Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T11283 | Target Info | |||
| Target Name | Mitochondrial matrix protein P1 (HSPD1) | ||||
| Synonyms |
P60 lymphocyte protein; HuCHA60; Hsp60; Heat shock protein 60; HSP-60; Chaperonin 60; CPN60; 60 kDa heat shock protein, mitochondrial; 60 kDa chaperonin
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| Target Type | Clinical trial Target | ||||
| Gene Name | HSPD1 | ||||
| Biochemical Class | Chaperonin ATPase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-Bromo-2-[(1R,2S)-1,2-dimethyl-3-methylidenecyclopentyl]-5-methylphenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4099907; Allolaurinterol; CTK5J1595; BDBM50260459; 4-bromo-2-[(1R,2S)-1,2-dimethyl-3-methylene-cyclopentyl]-5-methyl-phenol; 4-Bromo-2-[(1R,2S)-1,2-dimethyl-3-methylenecyclopentyl]-5-methylphenol; Phenol, 4-bromo-2-[(1R,2S)-1,2-dimethyl-3-methylenecyclopentyl]-5-methyl-
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| Compound Name |
(4S,6S)-7-Hydroxy-3,6,9-trimethyl-4-(2-methylprop-1-enyl)-5,6-dihydro-4H-phenalene-1,2-dione
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Investigative | Compound Info | ||
| Synonyms |
elisabatin A; NSC704379; PEH-II; CHEMBL494655; CTK5J8515; BDBM50260460; NSC-704379; NCI60_037264
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| Activity |
IC50 ~ 100000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A. Bioorg Med Chem Lett. 2017 Sep 1;27(17):4082-4085. | ||||
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