Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T09395 | Target Info | |||
| Target Name | Chitinase (CHIT1) | ||||
| Synonyms |
Chitotriosidase1; Chitinase1; CHIT1
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|
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| Target Type | Literature-reported Target | ||||
| Gene Name | CHIT1 | ||||
| Biochemical Class | Glycosylase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 8 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
NC1=NNC(=N1)N1CCC(CC1)NC(=O)NC1=CC=C(Br)C=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4059615; SCHEMBL16825693; BDBM50243702
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
NC1=NNC(=N1)N1CCC(CC1)C(=O)NCC1=CC=C(Br)C=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4071558; SCHEMBL16825712; BDBM50243809
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
CN(CC1CCN(CC1)C1=NC(N)=NN1)CC1=CC=C(Br)C=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079129; SCHEMBL16826174; BDBM50243716
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
NC1=NNC(=N1)N1CCC(CC1)NC(=O)CC1=CC=C(Br)C=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4087924; SCHEMBL16825818; BDBM50243703
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
NC1=NNC(=N1)N1CCN(CC1)C(=O)COC1=CC=C(Br)C=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098590; SCHEMBL16826413; BDBM50243701
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
NC1=NNC(=N1)N1CCC(CC1)N(S(=O)(=O)CC1=CC=C(C=C1)Br)C
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4095625; SCHEMBL16826403; BDBM50243808
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
CN(Ccc1=CC=CC=C1)C1ccn(CC1)C1=NC(N)=NN1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4062909; SCHEMBL16825846; BDBM50243686
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
NC1=NNC(=N1)N1CCC(CC1)NS(=O)(=O)CC1=CC=C(Br)C=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4068260; SCHEMBL16825761; BDBM50243704
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma. J Med Chem. 2018 Feb 8;61(3):695-710. | ||||
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