Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T09909 | Target Info | |||
| Target Name | Angiotensin II receptor type-2 (AGTR2) | ||||
| Synonyms |
Type-2 angiotensin II receptor; Angiotensin II type-2 receptor; Angiotensin II receptor 2; AT2
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| Target Type | Successful Target | ||||
| Gene Name | AGTR2 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 5 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Tert-butyl N-[[(2S,3S)-2-[[3-(imidazol-1-ylmethyl)benzoyl]amino]-3-methylpentanoyl]amino]carbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105382
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| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(2S,3S)-1-[2-(Benzenesulfonyl)hydrazinyl]-3-methyl-1-oxopentan-2-yl]-3-(imidazol-1-ylmethyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105393
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| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(2S,3S)-1-(2-Butylsulfonylhydrazinyl)-3-methyl-1-oxopentan-2-yl]-3-(imidazol-1-ylmethyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105384
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| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
3-(Imidazol-1-ylmethyl)-N-[(2S,3S)-3-methyl-1-oxo-1-(2-pentylsulfonylhydrazinyl)pentan-2-yl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105385
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| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
(2S,3S)-2-[[3-(Imidazol-1-ylmethyl)benzoyl]amino]-3-methylpentanoic acid;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105395
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| Activity |
Ki = 110000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of isoleucine derived angiotensin II AT(2) receptor ligands. Bioorg Med Chem Lett. 2014 Jan 15;24(2):476-9. | ||||
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