 5;159:187-205. | ||||
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